[1]周 静,陶 丽.西安市第四医院2012～2014年多重耐药菌的临床分布分析[J].现代检验医学杂志,2016,31(02):127-129.[doi:10.3969/j.issn.1671-7414.2016.02.038]
　ZHOU Jing,TAO Li.Analysis of Clinical Distribution of Multi Drug Resistant from 2012 to 2014[J].Journal of Modern Laboratory Medicine,2016,31(02):127-129.[doi:10.3969/j.issn.1671-7414.2016.02.038]
点击复制

西安市第四医院2012～2014年多重耐药菌的临床分布分析()
分享到：

《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年02期
页码:
127-129
栏目:
检验与临床
出版日期:
2016-06-01

文章信息/Info

Title:
Analysis of Clinical Distribution of Multi Drug Resistant from 2012 to 2014
作者:
周 静; 陶 丽
西安市第四医院控感科,西安 710004
Author(s):
ZHOU Jing; TAO Li
Xi'an Fourth Hospital,Xi'an 710004,China
关键词:
多重耐药菌;  临床分布
分类号:
R446.5
DOI:
10.3969/j.issn.1671-7414.2016.02.038
文献标志码:
A
摘要:
目的 分析某院住院患者多重耐药菌(MDROs)的临床分布特征,为MDROs的预防与控制提供依据。方法 回顾性分析2012年1月～2014年12月该院MDROs的临床分布情况。结果 共监测住院病例116 316份,发生MDROs感染434例,感染率为0.37%,2014年(0.30%)与2012年(0.38%)比较,差异有统计学意义(χ2=3.91,P<0.05); 检出前五位多重耐药菌为大肠埃希菌(45.62%)、金黄色葡萄球菌(20.28%)、鲍曼不动杆菌(15.90%)、肺炎克雷伯菌(9.68%)和铜绿假单胞菌(8.53%); 前三位标本来源主要为痰液(58.29%)、尿液(19.59%)和其他分泌物标本(15.90%); 前三位科室为重症医学科(25.58%)、呼吸内科(23.04%)、泌尿外科(7.60%)。结论 不同科室MDROs临床分布不同,加强监测同时采取干预措施,能有效预防和控制MDROs感染的发生。
Abstract:
Objective To analyze the characteristics of clinical distribution of multidrug -resistant organisms(MDROs)in a hospital so as to put forward the intervention measures to prevent and control the MDROs infections.Methods Clinical distribution of MDROs was that isolated from patients in a hospital from Jan 1,2012 to Dec 31,2014 were analyzed retrospectively.Results 116 316 patients were admitted in this hospital of which 434(0.37%)cases of MDROs infections developed.The incidence of MDROs infectionswas 0.38% in 2012,0.30% in 2014,and there wasstatistically significant difference(χ2=3.91,P<0.05).The top five pathogens were Escherichia coli(45.62%),Staphylococcus aureus(20.28%),Bauman Acinetobacter(15.90%),Klebsiella Pneumoniae(9.68%),andPseudomonas aeruginosa(8.53%),respectively.The top three sample types were sputum(58.29%),urine(19.59%),and other secretions(15.90%),respectively.The top three departments were critical medical department(25.58%),respiratory department of internal medicine(23.04%)and department of urology(7.60%),respectively.Conclusion The clinical distribution characteristics of MDROs in different departments was different.It is an effective way to strengthen the monitoring of the MDROs infections and implement the intervention measures so as to prevent and control the MDROs infections.

参考文献/References:

[1] Federico P,Hujer AM,Hujer KM,et al.Global challenge of multidrug-resistant Acinetobacter baumannii[J].Antimicrob Agents Chemother,2007,51(10):3471-3484.
[2] 祝丙华,邢玉斌,王韶辉,等.医院感染多药耐药菌的分布及干预效果评价[J].中华医院感染学杂志,2014,24(11):2610-2612. Zhu BH,Xing YB,Wang SH,et al.Pathogen distribution of multi drug resistant bacteria infection and evaluation of intervention[J].Chinese Journal of Nosocomiology,2014,24(11):2610-2612.
[3] 黄 勋,邓子德,倪语星,等.多重耐药菌医院感染预防与控制中国专家共识[J].中国感染控制杂志,2015,14(1):1-9. Huang X,Deng ZD,Ni YX,et al.Chinese experts'consensus on prevention and control of multidrug resistance organism healthcare-associated infection[J].Chinese Journal of Infection Control,2015,14(1):1-9.
[4] 张河林,赵飞俊,何凤屏,等.2 527株临床分离病原菌的耐药性分析[J].现代检验医学杂志,2015,30(2):87-90. Zhang HL,Zhao FJ,He FP,et al.Drug resistance spectrum analysis of 2 527 clinical isolates of bacteria[J].Journal of Modern Laboratory Medicine,2015,30(2):87-90.
[5] 周 杰,周俊卿,封继宏,等.多药耐药菌感染目标性监测分析研究[J].中华医院感染学杂志,2014,24(21):5269-5270. Zhou J,Zhou JQ,Feng JH,et al.Targeted monitoring of multidrug-resistant bacteria infections[J].Chinese Journal of Nosocomiology,2014,24(21):5269-5270.
[6] Klevens RM,Edwards JR,RC Jr,et al.Targeted versus universal decolonization to prevent ICU infection[J].N Engl J Med,2013,368(24):2255-2265.
[7] 唐石伏,刘春明,朱胜波,等.2010年～2012年柳州地区常见多重耐药菌临床分布特征分析[J].现代检验医学杂志,2013,28(6):154-155,159. Tang SF,Liu CM,Zhu SB,et al.Analysis of clinical distribution characteristics of common MDROS isolated in Liuzhou district from 2010 to 2012[J].Journal of Modern Laboratory Medicine,2013,28(6):154-155,159.
[8] Barnes SL,Morgan DJ,Harris AD,et al.Preventing the transmission of multidrug-resistant organisms:modeling the relative importance of hand hygiene and environmental cleaning interventions[J].Infect Control Hosp Epidemiol,2014,35(9):1156-1162.

备注/Memo

备注/Memo:
作者简介:周 静(1980-),女,硕士研究生,主治医师,从事医院感染管理工作,Tel:029-87480735,E-mail:375145512@qq.com。
更新日期/Last Update: 2016-02-20