[1]韩 振,杨 莉.中老年人尿靛甙水平检测与血清脂类及同型半胱氨酸水平的相关性分析[J].现代检验医学杂志,2018,33(06):77-79.[doi:10.3969/j.issn.1671-7414.2018.06.020]
　HAN Zhen,YANG Li.Correlation between Uric Indicant Level and Serum Lipids and Homocysteine Levels in Middle-aged and Elderly Persons[J].Journal of Modern Laboratory Medicine,2018,33(06):77-79.[doi:10.3969/j.issn.1671-7414.2018.06.020]
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中老年人尿靛甙水平检测与血清脂类及同型半胱氨酸水平的相关性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年06期
页码:
77-79
栏目:
论著
出版日期:
2018-12-24

文章信息/Info

Title:
Correlation between Uric Indicant Level and Serum Lipids and Homocysteine Levels in Middle-aged and Elderly Persons
文章编号:
1671-7414(2018)06-077-03
作者:
韩 振1; 杨 莉2
1.烟台市莱州荣军医院,山东莱州 261400; 2.莱州市妇幼保健院,山东莱州 261400
Author(s):
HAN Zhen1; YANG Li2
1.Laizhou Rongjun Hospital of Yantai,Shandong Laizhou 261400,China; 2.Maternal and Child Health Care Hospital of Laizhou,Shandong Laizhou 261400,China
关键词:
尿靛甙;  血脂;  同型半胱氨酸
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2018.06.020
文献标志码:
A
摘要:
目的 探讨中老年人尿靛甙水平检测与血清脂类及同型半胱氨酸(HCY)水平的相关性。方法 选取莱州市50(含)岁以上健康查体者120例,随机分成实验组60例和对照组60例,实验组使用尿靛甙检测来建立个体化饮食营养指导,对照组使用普通健康教育指导,两组分别于实验前和实验结束时检测尿靛甙、胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和同型半胱氨酸(HCY)水平并进行分析。结果 实验组和对照组在实验开始前基本资料差异无统计学意义(P>0.05)。通过一年的回访和数据收集,实验结束时,实验组TC(5.47±0.85 mmol/L vs 6.38±0.71 mmol/L),TG(1.33±0.44 mmol/Lvs 1.52±0.41 mmol/L),HDL-C(1.63±0.29 mmol/L vs 1.83±0.40 mmol/L),LDL-C(3.21±0.66 mmol/L vs 3.85±0.72 mmol/L),HCY(18.6±3.17 μmol/L vs 21.7±3.08 μmol/L)和尿靛甙(72.6±13.1mg/L vs 92.7±18.5 mg/L)水平均低于对照组,差异有统计学意义(t=2.45～6.83,均P<0.05),实验组内比较,实验结束时TC(5.88±1.05 mmol/L vs 5.47±0.85 mmol/L),LDL-C(3.53±0.77 mmol/L vs 3.21±0.66 mmol/L),HCY(21.3±3.69 μmol/L vs 18.6±3.17 μmol/L)和尿靛甙(86.3±18.9 mg/L vs 72.6±13.1 mg/L)水平低于实验开始时,差异均有统计学意义(t=2.31～5.76,均P<0.05),而TG(1.38±0.73 mmol/L vs 1.33±0.44 mmol/L),HDL-C(1.75±0.37 mmol/L vs 1.63±0.29 mmol/L)在实验前后水平差异无统计学意义(t=1.22,1.09,P>0.05)。经Spearman相关性分析显示,尿靛甙水平与TC,LDL-C,HCY水平呈正相关关系(r分别为0.582～0.624,均P<0.05)。结论检测中老年人尿靛甙的水平可以有效降低血脂和同型半胱氨酸水平,从而降低中老年人患高血压、动脉粥样硬化等心血管疾病的风险。
Abstract:
Objective To explore the correlation between urinary indigo glycoside and serum lipids and homocysteine levels in middle-agedand elderly people.Methods 120 healthy subjects over 50years old were randomly divided into experimental group(60 persons)and controlgroup(60 persons)in Laizhou.Uric indicant monitoring was used to establish individualized dietary nutritional guidance for the experimental group,and the control group used general health education guidance.The levels of uric indicant,TG,HDL-C,LDL-C and HCY were analyzed before and after the experiment in both groups.Results There was no significant difference inthe basic data between the experimental group and the control group before thestart of the experiment(P>0.05).After one year's return visit and data collection,the level of TC(5.47±0.85 mmol/L vs 6.38±0.71 mmol/L),TG(1.33±0.44 mmol/L vs 1.52±0.41 mmol/L),HDL-C(1.63±0.29 mmol/L vs 1.83±0.40 mmol/L),LDL-C(3.21±0.66 mmol/L vs 3.85±0.72 mmol/L),HCY(18.6±3.17 μmol/L vs 21.7±3.08 μmol/L)and uric indicant(72.6±13.1 mg/L vs92.7±18.5 mg/L)in the experimental group were significantly different fromthe control group(t=2.45～6.83,all P<0.05).The levels of TC(5.88±1.05 mmol/L vs 5.47±0.85 mmol/L),LDL-C(3.53±0.77 mmol/L vs 3.21±0.66 mmol/L),HCY(21.3±3.69 μmol/L vs 18.6±3.17 μmol/L)and uric indicant(86.3±18.9 mg/L vs 72.6±13.1 mg/L)in the experimental group were significantly different from those before the experiment(t=2.31～5.76,all P<0.05),and there was no significant difference in the levels of TG(1.38±0.73 mmol/L vs 1.33±0.44 mmol/L),HDL-C(1.75±0.37 mmol/L vs 1.63±0.29 mmol/L)before and after the experiment(t=1.22,1.09,P>0.05).Spearman correlation analysis showed that uric indicant levels were positively correlated with TC,LDL-C and HCY levels(r=0.582～0.624,all P<0.05).Conclusion Detection of uric indicant levels can effectively reduce blood lipid and homocysteine levels in middle-aged and elderly people,thereby reduce the risk of hypertension,arteriosclerosis and other cardiovascular diseases in middle-aged and elderly people.

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备注/Memo

备注/Memo:
作者简介:韩 振(1987-),男,本科,学士,主管检验师,主要从事生化检验与临床,E-mail:zz.19870125@163.com。
更新日期/Last Update: 2018-11-30