[1]王 妍,黄钦贤,林章礼,等.汕头地区女性HPV的感染状况回顾[J].现代检验医学杂志,2015,30(04):122-124.[doi:10.3969/j.issn.1671-7414.2015.04.036]
　WANG Yan,HUANG Qin-xian,LIN Zhang-li,et al.Review of HPV Infection Status of the Women in Shantou Region[J].Journal of Modern Laboratory Medicine,2015,30(04):122-124.[doi:10.3969/j.issn.1671-7414.2015.04.036]
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汕头地区女性HPV的感染状况回顾()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年04期
页码:
122-124
栏目:
综合报道·经验交流
出版日期:
2015-08-10

文章信息/Info

Title:
Review of HPV Infection Status of the Women in Shantou Region
文章编号:
1671-7414(2015)04-122-03
作者:
王 妍; 黄钦贤; 林章礼; 郭少君
汕头市第二人民医院检验科,广东汕头 515011
Author(s):
WANG Yan; HUANG Qin-xian; LIN Zhang-li; GUO Shao-jun
Department of Clinical Laboratory, Second People's Hospital of Shantou,Guangdong Shantou 515011,China
关键词:
人乳头瘤病毒;  宫颈癌;  基因分型;  宫颈脱落细胞
分类号:
R373; R446.5
DOI:
10.3969/j.issn.1671-7414.2015.04.036
文献标志码:
A
摘要:
目的 回顾过去一年汕头地区女性人群的人乳头瘤病毒(human papillomavirus,HPV)的感染状况。方法 收集2013～2014年某院妇科门诊就诊的3 664例女性患者的宫颈脱落细胞,行HPV基因扩增及分型诊断,检测HPV各亚型的感染率; 并按年龄分为五组,探讨各组间HPV的感染状况。结果 HPV阳性标本805例(22%,805/3 664),其中单一感染和多重感染均可见。单一型较常见分别为16,52,43,58和56型; 双重感染较常见分别为16+52,16+33和43+52型。经统计,各年龄组间HPV感染率差异有统计学显著性意义(χ2=27.08,P＜0.01),以第一组(＞25岁)、第二组(25～34岁)和第五组(＜55岁)为HPV感染的高发组。结论 汕头地区女性HPV感染以16,52,43,58和56型多见,且＜35岁及＞55岁为该地区HPV感染的高发人群。研制针对以上型别的疫苗有利于减少该地女性HPV的感染率和预防宫颈癌的发生。
Abstract:
Objective To review the HPV infection status ofthe females in Shantou in the past years.Methods 3 664specimens of cervical exfoliated cells of the female patients with gynecologicaldisease from 2013 to 2014 were selected to amplified HPV gene and conducted genetypes detection.The infection rate and various subtypes of HPV were analyzed.All these patients were divided into 5 groups according to their ages and the infection status of each group were also discussed.Results 805 patients were infected with HPV(22%,805/3 664).The single infection type and the mixed infection type were both visible,HPV-16 was the most common single infection type,followed by subtypes HPV-52,43,58 and 56.HPV16+52 was the most common mixed infection type,followed by HPV16+33 and HPV43+52.The infection rates of the each group were differences(χ2=27.08,P＜0.01),No.1(＞25),No.2(25～34)and No.5 group(＜55)were the high-risk groups ofHPV infection.Conclusion The main genotypes of these women whose infection with HPV were HPV-16,52,43,58 and 56 in Shantou region,respectively.Thefemales aged less than 35 years old and more than 55 years old both had high-risk for HPV infection.It has important significance to developed the vaccines which can efficiently prevent HPV-16,52,43,58,56 and reduce the cervical cancer incidence.

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备注/Memo

备注/Memo:
作者简介:王 妍(1983-),女,硕士研究生,主管技师,Tel:13536816856,E-mail:laylawon1125@163.com。
更新日期/Last Update: 2015-08-10