[1]唐琼华,何伟业,陈智林.血清淀粉样蛋白A 与降钙素原水平检测在儿童感染性疾病中的诊断价值[J].现代检验医学杂志,2020,35(02):68-71.[doi:10.3969/j.issn.1671-7414.2020.02.020]
 TANG Qiong-hua,HE Wei-ye,CHEN Zhi-lin.Diagnostic Value of Serum Amyloid A and Procalcitonin Level inChildren with Infectious Diseases[J].Journal of Modern Laboratory Medicine,2020,35(02):68-71.[doi:10.3969/j.issn.1671-7414.2020.02.020]
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血清淀粉样蛋白A 与降钙素原水平检测在儿童感染性疾病中的诊断价值()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年02期
页码:
68-71
栏目:
论 著
出版日期:
2020-05-24

文章信息/Info

Title:
Diagnostic Value of Serum Amyloid A and Procalcitonin Level inChildren with Infectious Diseases
文章编号:
1671-7414(2020)02-068-05
作者:
唐琼华何伟业陈智林
( 广州中医药大学第一附属医院检验科,广州 510405)
Author(s):
TANG Qiong-hua HE Wei-ye CHEN Zhi-lin
(Department of Clinical Laboratory, the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405, China)
关键词:
儿童感染性疾病淀粉样蛋白A降钙素原诊断价值
分类号:
R725;R446.11
DOI:
10.3969/j.issn.1671-7414.2020.02.020
文献标志码:
A
摘要:
目的 探讨血清淀粉样蛋白A(SAA)及降钙素原水平(PCT)在儿童感染性疾病中的诊断价值。方法 回顾性分析2019 年3~8 月于广州中医药大学第一附属医院就诊的150 例感染性疾病患儿的临床资料。其中,80 例细菌感染患儿纳入细菌感染组,70 例病毒感染患儿纳入病毒感染组,另随机选取50 例同期于该院体检健康儿童纳入对照组。采集三组血液样本,检测三组样本血清SAA 及PCT 水平,并分析其临床诊断价值。结果 三组血清SAA 及PCT 水平比较,差异均有统计学意义(F =17.383,11.169,均P ﹤ 0.05);细菌感染组和病毒感染组血清SAA 水平与对照组比较,差异均有统计学意义(t =13.795,10.247,均P ﹤ 0.05);细菌感染组血清PCT 水平与病毒感染组及对照组比较,差异均有统计学意义(t =15.005,18.146,均P ﹤ 0.05);三组血清SAA 及PCT 阳性率比较,差异均有统计学意义(χ2=9.706,26.092,均P<0.05)。细菌感染组和病毒感染组SAA 阳性率均高于对照组(χ2=8.273,6.318,均P< 0.05)。细菌感染组PCT 阳性率高于病毒感染组及对照组(χ2=14.268,19.042,均P 值﹤ 0.05)。由ROC 曲线图可知,细菌感染组SAA及PCT 曲线下面积分别为0.785 及0.824,病毒感染组SAA 及PCT 曲线下面积分别为0.813 及0.551。SAA 对病毒感染的诊断特异度较高,PCT 对细菌感染的诊断特异度较高,SAA 与PCT 联合诊断细菌感染的敏感度为92.18%,特异度为88.03%;SAA 与PCT 联合诊断病毒感染的敏感度为80.14%,特异度为86.52%。结论 SAA 诊断病毒感染的敏感度较高,PCT 诊断细菌感染的敏感度较高,SAA 与PCT 联合检测可有效诊断儿童感染性疾病。

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备注/Memo

备注/Memo:
作者简介:唐琼华(1978-),女,大学本科,主管技师,研究方向:临床检验体液方向,E-mail:teacher890@163.com。收稿日期:2019-12-16修回日期:2020-01-22
更新日期/Last Update: 2020-04-30