[1]林丽云a,杜 宇b,罗奇智a,等.LHD和RDW在缺铁性贫血患儿诊疗中的应用价值[J].现代检验医学杂志,2017,32(04):113-115,118.[doi:10.3969/j.issn.1671-7414.2017.04.032]
　LIN Li-yun,DU Yu,LUO Qi-zhi,et al.Apply Value of LHD and RDW in Diagnosis and Treatment of Children with Iron Deficiency Anemia[J].Journal of Modern Laboratory Medicine,2017,32(04):113-115,118.[doi:10.3969/j.issn.1671-7414.2017.04.032]
点击复制

LHD和RDW在缺铁性贫血患儿诊疗中的应用价值()
分享到：

《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年04期
页码:
113-115,118
栏目:
论著
出版日期:
2017-07-25

文章信息/Info

Title:
Apply Value of LHD and RDW in Diagnosis and Treatment of Children with Iron Deficiency Anemia
文章编号:
1671-7414(2017)04-113-04
作者:
林丽云a; 杜 宇b; 罗奇智a; 何萍萍a
深圳市龙岗区第二人民医院 a.检验科; b.儿科,广东深圳 518112
Author(s):
LIN Li-yun1; DU Yu2; LUO Qi-zhi1; HE Ping-ping1
a.Department of Clinical Laboratory; b.Department of Pediatric, the Second People's Hospital of Shenzhen Longgang,Guangdong Shenzhen 518112,China
关键词:
低血红蛋白浓度;  红细胞体积分布宽度;  缺铁性贫血;  儿童;  价值
分类号:
R556.3; R446.111
DOI:
10.3969/j.issn.1671-7414.2017.04.032
文献标志码:
A
摘要:
目的 探讨低血红蛋白浓度(1ow haemoglobin density,LHD)和红细胞体积分布宽度(red blood cell volume distribution width,RDW)在缺铁性贫血(iron-deficiency anemia,IDA)患儿诊疗中的应用价值。方法 收集2016年2月～2017年5月深圳市龙岗区第二人民医院确诊的缺铁性贫血患儿86例为IDA组,同时选择同期健康儿童120例为对照组,分别检测IDA患儿治疗前后和对照组儿童血常规,依据平均血红蛋白浓度(MCHC)计算出LHD,并对结果进行统计分析。结果 120例健康儿童外周血中LHD值为2.74%±0.90%,其中男童为3.07%±0.81%,女童为2.26%±0.69%,男童高于女童,两者之间差异有统计学意义(t=3.815,P<0.05); RDW值为12.37%±2.84%,其中男童为12.09%±2.80%,女童为12.56%±2.87%,两者之间差异无统计学意义(t=0.517,P>0.05); 86例IDA患儿治疗前外周血中LHD和RDW值分别为30.67%±20.12%和16.62%±3.27%,明显高于对照组,两者之间差异有统计学意义(t=4.025～19.650,P<0.05～0.01),其中男、女患儿两者之间差异无统计学意义(t=0.761～0.917,P>0.05),治疗后LHD和RDW值分别为10.65%±8.92%和14.02%±2.93%,明显低于治疗前,两者之间差异有统计学意义(t=2.912～9.675,P<0.05)。结论 IDA患儿治疗前血液中的LHD和RDW值明显升高,治疗后明显下降,LHD和RDW值对IDA患儿诊断和治疗动态监测有一定的应用价值,值得推广应用。
Abstract:
Objective To investigate the low hemoglobin density(low haemoglobin density,LHD)and red blood cell volume distribution width(red blood cell volume distribution width,RDW)in iron deficiency anemia(iron-deficiency anemia,IDA)in children with the value of diagnosis and treatment.Methods From February 2016 to May 2017,in the Second People's Hospital of Longgang District in Shenzhen City,86 cases of children with iron deficiency anemia for IDA group,and 120 cases of healthy children(as the control group)at the same time were confirmed.Blood routine of children with IDA were detected before and after treatment hemoglobin concentration and theresults were analyzed statistically.Results 120 cases of healthy children in the peripheral blood LHD value was 2.74%±0.90% and theboy was 3.07%±0.81%,higher than that of 2.26%±0.69% of the girls.Betweenthem,there was statistically significant difference(t=3.815,P<0.05).The value of RDW was 12.37%±2.84%,12.09%±2.80% for the boys and 12.56%±2.87% for the girls,there was no statistically significant difference between the them(t=0.517,P>0.517).Before treatment,86 cases of children with IDA LHD and RDW values in peripheral blood were 30.67%±20.12% and 16.62%±3.27%,significantly higher than the control group,the difference was statistically significant between(t=4.025～4.025,P<0.05～0.01),and there was no statistically significant difference between male and female children(t=0.761～0.917,P>0.05).After treatment LHD and RDW values were 10.65%±8.92% and 14.02%±2.93%,significantlylower than before the treatment,between them was statistically significant difference(t=2.912～9.675,P<0.05).Conclusion Children with iron deficiency anemia treatment before theLHD and RDW values significantly elevated in the blood,significantly decreasedafter treatment,the LHD and RDW values for diagnosis and treatment of childrenwith iron deficiency anemia dynamic monitoring has certain application value,worthy of popularization and application.

参考文献/References:

[1] 简咏芬,周少雄,潘永红,等.网织红细胞参数用于鉴别诊断地中海贫血与缺铁性贫血的价值[J].医学检验与临床,2016,27(2):64-65,80,85. Jian YF,Zhou SX,Pan YH,et al.The value of reticulocyte parameters in differential diagnosis between thalassaemia and iron deficiency anemia[J].Medical Laboratory Science and Clinical,2014,27(2):64-65,80,85.
[2] 刘晓红,高素红,王佳楣,等.亚临床甲状腺异常对妊娠结局的影响[J].中华围产医学杂志,2012,15(11):696-700. Liu XH,Gao SH,Wang JM,et al.Effects of abnormal thyroid thyroidon pregnancy outcomes[J].Chinese Journal of Perinatal Medicine,2015,15(11):696-700.
[3] 张之南.血液病诊断及疗效标准[M].2版.北京:科学出版社,1998:10-15. Zhang ZN.Diagnostic and therapeutic criteria of hematopathy[M].2th Ed.Beijing:Science Press,1998:10-15.
[4] 张丽霞,陆 琳,周 芸,等.南京地区低血红蛋白密度参考区间的建立及其在缺铁性贫血中的应用[J].现代检验医学杂志,2012,27(6):23-24,29. Zhang LX,Lu L,Zhou Y,et al.Establishment of reference range forlow hemoglobin density in nanjing and its clinical utility in the diagnosis ofiron deficiency anemia[J].Journal of Modern Laboratory Medicine,2012,27(6):23-24,29.
[5] 赵惠君.儿童缺铁和缺铁性贫血的防治[J].实用儿科临床杂志,2012,27(3):163-165. Zhao HJ.Prevention and treatment of childhood iron deficiency andiron deficiency anemia[J].Journal of Applied Clinical Pediatrics,2012,27(3):163-165.
[6] 童丽春,柴素萍,虞文斌.硫酸亚铁缓释片加食补治疗孕妇缺铁性贫血的临床观察[J].上海预防医学,2016,28(3):206-207. Tong LC,Chai SP,Yu WB.Clinical observation of iron deficiency anemia in pregnant women with ferrous sulfate[J].Shanghai Journal of PreventiveMedicine,2016,28(3):206-207.
[7] 廖志梅,郝国平.6月～36月婴幼儿缺铁性贫血相关因素分析[J].中国医疗前沿,2011,6(23):43-45. Liao ZM,Hao GP.The related factors of iron deficiency anemia in infants aged 6 to 30 months[J].National Medical Frontiersof China,2011,6(23):43-45.
[8] Urrechaga E,Unceta M,Borque L,et al.Low hemoglobin density potentialmarker of iron availability[J].Int Jnt Lab Hern,2012,34(1):47-51.
[9] 中国儿童铁缺乏症流行病学调查协作组.中国7个月～7岁儿童铁缺乏症流行病学的调查研究[J].中华儿科杂志,2004,42(12):886-891. Collaborative Study Group for the Epidemological Su-rvey of Iron Deficiency in Children in China.Prevalence in children aged 7 months to 7 years inChina[J].Chinese Journal of Pediatrics,2004,42(12):886-891.
[10] 赵耀华,杨小影.红细胞体积分布宽度在农村儿童铁缺乏症筛查中的应用[J].国际检验医学杂志,2014,35(7):925-926. Zhao YH,Yang XY.The distribution of red blood cell volume in rural children's iron deficiency diseases[J].International Journal of Laboratory Medicine,2014,35(7):925-926.
[11] 李秀锋,宋金凤,邢 莹,等.低血红蛋白密度在铁缺乏筛查及贫血类型鉴别诊断中的临床应用探讨[J].中华医学杂志,2014,94(44):3506-3509. Li XF,Song JF,Xing Y,et al.Clinical application of low hemoglobin density in screening for of iron deficiency and the differential diagnosis of anemia[J].National Medical Journal of China,2014,94(44):3506-3509.
[12] 孙秀山,颜 洁,管泽琴.血常规检测对缺铁性贫血和地中海贫血鉴别诊断中的应用[J].四川医学,2013,34(3):440-441. Sun XS,Yan J,Guan ZQ.Blood routine detection of iron deficiency anemiaand the application of the diagnosis of thalassemia[J].Sichuan Medical Journal,2013,34(3):440-441.
[13] Urrechaga E.The new mature red cell parameter,lo-w haemoglobin density of the Beckman-Coulter LH750:clinical utility in the diagnosis of iron deficiency[J].Int J Lab Hematol,2010,32(1pt1):144-150.
[14] 何金泉,吴彩明,李国强.广东虎门地区健康人群低血红蛋白密度(LHD%)参考区间的建立和临床应用[J].现代检验医学杂志,2017,32(2):86-88,91. He JQ,Wu CM,Li GQ.Building the reference renge of low hemoglobin density(LHD%)of healthy population in humen district of Guangdong and discuss its clinical application value[J].Journal of Modern Laboratory Medicine,2017,32(2):86-88,91.
[15] 刘秀瑰.红细胞体积分布宽度在儿童铁缺乏症筛查中的应用研究[J].实用检验医师杂志,2014,6(4):227-229. Liu XG.The research of RDW in screening of children with iron deficiency[J].Chinese Journal of Clinical Pathologist,2014,6(4):227-229.
[16] 况 凡,杨 琼,吴 皖.微量元素铁联合MCV,RDW对儿童缺铁性贫血的临床意义[J].广东微量元素科学,2013,20(11):10-12. Kuang F,Yang Q,Wu W.Trace elements iron combined with MCV,clinical significance of RDW in children with iron deficiency anemia[J].Guangdong Trace Elements Science,2013,20(11):10-12.

相似文献/References:

[1]李家明a,胡昌玲b,杨德娟b,等.四川攀枝花地区成年健康体检人群红细胞指数及体积分布宽度参考区间的建立[J].现代检验医学杂志,2018,33(05):98.[doi:10.3969/j.issn.1671-7414.2018.05.026]
　LI Jia-minga,HU Chang-lingb,YANG De-juanb,et al.Establishment of Reference Intervals for RBC Index and Volume Distribution Width of Adult Health Check-up Population in Panzhihua District of Sichuan[J].Journal of Modern Laboratory Medicine,2018,33(04):98.[doi:10.3969/j.issn.1671-7414.2018.05.026]
[2]毛彤瑶,郭佳培,李 宁,等.肾性贫血患者外周血红细胞参数与微炎症指标相关性分析[J].现代检验医学杂志,2018,33(06):146.[doi:10.3969/j.issn.1671-7414.2018.06.038]
　MAO Tong-yao,GUO Jia-pei,LI Ning,et al.Detection of Erythrocyte Parameters in Patients with Renal Anemia and Its Correlation with the Index of Microinflammation[J].Journal of Modern Laboratory Medicine,2018,33(04):146.[doi:10.3969/j.issn.1671-7414.2018.06.038]

备注/Memo

备注/Memo:
基金项目:深圳市龙岗区科技局基金项目(项目编号:20170403142337440)。 作者简介:林丽云(1983-),女,本科,学士,主管技师,主要从事临检和生化免疫检验工作,E-mail:linliyun1983_1@163.com。
更新日期/Last Update: 1900-01-01