[1]袁平宗,汤雪彪,王小龙,等.革兰氏阴性细菌感染患者血清内毒素检测临床探讨[J].现代检验医学杂志,2016,31(06):121-123.[doi:10.3969/j.issn.1671-7414.2016.06.035]
　Detection of Serum Endotoxin in Patients with Gram Negative Bacterial Infection.Detection of Serum Endotoxin in Patients with Gram Negative Bacterial Infection[J].Journal of Modern Laboratory Medicine,2016,31(06):121-123.[doi:10.3969/j.issn.1671-7414.2016.06.035]
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革兰氏阴性细菌感染患者血清内毒素检测临床探讨()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年06期
页码:
121-123
栏目:
研究简报·实验技术
出版日期:
2016-12-20

文章信息/Info

Title:
Detection of Serum Endotoxin in Patients with Gram Negative Bacterial Infection
作者:
袁平宗; 汤雪彪; 王小龙; 李传达
内江市第二人民医院检验科,四川内江 641100
Author(s):
Detection of Serum Endotoxin in Patients with Gram Negative Bacterial Infection
Department of Clinical Laboratory, the Second People's Hospital of Neijiang,Sichuan Neijiang 641100,China
关键词:
细菌内毒素;  革兰氏阴性菌;  细菌培养;  感染性疾病
分类号:
R378; R446.5
DOI:
10.3969/j.issn.1671-7414.2016.06.035
文献标志码:
A
摘要:
目的 探讨细菌内毒素(ET)检测在革兰氏阴性细菌感染性疾病患者中的临床应用。方法 对200例送细菌培养检测的患者,同时抽取血标本,采用鲎试剂动态浊度法对其行ET水平检测。结果 送检标本中有112例ET水平>0.030 EU/ml; 39例患者标本培养检出细菌,革兰氏阴性菌(G-)24例,ET检测结果0.264±0.109 EU/ml,均>0.115 EU/ml; 革兰氏阳性菌(G+)15例,ET结果0.023±0.025 EU/ml,两组比较,差异有统计学意义(t=28.23,P<0.05)。结论 血液ET升高与G-菌感染有相关性,患者先行血ET检测有利于对患者G-菌感染早期诊断和治疗提供理论依据。
Abstract:
Objective To investigate the clinical application of bacterial ndotoxin(ET)in the patients with gram-negative bacterial infections.Methods 200 ases sent for bacterial culture for the detection of patients.At the same time,blood samples were taken by kineticturbidimetric technique with limulus reagent on the line ET levels were measured.Results Specimens in 112 cases of ET level greater than0.030 EU/ml.Bacteria was detected in 39 cases of patients were culture and gram negative bacteria(G-)in 24 cases,ET test results 0.264±0.109 EU/ml,were greater than 0.115 EU/ml; gram positive bacteria(G+)in 15 cases,ET results 0.023±0.025 EU/ml,two group comparison,the difference had statisticalsignificance(t=28.23,P<0.05).Conclusion Blood ETincrease is correlated with G- bacteria infection,first with the detection of ET have to on patients with G- bacteria infection in early diagnosis and treatment and provide a theoretical basis.

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备注/Memo

备注/Memo:
基金项目:国际医学研究基金(亚洲区)临床微生物学专项基金项目(项目编号:CNSC-J2011-A3300)。 作者简介:袁平宗(1967-),男,本科,副主任技师,主要从事临床生化、实验室管理,E-mail:YPZ123@126.com。 通讯作者:李传达,E-mail:LLCCDD@126.com。
更新日期/Last Update: 2016-12-20