[1]归巧娣,刘文康,苍金荣,等.2013～2015年陕西省细菌耐药监测网血培养革兰阳性病原菌变迁及耐药性分析[J].现代检验医学杂志,2017,32(02):89-91.[doi:10.3969/j.issn.1671-7414.2017.02.024]
　GUI Qiao-di,LIU Wen-kang,CANG Jin-rong,et al.Drug Resistance of Pathogens in Blood Culture Specimens in Shaanxi Antimicrobial Resistant Investigation Net from 2013 to 2015[J].Journal of Modern Laboratory Medicine,2017,32(02):89-91.[doi:10.3969/j.issn.1671-7414.2017.02.024]
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2013～2015年陕西省细菌耐药监测网血培养革兰阳性病原菌变迁及耐药性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年02期
页码:
89-91
栏目:
论著
出版日期:
2017-03-25

文章信息/Info

Title:
Drug Resistance of Pathogens in Blood Culture Specimens in Shaanxi Antimicrobial Resistant Investigation Net from 2013 to 2015
文章编号:
1671-7414(2017)02-089-03
作者:
归巧娣; 刘文康; 苍金荣; 宫艳艳; 任健康
陕西省人民医院检验科,西安 710068
Author(s):
GUI Qiao-di; LIU Wen-kang; CANG Jin-rong; GONG Yan-yan; REN Jian-kang
Department of Clinical Laboratory,Shaanxi Provincial People'sHospital,Xi'an 710068,China
关键词:
血培养;  革兰阳性病原菌;  耐药性
分类号:
R378; R446.5
DOI:
10.3969/j.issn.1671-7414.2017.02.024
文献标志码:
A
摘要:
目的 探讨2013～2015年陕西省细菌耐药监测网血培养革兰阳性病原菌变迁及耐药性分析。方法 收集2013～2015年陕西省细菌耐药监测网各成员单位革兰阳性菌引起的血流感染数据,依据CLSI2014年标准,用WHONET 5.6软件进行数据分析。结果 2013～2015年血培养共收集8 224株革兰阳性菌,前五位的病原菌分别是:表皮葡萄球菌、溶血葡萄球菌、人葡萄球菌、金黄色葡萄球菌和屎肠球菌。耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林表皮葡萄球菌(MRSE)的检出率分别为33.9%～54.9%和82.1%～88.6%,未发现万古霉素、利奈唑胺和替考拉宁耐药的葡萄球菌。耐万古霉素屎肠球菌发生率0.9%～2%。结论 2013～2015年血培养阳性菌的组成变化不大,MRSA和MRSE的检出率有逐年下降的趋势,病原菌对临床常用抗菌药物有较高的耐药性。应充分利用该地细菌耐药监测结果进行监督管理,促进抗菌药物合理应用。
Abstract:
Objective To explore the Gram-positive bacterial drug resistance in blood culture in 2013 to 2015 from the members of Antimicrobial Resistant Investigation Net of Shaanxi province,and guide the clinicianstouse antimicrobial drugs rationally.Methods All the objective bacterial isolates were collected and identified susceptibility date by software WHONET 5.6.Results 8 824 Gram-positive bacterial isolates and their antibacterial susceptibilitydata were collected.The top five populations of Gram-positive bacterial isolates were Staphylococcus epidermidis,Staphylococcus hominis,Staphylococcus haemolyticus,Staphylococcus aureus and Enterococcus feacium.The isolating rates of methicillin-resistant Staphylococcus aureus(MRSA)and methicillin-resistant coagulase negative Staphylococcus(MRCNS)were 33.9～54.9% and 72.1～88.6% respectively.No vancomycin,Linezolid and teicoplanin resistant Staphylococcus isolates were found.There were 0.9～2% E.faecium vancomycin-resistant isolates.Conclusion The composition of blood culture from 2013 to 2015 was not changed,The rate of MRSA and MRSE showed downward trend.But it wassevere that the situation of bacterial drug resistance in blood culture in Shaanxi province.Should fully use bacterial drug resistance surveillance resultsfor supervision and administration,and take effective measures for controllingthe spread of resistant isolates.

参考文献/References:

[1] 刘彩林,孙自镛,朱旭慧,等.2001～2010年血培养病原菌变迁及耐药性分析[J]中华医院感染学杂志,2012,22(3):624-626. Liu CL,Sun ZY,Zhu XH,et al.Distribution and drug resistance of pathogens in blood culture specimens from 2001 to 2010[J].Chinese Journal of Nosocomiology,2012,22(3):624-626.
[2] 归巧娣,苍金荣,刘 英.2010～2012年血培养病原菌分布及耐药性分析[J].现代检验医学杂志,2013,28(5):165-166. Gui QD,Cang JR,Liu Y.Distribution and drug resistance of pathogens in blood culture specimens from 2010 to 2012[J].J Mod Lab Med,2013,28(5):165-166.
[3] 刘耀婷,周庭银.6505份血培养病原菌分布及耐药分析[J].现代检验医学杂志,2012,27(3):94-97. Liu YT,Zhou TY.Distribution and drug resistance analysis of pathogen isolated from 6 505 blood culture specimens[J].J Mod Lab Med,2012,27(3):94-97.

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备注/Memo

备注/Memo:

作者简介:归巧娣(1978-),女,副主任医师,硕士研究生,主要从事临床微生物和细菌耐药研究,Tel:13649200365,E-mail:gqd1212@126.com。
更新日期/Last Update: 2017-04-10