[1]吕亚玲.血清GLU 和尿液mALB 水平检测对白内障发生的预测价值评价[J].现代检验医学杂志,2020,35(04):154-157.[doi:10.3969/j.issn.1671-7414.2020.04.039]
 L? Ya-ling.Evaluation of Predictive Value of Serum GLU and Urine mALB Levels in Cataract Development[J].Journal of Modern Laboratory Medicine,2020,35(04):154-157.[doi:10.3969/j.issn.1671-7414.2020.04.039]
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血清GLU 和尿液mALB 水平检测对白内障发生的预测价值评价()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年04期
页码:
154-157
栏目:
检验与临床
出版日期:
2020-09-05

文章信息/Info

Title:
Evaluation of Predictive Value of Serum GLU and Urine mALB Levels in Cataract Development
文章编号:
1671-7414(2020)04-154-04
作者:
吕亚玲
(南京宁益眼科中心,南京 210000)
Author(s):
L? Ya-ling
(Ningyi Ophthalmic Center of Nanjing, Nanjing 210000, China)
关键词:
白内障尿微量清蛋白血葡萄糖Logistic 回归
分类号:
R776.1;R446
DOI:
10.3969/j.issn.1671-7414.2020.04.039
文献标志码:
A
摘要:
目的 采用Logistic 回归及受试者工作特征(ROC)曲线综合评价实验室常规检测项目对白内障发生的预测价值。方法 收集2018 年1~12 月于南京宁益眼科中心就诊的50 例白内障患者及同期50 例非白内障患者,检测分析实验室常规检测项目尿素(BUN)、肌酐(CREA)、总胆固醇(total cholesterol,TC)、三酰甘油(triglyceride ,TG)、血糖(GLU)、纤维蛋白原(fibrinogen, FIB)、活化部分凝血活酶时间(APTT)、超敏C 反应蛋白(hs-CRP)和尿微量清蛋白(mALB)的水平,对有统计学意义的指标, 先采用多因素Logistic 回归模型分析,再进行ROC 分析模型的预测价值。结果 ①白内障患者组GLU 及mALB 均高于非白内障组,差异具有统计学意义(t=3.68, P=0.000; t=2.06,P=0.042)。② Logistic回归分析,GLU (OR=2.532, 95% CI:1.224~5.237) 和 mALB (OR=1.155, 95% CI:1.070~1.247) 与白内障发生发展存在相关性(P<0.05)。据此构建的白内障发生的风险预测模型为Y=1/[1+e- (0.929X1+0.144X2-7.852) ]。③两者联合诊断白内障的ROC曲线下面积(AUC)大于GLU 和mALB 单项检测的AUC。结论 GLU 和mALB 与白内障疾病发生发展显著相关, 白内障风险预测模型有一定的预测价值。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2020-01-08修回日期:2020-04-15作者简介:吕亚玲(1973-),女,本科,主管技师,主要从事临床生物化学检验,E-mail:514729372@qq.com。
更新日期/Last Update: 2020-10-08