[1]洪生静,谢小娟,周伶俐,等.血浆纤维蛋白原不同检测系统间检测结果的一致性分析及质控品的互通性探讨[J].现代检验医学杂志,2021,36(02):105-110.[doi:doi:10.3969/j.issn.1671-7414.2021.02.025]
 HONG Sheng-jing,XIE Xiao-juan,ZHOU Ling-li,et al.Analysis of Fib Consistency among Different Detection Systems and Discussion on Commutability of Quality Control Materials[J].Journal of Modern Laboratory Medicine,2021,36(02):105-110.[doi:doi:10.3969/j.issn.1671-7414.2021.02.025]
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血浆纤维蛋白原不同检测系统间检测结果的一致性分析及质控品的互通性探讨()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年02期
页码:
105-110
栏目:
论 著
出版日期:
2021-04-30

文章信息/Info

Title:
Analysis of Fib Consistency among Different Detection Systems and Discussion on Commutability of Quality Control Materials
文章编号:
1671-7414(2021)02-105-06
作者:
洪生静谢小娟周伶俐
(1. 西安医学院,西安 710021;2. 陕西省人民医院,西安 710068)
Author(s):
HONG Sheng-jing1 XIE Xiao-juan2 ZHOU Ling-li1 et al
(1.Xi’an Medical College, Xi’an 710021,China;2.Shaanxi Provincial People’s Hospital, Xi’an 710021,China)
关键词:
纤维蛋白原 凝血分析仪 质控品
分类号:
R446.112
DOI:
doi:10.3969/j.issn.1671-7414.2021.02.025
文献标志码:
A
摘要:
目的 比较7种不同检测系统测定血浆纤维蛋白原 (Fib)结果的一致性,并观察不同厂家质控品的基质效应,评价互通性。方法 在Sysmex CS 5100, IL ACL TOP 700, STA-Compact,雷杜Rayto RAC 1830,众驰Zonci XL 1000i,赛科希德Succeeder SF 8100配套检测系统及Sysmex CS 5100仪器(太阳试剂)非配套检测系统上检测Fib不同水平患者血浆样本40份。参考美国临床实验室标准化协会(CLSI)的EP9-A2文件,对结果进行统计学分析,评价不同检测系统间Fib检测结果是否具有一致性。同时选取8个厂家凝血质控品在7种检测系统上检测Fib ,参考EP14-A3文件和《基质效应与互通性评估指南》(WS/T 356-2011)的要求,评价质控品一致程度及互通性。结果 不同系统检测患者样本Fib结果相关系数(r2)为0.674~0.944 ,以Sysmex CS 5100及STA-Compact作为比对系统,检测系统间结果具有临床可接受性(除赛科希德Succeeder SF 8100配套检测系统部分结果存在差异)。8个厂家凝血质控品,Fib检测结果CV值在5.49%~14.51%之间,不同厂家凝血质控品在7种检测系统间无法评估互通性。结论 7种检测系统间Fib检测结果相关性不佳,Fib检测结果在不同检测系统间是否具有一致性需进一步研究,无法评估各厂家凝血质控品互通性。

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备注/Memo

备注/Memo:
作者简介:洪生静(1995-),女,在读硕士,初级检验医师,主要研究方向:临床检验诊断,E-mail:1135340488@qq.com。
通讯作者:魏力强(1962-),男,主任检验师,E-mail:wlq8399@126.com。
更新日期/Last Update: 2021-04-10