[1]张会品,张建春,郭兰芳.风湿热患者血清ASO滴度与HDL水平的相关性分析[J].现代检验医学杂志,2018,33(05):145-148.[doi:10.3969/j.issn.1671-7414.2018.05.040]
　ZHANG Hui-pin,ZHANG Jian-chun,GUO Lan-fang.Clinical Evaluation of High Density Lipoprotein in Rheumatic Fever[J].Journal of Modern Laboratory Medicine,2018,33(05):145-148.[doi:10.3969/j.issn.1671-7414.2018.05.040]
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风湿热患者血清ASO滴度与HDL水平的相关性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年05期
页码:
145-148
栏目:
检验与临床
出版日期:
2018-11-18

文章信息/Info

Title:
Clinical Evaluation of High Density Lipoprotein in Rheumatic Fever
文章编号:
1671-7414(2018)05-145-04
作者:
张会品1; 张建春1; 郭兰芳2
1.南京市高淳区人民医院检验科,南京 211300; 2.镇江市第四人民医院检验科,江苏镇江 212001
Author(s):
ZHANG Hui-pin1; ZHANG Jian-chun1; GUO Lan-fang2
1.Department of Clinical Laboratory, Gaochun District People's Hospital of Nanjing,Nanjing 211300,China; Department of Clinical Laboratory,the Fourth People's Hospital of Zhenjiang,Jiangsu Zhenjiang 212001,China
关键词:
高密度脂蛋白;  A群链球菌;  抗链球菌溶血素“O”;  风湿热;  相关性
分类号:
R593.21; R446.112
DOI:
10.3969/j.issn.1671-7414.2018.05.040
文献标志码:
A
摘要:
目的 探讨风湿热患者血清ASO滴度与HDL水平的相关性。方法 该研究对2014年1月～2017年9月间158例诊断为风湿热患者的临床资料进行回顾性分析,收集感染前、中、后不同时段患者的高密度脂蛋白(HDL)含量以及抗链球菌溶血素“O”(antistreptolysin-O,ASO)水平,同时收集正常对照组数据,并进行统计分析。结果 风湿热患者感染前后的ASO与HDL结果与入院前及治疗后以及正常对照组比较差异无统计学意义(P>0.05); 感染时的ASO与HDL结果与入院前、治疗后以及正常对照组比较差异有统计学意义(P<0.05)。结论 随着ASO浓度的增加HDL的结果逐渐降低,两者的相关系数r=-0.876(P<0.01)。HDL含量的变化在判断风湿热的发生发展过程中有一定的参考价值。
Abstract:
Objective To explore the dynamic changes of high-density lipoprotein(HDL)during infection in rheumatic fever patients.Methods The clinical data of 158 patients diagnosed as rheumatic fever were retrospectively analyzed.The levels of HDL and anti-streptolysin-O(ASO)levels were measured before,during and after infection.At the same time,the normal control group data were collected and statistical analysis was performed.Results It showed that the ASO and HDL resultsbefore and after infection in patients with rheumatic fever were not significantly different from those before admission and after treatment as well as in the normal control group(P>0.05).The ASO and HDL results at the time of infection were compared with pre- and post-treatment,as well as normal controls.There was a statistically significant difference between the groups(P<0.05).Conclusion With the increase of ASO concentration,theresults of HDL decreased gradually,and the correlation coefficient between themwas -0.876(P<0.01).The change of HDL content has certain reference value in judging the occurrence and development of rheumatic fever.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:镇江市社会发展指导性项目(FZ2017038)。
作者简介:张会品(1985-),女,本科,主管技师,研究方向:临床生化检验。
通讯作者:郭兰芳(1982-),女,硕士研究生,副主任技师,研究方向:临床微生物检验,E-mail:guolanfang415@163.com。
更新日期/Last Update: 2018-09-30