[1]张书婉,黄君华,吴文婧,等.外周血 NLR 与 PLR 对儿童完全型川崎病冠状动脉损伤的预测分析[J].现代检验医学杂志,2020,35(06):38-41.[doi:doi:10.3969/j.issn.1671-7414.2020.06.010]
　ZHANG Shu-wan,HUANG Jun-hua,WU Wen-jing,et al.Prediction Analysis of NLR and PLR for the Development of Coronary ArteryLesions in Patients with Complete Kawasaki Disease[J].Journal of Modern Laboratory Medicine,2020,35(06):38-41.[doi:doi:10.3969/j.issn.1671-7414.2020.06.010]
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外周血 NLR 与 PLR 对儿童完全型川崎病冠状动脉损伤的预测分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年06期
页码:
38-41
栏目:
论著
出版日期:
2020-12-30

文章信息/Info

Title:
Prediction Analysis of NLR and PLR for the Development of Coronary ArteryLesions in Patients with Complete Kawasaki Disease
文章编号:
1671-7414（2020）06-038-05
作者:
张书婉1 ; 黄君华2 ; 吴文婧3 ; 祝撷英1 ; 杨　立3 ; 曹三成1
（1. 西安市儿童医院检验科，西安 710003；2. 西安医学院医学技术学院，西安 710021；3. 西安交通大学第一附属医院检验科，西安 710061）
Author(s):
ZHANG Shu-wan 1 ;  HUANG Jun-hua 2 ;  WU Wen-jing 3 ;  ZHU Xie-ying 1 ;  YANG Li 3 ;  CAO San-cheng 1 .
(1.Department of Clinical Laboratory, Xi’an Children’s Hospital，Xi’an 710003, China; 2.Department of MedicalTechnology, Xi’an Medical University,Xi’an 710021, China; 3.Department of Clinical Laboratory, the First AffiliatedHospital of Xi’an Jiaotong Uni
关键词:
川崎病; 冠状动脉损伤; 中性粒细胞与淋巴细胞比值; 血小板与淋巴细胞比值
分类号:
R725.5；R446.11
DOI:
doi:10.3969/j.issn.1671-7414.2020.06.010
文献标志码:
A
摘要:
目的　探讨中性粒细胞与淋巴细胞比值（NLR）和血小板与淋巴细胞比值（PLR）预测完全型川崎病（CKD）患儿冠状动脉损伤（CAL）的价值。方法　回顾性分析 2018 年 1 月 1 日 ~12 月 31 日在西安市儿童医院和西安交通大学第一附属医院确诊为 CKD 的 185 例患儿的临床资料，其中发生 CAL 者 37 例，未发生 CAL 者 148 例；选取同时期93 例上呼吸道病毒感染儿童为发热对照组，60 例健康体检儿童为健康对照组。收集所有纳入对象的血细胞检测结果并进行统计学分析。结果　CKD 患儿中发生 CAL 者 NLR 和 PLR 均高于未发生 CAL 者，差异有统计学意义（χ 2 =3.69, 4.13,均P<0.01） ；NLR和PLR预测川崎病CAL的cut-off 值分别为4.13和126.82，敏感度和特异度分别为83.8%和76.1%（NLR）及81.1%和67.0%（PLR）；NLR与PLR联合预测CAL的敏感度和特异度分别为86.5%和80.7%，ROC曲线下面积0.874。结论　CKD 急性期 NLR 与 PLR 对预测患儿是否发生 CAL 具有一定的价值。

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更新日期/Last Update: 2020-12-20