[1]周振忠,汪永强,袁平宗,等.外周血CRP,WBC与Nst比值单独及联合检测在儿科细菌感染性疾病中的应用价值[J].现代检验医学杂志,2018,33(03):117-119.[doi:10.3969/j.issn.1671-7414.2018.03.029]
　ZHOU Zhen-zhong,WANG Yong-qiang,YUAN Ping-zong,et al.Application Value of Single and Combined Detection of Peripheral Blood CRP,WBC and Nst Ratios in Pediatric Bacterial Infectious Diseases[J].Journal of Modern Laboratory Medicine,2018,33(03):117-119.[doi:10.3969/j.issn.1671-7414.2018.03.029]
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外周血CRP,WBC与Nst比值单独及联合检测在儿科细菌感染性疾病中的应用价值()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年03期
页码:
117-119
栏目:
论著
出版日期:
2018-07-17

文章信息/Info

Title:
Application Value of Single and Combined Detection of Peripheral Blood CRP,WBC and Nst Ratios in Pediatric Bacterial Infectious Diseases
文章编号:
1671-7414(2018)03-117-03
作者:
周振忠; 汪永强; 袁平宗; 张 丹
内江市第二人民医院检验科,四川内江 641100
Author(s):
ZHOU Zhen-zhong; WANG Yong-qiang; YUAN Ping-zong; ZHANG Dan
Department of Clinical Laboratory, the Second People's Hospital of Neijiang,Sichuan Neijiang 641000,China
关键词:
C反应蛋白;  白细胞;  中性杆状核粒细胞;  细菌感染性疾病
分类号:
R725; R446.11
DOI:
10.3969/j.issn.1671-7414.2018.03.029
文献标志码:
A
摘要:
目的 探讨外周血C反应蛋白(CRP),白细胞(WBC)和中性杆状核粒细胞(Nst)比值单独及联合检测在儿科细菌感染性疾病中的诊断价值。方法 回顾性分析内江市第二人民医院2016年7～11月临床诊断为细菌性感染患儿54例(细菌组)、非细菌性感染患儿103例(非细菌组)以及健康体检儿童56例(对照组),对所有选取对象进行CRP,WBC 以及Nst比值检测并进行统计学分析。结果 细菌组CRP,WBC和Nst比值水平分别为25.27±27.13 mg/L,(11.06±5.89)×109/L和(8.87±4.29)%,明显高于非细菌组和对照组,差异均有统计学意义(均P<0.05); 联合检测(CRP+Nst组合)ROC曲线下面积为0.955,与WBC+CRP+Nst组合ROC曲线下面积相当,优于单独检测CRP,WBC和Nst比值和其它联合检测组合指标,差异均有统计学意义(P<0.05); 联合检测(CRP+Nst组合)诊断细菌性感染的灵敏度为96.3%,高于其它单独及WBC+CRP+Nst联合检测组合指标。结论 联合检测(CRP+Nst组合)在儿科细菌感染性疾病中诊断价值较大,适合临床推广应用。
Abstract:
Abstract:Objective To investigate the diagnostic value of peripheral blood C-reactive protein(CRP),white blood cell(WBC)and neutralrod nucleus granulocyte(Nst)ratios of single and combined detection in pediatric bacterial infections disease.Methods A total of 54 children with bacterial infection(bacterial group),103 children with nonbacterialinfection(non-bacterial group)were enrolled in the Second People's Hospitalof Neijiang City from July to November in 2016,and 56 healthy children were selected as control group.CRP,WBC and Nst ratios were measured and analyzed statistically for all selected subjects.Results The levels of CRP,WBC and Nst ratios in bacterial infection group were 25.27±27.13 mg/L,(11.06±5.89)×109/L and(8.87±4.29)% respectively,which was significantly higher than that of non-bacterial and the control group(t1=3.658,3.750,5.863; t2=3.348,4.109,8.067; t3=-0.188 9,-2.153,-0.253; all P<0.05).The ROC area under curve of the combined application(CRP+Nst)was 0.955,equal to the combined application(WBC+CRP+Nst),which was higher than the single application indexs of WBC,CRP,Nst ratios and the other combinedapplications,the difference was statistically significant(P<0.05).The sensitivity of the combined application(CRP+Nst)in diagnosis of bacterial infection was 96.3%,which was higher than that of the single applications and the other combined applications.Conclusion The combined application(CRP+Nst)has a large diagnostic value in pediatric bacterial infectiousdiseases and is suitable for clinical application.

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备注/Memo

备注/Memo:
基金项目:国家高技术研究发展计划(863计划)资助项目(2014AA022304),四川省重点专科基金项目(2014-106)。 通讯作者:周振忠(1983-),男,硕士,主管检验师,研究方向为临床检验诊断学,E-mail:920761354@qq.com。
更新日期/Last Update: 2018-04-16