[1]曹清芸a,柏明见a,何美琳a,等.B族链球菌在妊娠末期孕妇中的感染状态与阴道微生态评分相关性分析[J].现代检验医学杂志,2019,34(02):122-124.[doi:10.3969/j.issn.1671-7414.2019.02.031]
　CAO Qing-yuna,BAI Ming-jiana,HE Mei-lina,et al.Correlation between Group B Streptococcal Infectionand Nugent Score at the Third Trimester of Pregnancy[J].Journal of Modern Laboratory Medicine,2019,34(02):122-124.[doi:10.3969/j.issn.1671-7414.2019.02.031]
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B族链球菌在妊娠末期孕妇中的感染状态与阴道微生态评分相关性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年02期
页码:
122-124
栏目:
检验与临床
出版日期:
2019-05-11

文章信息/Info

Title:
Correlation between Group B Streptococcal Infectionand Nugent Score at the Third Trimester of Pregnancy
文章编号:
1671-7414(2019)02-122-03
作者:
曹清芸a; 柏明见a; 何美琳a; 侯 芳b; 梁国威a
(航天中心医院a.检验科; b.病理科,北京 100049)
Author(s):
CAO Qing-yuna; BAI Ming-jiana; HE Mei-lina; HOU Fangb; LIANG Guo-weia
(a.Department of Clinical Laboratory; b.Department of Pathology,Aerospace Central Hospital,Beijing 100049,China)
关键词:
妊娠末期;  B族链球菌;  Nugent评分;  细菌性阴道炎
分类号:
R378.12; R711.73
DOI:
10.3969/j.issn.1671-7414.2019.02.031
文献标志码:
A
摘要:
目的 对妊娠末期B族链球菌(GBS)感染状况与阴道微生态Nugent评分进行相关性分析。方法 2017年10月～2018年8月共收集621例妊娠35～37周孕妇的生殖道分泌物标本,应用荧光定量PCR检测GBS,应用涂片革兰氏染色进行Nugent评分,以GBS结果阳性与否分组,比较两组间Nugent评分差异有无统计学意义,以Nugent评分分组比较组间GBS阳性率差异有无统计学意义,双侧P<0.05为差异有统计学意义。结果 GBS阴性组与阳性组间Nugent评分分别为4.07±1.11,4.66±1.49,差异有统计学意义(t=-3.380,P<0.001)。根据Nugent评分分为正常组(≤3分)、疑似组(4～6分)与细菌性阴道炎(BV)患者组(≥7分),三组GBS阳性率分别为9.14%,11.81%和33.33%。两两比较显示,正常组与疑似组间阳性率差异无统计学意义(χ2=0.916,P=0.339),正常组与BV组组间比较差异有统计学意义(χ2=19.665,P<0.001),疑似组与BV组组间比较差异有统计学意义(χ2=17.689,P<0.001)。结论 GBS感染与阴道微生态紊乱有一定的相关性,Nugent评分越高,GBS感染率越高,有一定的临床提示意义。
Abstract:
Objective To analyze the correlation between the status of group B Streptococcus(GBS)infection and Nugent score in the late pregnancy.Methods 621 pregnant women at 35～37 weeksof gestation were collected for GBS and Nugent score,and compared the Nugent score between the GBS positive and negative groups,subsequently.According to Nugent score,all participants were divided into three subgroups,and compared the GBSpositive rates among the three subgroups.Results The Nugent score between GBS negative positive group was 4.07±1.11 vs 4.66±1.49(t=-3.380,P<0.001),respectively.According to Nugent score,the positiverates of GBS were 9.14%,11.81% and 33.33% respectively.The GBS positive rate in bacterial vaginosis(BV)group was the highest among the three subgroups.Conclusion The infection of GBS is correlated with vaginal microecological disturbance.

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备注/Memo

备注/Memo:
作者简介:曹清芸(1965-),女,主管技师,主要从事分子检验工作,E-mail:caoqingyun721@126.com。 通讯作者:梁国威(1968-),男,主任医师,主要从事生化与分子诊断专业,E-mail:LGW721@163.com。
更新日期/Last Update: 2019-04-30