[1]张志新,王 薇,何法霖,等.2014～2017年我国临床实验室HbA2和HbF检测室内质控变异系数分析[J].现代检验医学杂志,2018,33(02):143-145.[doi:10.3969/j.issn.1671-7414.2018.02.001]
　ZHANG Zhi-xin,WANG Wei,HE Fa-lin,et al.Analysis of the Coefficient of Variation for the Internal Quality Control of Hemoglobin A2 and Hemoglobin F from 2014 to 2017[J].Journal of Modern Laboratory Medicine,2018,33(02):143-145.[doi:10.3969/j.issn.1671-7414.2018.02.001]
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2014～2017年我国临床实验室HbA2和HbF检测室内质控变异系数分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年02期
页码:
143-145
栏目:
质量控制·实验室管理
出版日期:
2018-04-05

文章信息/Info

Title:
Analysis of the Coefficient of Variation for the Internal Quality Control of Hemoglobin A2 and Hemoglobin F from 2014 to 2017
文章编号:
1671-7414(2018)02-143-03
作者:
张志新; 王 薇; 何法霖; 钟 堃; 袁 帅; 刘佳丽; 杜雨轩; 王治国
北京医院 国家老年医学中心 卫生部临床检验中心/北京市临床检验工程技术研究中心,北京 100730
Author(s):
ZHANG Zhi-xin; WANG Wei; HE Fa-lin; ZHONG Kun; YUAN Shuai; LIU Jia-li; DU Yu-xuan;  WANG Zhi-guo
Beijing Hospital,National Center of Gerontology,National Center for Clinical Laboratories/Beijing Engineering Research Center of Laboratory Medicine,Beijing 100730,China
关键词:
血红蛋白A2;  血红蛋白F;  室内质控;  变异系数;  珠蛋白生成障碍性贫血
分类号:
R446
DOI:
10.3969/j.issn.1671-7414.2018.02.001
文献标志码:
A
摘要:
目的 了解2014～2017年我国临床实验室血红蛋白A2(HbA2)和血红蛋白F(HbF)检测室内质控情况。方法 收集2014～2017年参加卫生部临床检验中心室间质评参评单位回报的室内质控信息,将变异系数与1/3TEa(6.67%)和1/4TEa(5%)标准进行比较,得到满足各标准实验室的比例,进而分析我国HbA2和HbF检测的室内质控情况。按照实验室使用的仪器不同进行分组,分别计算2017年HbA2和HbF不同仪器组在两种标准下的变异系数通过率。结果 HbA2项目84%以上的实验室精密度都能达到1/3TEa的标准,达到1/4TEa标准的实验室比例略有降低(70.83%～84.47%)。HbF项目的结果除2015年外,当月和累积在控变异系数80%以上的实验室能达到1/3TEa标准,达到1/4TEa标准的实验室比例分布在68.42%～85.07%。2017年数据按仪器分组统计中,两个项目sebia capillarys 2仪器组和全自动血红蛋白分析仪伯乐VariantⅡ仪器组在两种标准下的变异系数通过率均达85%以上,精密度较好。结论 目前我国实验室HbA2和HbF检测的不精密度水平需进一步提高,尤其是HbF,实验室应继续加强室内质量控制,建立严格的室内质控制度,提高检测水平。
Abstract:
Abstract:Objective To investigate the internal quality control(IQC)of hemoglobin A2(HbA2)and hemoglobin F(HbF)from 2014 to 2017in China.Methods The results of IQC were collected fromthe laboratories which participated in external quality assessment(EQA)of National Center for Clinical Laboratories(NCCL)from 2014 to 2017,then the coefficient of variation(CV)was compared with 1/3TEa(6.67%),1/4TEa(5%).The proportion of laboratories meeting criteria were calculated to analyze IQC ofHbA2 and HbF in China.The data were grouped based on the instruments used inlaboratories,the acceptable rates of CVs of HbA2 and HbF in each group under two criteria in 2017 were calculated,respectively.Results In HbA2,more than 84% of participant laboratories met 1/3TEa criteriaand 70.83%～84.47% of laboratories met 1/4TEa criteria.In HbF except for 2015,the more than 80% laboratories whose month and cumulative CVs met 1/3TEa and 1/4TEa criteria accounted for 68.42%～85.07%,respectively.Under 1/3TEa and 1/4TEa criteria,sebia capillarys 2 instrument and fully automatic hemoglobin analyzer bole Variant Ⅱ instrument group the acceptable rates of CVsabove 85%,showed good precision for HbA2 and HbF detection.Conclusion At present,the precision level of HbA2 and HbF need to be further improved in laboratories of China,especially HbF.Laboratory should continue to strengthen the internal quality control,establish strict internal quality system to improve detection capacity.

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相似文献/References:

[1]何法霖,王 薇,钟 堃,等.血红蛋白A2和F的室间质量评价结果分析[J].现代检验医学杂志,2015,30(02):156.[doi:10.3969/j.issn.1671-7414.2015.02.050]
　HE Fa-lin,WANG Wei,ZHONG Kun,et al.External Quality Assessment of Hemoglobin A2(HbA2) and Hemoglobin F(HbF)Measurement[J].Journal of Modern Laboratory Medicine,2015,30(02):156.[doi:10.3969/j.issn.1671-7414.2015.02.050]

备注/Memo

备注/Memo:
作者简介:张志新(1988-),女,本科,检验技师,研究方向:实验室质量管理,E-mail:912690513@qq.com。 通讯作者:王治国,硕士,研究员,临床实验室质量管理,E-mail:zgwang@nccl.org.cn。
更新日期/Last Update: 2018-04-16