[1]洪毅.输血不良反应发生与疾病类型及血液输入成分的相关性研究[J].现代检验医学杂志,2020,35(05):87-89,141.[doi:10.3969/j.issn.1671-7414.2020.05.022]
　HONG Yi.Correlation between Adverse Reactions to Blood Transfusion and Disease Type and Blood Input Components[J].Journal of Modern Laboratory Medicine,2020,35(05):87-89,141.[doi:10.3969/j.issn.1671-7414.2020.05.022]
点击复制

输血不良反应发生与疾病类型及血液输入成分的相关性研究()
分享到：

《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年05期
页码:
87-89,141
栏目:
论著
出版日期:
2020-11-01

文章信息/Info

Title:
Correlation between Adverse Reactions to Blood Transfusion and Disease Type and Blood Input Components
文章编号:
1671-7414（2020）05-087-04
作者:
洪毅
西安高新医院输血科, 西安 710075
Author(s):
HONG Yi
Department of Blood Transfusion，Xi’an Gaoxin Hospital, Xi’an 710075,China
关键词:
输血不良反应; 血液成分; 发热反应; 过敏反应
分类号:
R457.13
DOI:
10.3969/j.issn.1671-7414.2020.05.022
文献标志码:
A
摘要:
目的　通过对输血不良反应发生与疾病类型及血液输入成分的相关性研究，为临床安全输血提供依据支持。方 法　根据医院信息管理系统提供的数据，2008 年1 月~2019 年12 月输血总人次为14 958 例，其中发生输血不良反应 病例125 例。分析其发生类型、输入血液成分、病种之间的关系。结果　2008 到2019 年共发生输血不良反应125 例， 输血不良反应率为0.83%（125/14 958），发热反应率最高，共62 例（0.41%），其次为过敏反应51 例（0.34%）。在 输注成分中以单采血小板引起的输血不良反应发生率最高（1.47%，25/1 696），其次为红细胞（0.96%，75/7 538）、 血浆（0.49%，25/5 012），其它血液成分未见发生，差异均有统计学意义（χ2=8.0，52.16，13.52，均P<0.05）；临床 科室之间、病种之间、单次输血者和反复输血者之间输血不良反应发生率差异具有统计学意义（χ2=39.252，P<0.05）。 结论　输血科应加强临床科室的培训，提高医生对输血不良反应的认识判别能力，确保临床输血安全。
Abstract:
Objective　To study the correlation between adverse reactions of blood transfusion and disease types and blood transfusion components, so as to provide basis and support for clinical safe blood transfusion. Methods　According to the data provided by the hospital information management system, the total number of blood transfusion cases from January 2008 to December 2019 was 14 958, including 125 cases of adverse reactions. The relationship among the occurrence type, blood components and disease types was analyzed. Results　From 2008 to 2019, there were 125 cases of adverse reactions of blood transfusion, the adverse reaction rate of blood transfusion was 0.83% (125 / 14 958), the fever reaction rate was the highest, 62 cases (0.41%), followed by 51 cases of allergic reaction (0.34%). The incidence of adverse reactions to blood transfusion caused by single platelet in infusion components was highest (1.47%，25/1 696), followed by red blood cells (0.96%，75/7 538), plasma (0.49%，25/5 012), and no other blood components were observed, with statistically significant differences (χ2=8.0， 52.16，13.52，all P<0.05). Conclusion　The department of blood transfusion should strengthen the training of the clinical department, improve the doctor’s ability to recognize and identify the adverse reactions of blood transfusion, and ensure the safety of clinical blood transfusion.

参考文献/References:

[1] MONCHARMONT P, QUITTANCON E, BARDAY G, et al. Adverse transfusionreactions in patients with aplastic anemia or myelodysplastic syndromes[J]. Vox Sanguinis, 2019, 114(4): 349-354.
[2] 刘忠．全血和成分血使用标准释义[M]. 北京: 人民 卫生出版社, 2019:83-91． LIU Zhong. Standard interpretation of whole blood and blood components[M]. Beijing:People’s Medical Publishing House, 2019:83-91.
[3] 临床输血规范流程协作组．溶血性输血反应与细菌 性输血反应处置流程[J]. 中国输血杂志, 2012, 25 （9）: 824-825． Clinical Blood Transfusion Process Collaboration Group. Treatment process of hemolytic transfusion reaction and bacterial transfusionreaction[J].Chinese Journal of Blood Transfusion.2012,25(9): 824-825.
[4] 苏莉, 王红波, 杨家焕, 等.477 例临床输血不良反 应调查及分析[J]．中国输血杂志，2019，32（10）： 1027-1031． SU Li, WANG Hongbo, YANG Jiahuan, et al. Investigation and analysis of 477 cases of adverse reactions in clinical blood transfusion[J]. Chinese Journal of Blood Transfusion，2019,32(10): 1027- 1031.
[5] 孙鸿，吴宁伟，孙艳．南京地区某三级医院输血 不良反应情况[J]. 中国临床研究, 2017, 30（12）: 1667-1669． SUN Hong, WU Ningwei, SUN Yan. Adverse blood transfusion reactions in a tertiary hospital in Nanjing[ J]. Chinese Journal of Clinical Research.2017, 30(12):1667-1669.
[6] 胡佳林，周浩锋．214 例患者输血不良反应临床分 析[J]. 重庆医学, 2018, 47（8）: 1068-1069． HU Jialin, ZHOU Haofeng. Clinical analysis of 214 cases of blood transfusion adverse reactions[J]. Chongqing Medicine, 2018, 47(8):1068-1069.
[7] 褚晓凌，郭永建．国际输血协会《非感染性输血不 良反应监测标准》之解读[J]. 中国输血杂志, 2012, 25（8）: 812-814． CHU Xiaoling, GUO Yongjian. Interpretation of the international blood transfusion association of noninfectious blood transfusion adverse reaction monitoring standard [J]. Chinese Journal of Blood Transfusion. 2012, 25(8):812-814.
[8] 中华人民共和国卫生健康委员会. 国卫医函〔2019〕 98 号：血站技术操作规程[R]. 北京: 人民卫生出版 社,2019:18. National Health Commission of the People’s Republic of China .Medical Letter of the State Health Office
[2019] No. 98:Blood Station Technical Operation Rules [R]. Beijing:People’s Medical Publishing House, 2019:18.

备注/Memo

备注/Memo:
作者简介：洪毅（1975-）男，本科，副主任技师，主要从事输血管理及输血检验等相关研究，E-mail:1967113703@qq.com。
更新日期/Last Update: 2020-10-30