[1]杜 洁a,朱 娜b,李红艳a,等.幽门螺杆菌感染对慢性阻塞性肺疾病血气分析及肺功能的影响[J].现代检验医学杂志,2017,32(06):99-101.[doi:10.3969/j.issn.1671-7414.2017.06.001]
　DU Jiea,ZHU Nab,LI Hong-yana,et al.Effect of Helicobacter Pylori Infection on Blood Gas Analysis and Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease[J].Journal of Modern Laboratory Medicine,2017,32(06):99-101.[doi:10.3969/j.issn.1671-7414.2017.06.001]
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幽门螺杆菌感染对慢性阻塞性肺疾病血气分析及肺功能的影响()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年06期
页码:
99-101
栏目:
论著
出版日期:
2017-12-25

文章信息/Info

Title:
Effect of Helicobacter Pylori Infection on Blood Gas Analysis and Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease
文章编号:
1671-7414(2017)06-099-03
作者:
杜 洁a; 朱 娜b; 李红艳a; 隋永杰a; 张永庆c
陕西省人民医院a.健康体检中心; b.科研处; c.呼吸内一科,西安 710068
Author(s):
DU Jiea; ZHU Nab; LI Hong-yana; SUI Yong-jiea; ZHANG Yong-qingc
a.Physical Examination Center; b.Department of Research; c.Department of the First Respiratory Medicine,Shaanxi Provincial People's Hospital,Xi'an 710068,China
关键词:
慢性阻塞性肺疾病;  幽门螺杆菌;  血气分析;  肺功能
分类号:
R378.2; R563
DOI:
10.3969/j.issn.1671-7414.2017.06.001
文献标志码:
A
摘要:
目的 分析幽门螺杆菌(Hp)感染对慢性阻塞性肺疾病(COPD)血气分析及肺功能的影响。方法 回顾性分析2015年8月～2016年10月收治的130例Hp感染阳性的COPD患者(Hp阳性组)和130例Hp感染阴性的COPD患者(Hp阴性组)为研究对象,比较两组患者的血气分析和肺功能情况。结果 血气分析结果显示Hp阳性组的血氧分压(PaO2)水平62.5±7.4 mmHg,血氧饱和度(SaO2)86.3%±9.6%,低于Hp阴性组78.6±10.2 mmHg,92.8%±2.9%,而Hp阳性组PaCO2的水平(56.3±10.6 mmHg)高于Hp阴性组(43.2±11.5 mmHg),差异均具有统计学意义(t=14.57,7.39,9.55,均P<0.01); 肺功能结果示Hp阳性组的第1 s最大呼气量(FEV1)1.56±0.48 L,第1 s用力呼气量占用力肺活量比值(FEV1/FVC)(52.8%±7.4%)及FEV1占预计值比值(FEV1/预计值)49.1%±6.2%测定低于HP阴性组(1.74±0.32 L,65.9%±5.3%,58.2%±5.6%),差异均具有统计学意义(t=3.56,12.42,16.41,均P<0.01)。结论 Hp感染与COPD关系密切,可能是参与并加重COPD疾病的重要因素。
Abstract:
Abstract:Objective To study the association between Helicobacter pylori(Hp)infection and chronic obstructive pulmonary disease(COPD).Methods A retrospective study was conducted in 130 patients with Hp positive COPD(Hp positive group)and 130 patients with Hp negative COPD(Hp negative group)from August 2015 to October 2016.The patients in the two groups blood gas analysis and lung function.Results The blood oxygen pressure(PaO2)level 62.5±7.4 mmHg and the oxygen saturation(SaO2)86.3%±9.6% in the Hp positive group were lower than those inthe Hp negative group(78.6±10.2 mmHg,92.8%±2.9%),(43.3±10.6 mmHg)inHp positive group was significantly higher than that in Hp negative group(43.2±11.5 mmHg),the difference was statistically significant(t=14.57,7.39 and 9.55,all P<0.01),(FEV1/FVC)(FEV1/FVC)(FEV1/FVC)and FEV1 werethe highest in the Hp-positive group(FEV1)(1.56±0.48 L),the first forcedexpiratory force(1.74±0.32 L,65.9%±5.3% and 58.2%±5.6%),the difference was statistically significant(t=3.56,12.42,16.41,all P<0.05),and the difference was statistically significant(all P<0.01).Conclusion Hp infection was closely related to COPD,which may bean important factor involved in and aggravate COPD disease.

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备注/Memo

备注/Memo:
基金会项目(项目编号:2010003)。 作者简介:杜 洁(1983-),女,硕士,主治医师,研究方向:呼吸系统疾病,E-mail:dujie123._@163.com。 通讯作者:张永庆,男,硕士,副主任医师,E-mail:zhangyongqing656@163.com。
更新日期/Last Update: 2017-12-26