[1]周玉平a,朱传新a,龚娇芳b,等.新冠肺炎患者临床实验室检测结果分析[J].现代检验医学杂志,2020,35(02):83-87.[doi:10.3969/j.issn.1671-7414.2020.02.024]
 ZHOU Yu-pinga,ZHU Chuan-xina,GONG Jiao-fangb,et al.Analysis of Clinical Laboratory Test Results in Patients withNovel Coronavirus Pneumonia[J].Journal of Modern Laboratory Medicine,2020,35(02):83-87.[doi:10.3969/j.issn.1671-7414.2020.02.024]
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新冠肺炎患者临床实验室检测结果分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年02期
页码:
83-87
栏目:
新型冠状病毒肺炎检验专题
出版日期:
2020-05-24

文章信息/Info

Title:
Analysis of Clinical Laboratory Test Results in Patients withNovel Coronavirus Pneumonia
文章编号:
1671-7414(2020)02-083-05
作者:
周玉平a朱传新a龚娇芳b万禧伟c
(咸宁市第一人民医院a. 检验科;b. 呼吸内分泌科;c. 感染科 ,湖北咸宁 437000)
Author(s):
ZHOU Yu-pinga ZHU Chuan-xina GONG Jiao-fangb WAN Xi-weic
(a. Department of Clinical Laboratory;b. Department Respiratory and Endocrine ;c. Department of Infection,theFirst People’s Hospital of Xianning, Hubei Xianning 437000, China)
关键词:
新冠肺炎血细胞分析血细胞形态生化指标
分类号:
R373.19;R446.11
DOI:
10.3969/j.issn.1671-7414.2020.02.024
文献标志码:
A
摘要:
目的 探讨新冠肺炎(COVID-19)患者实验室检测结果的临床意义,为新冠肺炎诊治提供依据。方法 选取2020 年1 月26 日~ 2 月29 日收治的87 例COVID-19 患者(COVID-19 组)及100 例同期收治的有发热咳嗽症状但排除新冠肺炎的隔离观察者(对照组)的血细胞分析及CRP,ESR,ALT,AST,CK,CK-MB,Mb,PA,ALB,PCT,NT-pro BNP 和Cr 等生化指标和血气分析的检测结果。分析实验室检测结果在COVID-19 中的变化特征。结果 COVID-19 组Nst/Nsg 5.81±4.55,Mb 61.32±71.63 ng/ml,CK-MB 38.31±66.19 U/L,Nst (37.22±25.14)%,NLR3.57±2.61,CK 240.39±642.96 U/L,CRP 36.40±32.84 mg/L,异形淋巴细胞(0.91±0.49)%,ALT 47.24±32.09 U/L,AST 43.81±32.41 U/L,ESR 30.95±15.71mm/h,NEUT(77.00±12.00)%,LYMPH (1.15±0.41)×109/L,EOS(0.03±0.02)×109/L,PA 149.79±103.84 g/L,LYMPH(18.17±12.44)%,WBC(4.99±1.89)×109/L,NEUT(3.40±1.89)×109/L 和ALB 38.42±4.80g/L。与隔离观察组相比,COVID-19 组Nst/Nsg,Mb,CK-MB,Nst,NLR,CK,CRP,异形淋巴细胞,ALT,AST,ESR 和NEUT 水平较高, LYMPH,EOS,PA,LYMPH,WBC,NEUT 和ALB 水平较低,差异均有统计学意义(t=0.862~77.863,均P<0.05);与隔离观察组和普通型相比,重症与危重症COVID-19 患者PO2,Ca2+ 和SaO2 较低,随病情加重而降低;NT-pro BNP 和Cr 偏高,随病情加重而增高。随着病情的发展Nst/Nsg,Nst,异形淋巴细胞,WBC 和NEUT 逐渐升高, LYMPH,EOS 和PA 仍低于正常,甚至下降,炎症和损伤标志物随病情加重而增高,且急性期高于恢复期,与肺部疾病的严重程度正相关。结论 COVID-19 组的实验室检测结果分析显示出该病毒对肺、心、肝多器官功能有损害,实验室指标为循证医学、精准治疗该病提供可靠依据。

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备注/Memo

备注/Memo:
作者简介:周玉平(1975-),女,大学本科,副主任技师,研究方向:临床血液学检查和临床输血治疗等,E-mail:3275168458@qq.com。收稿日期:2020-03-13修回日期:2020-03-20
更新日期/Last Update: 2020-04-30