[1]秦智谦,常 毅,郝万鹏.乌鲁木齐地区鲍曼不动杆菌感染的临床分布及耐药性分析[J].现代检验医学杂志,2015,30(04):77-79.[doi:10.3969/j.issn.1671-7414.2015.04.021]
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乌鲁木齐地区鲍曼不动杆菌感染的临床分布及耐药性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年04期
页码:
77-79
栏目:
论著
出版日期:
2015-08-10

文章信息/Info

文章编号:
1671-7414(2015)04-077-03
作者:
秦智谦1常 毅1郝万鹏2
1.乌鲁木齐市头屯河区中心医院,乌鲁木齐 830023;
2.乌鲁木齐市温泉康复医院,乌鲁木齐 830017
关键词:
鲍曼不动杆菌 感染 耐药性
分类号:
R378.2; R446.5
DOI:
10.3969/j.issn.1671-7414.2015.04.021
文献标志码:
A
摘要:
目的 了解乌鲁木齐地区鲍曼不动杆菌(acinetobacter baumannii,Ab)感染的临床分布特征及耐药性,为临床合理用药、有效控制医院感染提供依据。方法 对2012~2014年临床各类标本中分离的Ab分布特征及耐药性进行回顾性分析,细菌分离培养依据《全国临床检验操作规程》进行,使用合肥恒星科技有限公司HX-21细菌鉴定分析仪进行菌种鉴定及药敏测定,药敏检测为最低抑菌浓度(MIC)法,采用合肥恒星科技公司细菌鉴定分析系统软件进行数据分析。结果2012~2014年共检出Ab 173株,三年检出率分别为1.1%,1.7%和5.2%,检出率逐年提高; 其中呼吸道标本检出率最高,共127株(73.4%),其次依次为创口分泌物(9.3%)、脓液(7.5%)及尿液标本(5.8%); 科室分布也以儿科(40.5%)和呼吸内科(36.4%)为主。耐药分析显示Ab对头孢唑林全耐药,对氨苄西林耐药率由最初的94.4%上升为100%,对其它β-内酰胺类抗生素的耐药性均呈现不同程度逐年上升的态势。共检出91株多重耐药菌株,检出率为52.6%,检出耐碳青霉烯类菌株10株,检出率为5.8%。结论乌鲁木齐地区Ab感染以呼吸道感染为主,耐药现象严重。临床科室应根据药敏结果合理使用抗菌药物,减少耐药菌株的产生。

参考文献/References:

[1] 陈佰义,何礼贤,胡必杰,等.中国鲍曼不动杆菌感染诊治与防控专家共识[J].中华医学杂志,2012,92(2):76-81.
Chen BY,He LX,Hu BJ,et al.Expert consensus of Acinetobacter baumannii infection diagnosis and prevention in China[J].National Medical Journal of China,2012,92(2):76-81.
[2] 叶应妩,王毓三,申子瑜.全国临床检验操作规程[S].3版.南京:东南大学出版社,2006:736-833.
Ye YW,Wang YS,Shen ZY.National guide to clinical laboratory procedures[S].3th Ed.Nanjing:Southeast University Press,2006:736-833.
[3] 李保强,孙跃岭,翟如波,等.308株鲍氏不动杆菌感染分布及耐药性分析[J].中国实验诊断学,2012,16(5):820-822.
Li BQ,Sun YL,Zhai RB,et al.Analysis on of infection distribution and drug resistance of 308 strains Acinetobacter baumannii[J].ChineseJournal of Laboratory Diagnosis,2012,16(5):820-822.
[4] 王成军,许 勇,王林海,等.鲍氏不动杆菌感染的临床分布特征及耐药性分析[J].中华医院感染学杂志,2014,24(17):4179-4181.
Wang CJ,Xu Y,Wang LH,et al.Clinical distribution and drug resistance of Acinetobacter baumannii causing infections[J].Chinese Journal ofNosocomiology,2014,24(17):4179-4181.
[5] 王玫红,怀丽梅,赵鑫亮.老年肺部感染患者病原菌耐药性分析及治疗策略[J].中华医院感染学杂志,2013,23(2):298-300.
Wang MH,Huai LM,Zhao XL.Drug resistance of pathogens causing pulmonary infections in the elderly and treatment strategies[J].Chinese Journal of Nosocomiology,2013,23(2):298-300.
[6] 王 军,余清源,刘 华,等.鲍氏不动杆菌临床分离株的耐药性变迁[J].中华医院感染学杂志,2014,24(18):4429-4431.
Wang J,Yu QY,Liu H,et al.Change of antimicrobial resistance of clinical isolates of Acinetobacter baumannii[J].Chinese Journal of Nosocomiology,2014,24(18):4429-4431.
[7] 张希凤,张丽霞,张 洁.泛耐药鲍氏不动杆菌的耐药性分析及控制研究[J].中华医院感染学杂志,2014,24(22):5480-5482.
Zhang XF,Zhang LX,Zhang J.Drug resistance of pandrug-resistantAcinetobacter baumannii and study on prevention and treatment[J].ChineseJournal of Nosocomiology,2014,24(22):5480-5482.
[8] 雷彦平.本院鲍曼不动杆菌近5年耐药率的变化趋势[J].中国临床药理学杂志,2012,28(5):330-332.
Lei YP.Trend of change of antimicrobial resistance against Acinetobacter baumannii in our hospital from the year 2007 or 2011[J].Chinese Journal of Clinical Pharmacology,2012,28(5):330-332.
[9] 曾 利,徐 慧,张傅山.河南省某医院鲍曼不动杆菌的临床分布及耐药性观察[J].郑州大学学报(医学版),2010,45(4):664-666.
Zeng L,Xu H,Zhang FS.Clinical distribution and antibiotic resistance observation of Acinetobacter baumannii in a hospital of Henan Province[J].Journal of Zhengzhou University(Medical Sciences),2010,45(4):664-666.

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备注/Memo

备注/Memo:
作者简介:秦智谦(1968-),女,大专,主管检验师,研究方向:微生物,Tel:13999892036,E-mail:974698394@qq.com。
更新日期/Last Update: 2015-08-10