[1]作者简介:李晓征(1970-),女,检验医学本科学历,等.新疆维汉民族人类白细胞抗原B27阳性表达分布特点的研究[J].现代检验医学杂志,2017,32(04):107-109.[doi:10.3969/j.issn.1671-7414.2017.04.030]
　LI Xiao-zheng,BAI Yu-sheng,XIANG Xin,et al.Study on the Distribution of Human Leukocyte Antigen B27 Positive Expression in Uygur and Han Nationalities in Xinjiang[J].Journal of Modern Laboratory Medicine,2017,32(04):107-109.[doi:10.3969/j.issn.1671-7414.2017.04.030]
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新疆维汉民族人类白细胞抗原B27阳性表达分布特点的研究()

《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年04期
页码:
107-109
栏目:
论著
出版日期:
2017-07-25

文章信息/Info

Title:
Study on the Distribution of Human Leukocyte Antigen B27 Positive Expression in Uygur and Han Nationalities in Xinjiang
文章编号:
1671-7414(2017)04-107-03
作者:
作者简介:李晓征(1970-),女,检验医学本科学历,学士学位,副主任技师,主要从事血液病实验室诊断及临床基础检验工作,E-mail:lxz0201@163.com。 通讯作者:白玉盛(1967-),男,研究生同等学历,博士生导师,主任医师,主要从事中西医结合血液病基础与临床研究,E-mail:bysh0606@163.com。
新疆医科大学附属中医医院a.临床检验中心; b.血液科,乌鲁木齐 830000
Author(s):
LI Xiao-zhenga,BAI Yu-shengb,XIANG Xina,GULIZHATIa,YANG Xuea,ZHU Jiang-lia
a.Centre of Clinical Laboratory; b.Hematology Department,Affiliated Hospital of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi 830000,China
关键词:
人类白细胞抗原B27;  维吾尔族;  汉族;  年龄段;  性别
分类号:
R392.11
DOI:
10.3969/j.issn.1671-7414.2017.04.030
文献标志码:
A
摘要:
目的 研究新疆维吾尔族与汉族人类白细胞抗原B27(HLA-B27)阳性表达的水平在不同年龄段、不同性别之间的关系,探讨HLA-B27在不同民族中的临床诊断价值。方法 收集了2013年1月～2016年11月31日门诊及住院期间使用流式细胞法检测的维吾尔族与汉族HLA-B27阳性表达的患者1 416例,其中维吾尔族369例,汉族1 047例。结果 两独立样本的t检验显示,维吾尔族与汉族HLA-B27阳性表达的含量差异具有统计学意义(165.22±8.262 vs 163.99±8.113,t=2.479,P=0.013),维吾尔族的含量高于汉族。在男性中,维吾尔族与汉族HLA-B27阳性表达的含量差异具有统计学意义(165.40±8.237 vs 163.99±8.164,t=2.187,P=0.029),维吾尔族男性的含量高于汉族。在41～60岁,>60岁年龄段中,维吾尔族的HLA-B27阳性表达的含量均高于汉族(166.18±7.650 vs 164.53±8.018,t=2.215,P=0.027; 171.63±8.134 vs 167.40±9.469,t=2.126,P=0.035)。在女性中,以及在<20岁,21～40岁年龄段中,维吾尔族与汉族HLA-B27阳性表达的含量差异无统计学意义(t=-0.029～1.257,均P>0.05)。结论 该调查显示在HLA-B27阳性表达的人群中,其含量维吾尔族高于汉族。HLA-B27阳性表达的含量具有种族差异性。
Abstract:
Objective To study the relationship between thepositive expression of human leukocyte antigen B27(HLA-B27)in different agegroups and genders in Uygur and Han nationality in Xinjiang,and explore the clinical value of HLA-B27 in different ethnic groups.Methods From January 2013 to November 2016,1 416 cases of Uygur and Han patients with positive expression of HLA-B27 were detected by flow cytometry.There were 369 cases of Uygur and 1 047 cases of Han.Results Independent samples t-test showed that the positive expression of HLA-B27 inUygur and Han population was statistically significant(165.22±8.262 vs 163.99±8.113,t=2.479,P=0.013).In male,there was a significant differencein the positive expression of HLA-B27 between Uygur and Han population(165.40±8.237 vs 163.99±8.164,t=2.187,P=0.029).In the age of 41～60 yearsold and >60 years old,the positive expression of HLA-B27 in Uygur was higherthan that in Han nationality(166.18±7.650 vs 164.53±8.018,t=2.215,P=0.027; 171.63&#177;8.134 vs 167.40&#177;9.469,t=2.126,P= 0.035).There was no significant difference in the positive expression of HLA-B27 between Uygur and Han nationality in women,as well as in the age of 20 years and 21～40 years(t=-0.029～1.257,all P>0.05).Conclusion The investigation showed that the positive expression of HLA-B27 in Uygur was higherthan that in Han nationality.The content of HLA-B27 positive expression has racial difference.

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备注/Memo

备注/Memo:
作者简介:李晓征(1970-),女,检验医学本科学历,学士学位,副主任技师,主要从事血液病实验室诊断及临床基础检验工作,E-mail:lxz0201@163.com。 通讯作者:白玉盛(1967-),男,研究生同等学历,博士生导师,主任医师,主要从事中西医结合血液病基础与临床研究,E-mail:bysh0606@163.com。
更新日期/Last Update: 1900-01-01