[1]张书婉,黄君华,吴文婧,等.外周血 NLR 与 PLR 对儿童完全型川崎病冠状动脉损伤的预测分析[J].现代检验医学杂志,2020,35(06):38-41.[doi:doi:10.3969/j.issn.1671-7414.2020.06.010]
 ZHANG Shu-wan,HUANG Jun-hua,WU Wen-jing,et al.Prediction Analysis of NLR and PLR for the Development of Coronary ArteryLesions in Patients with Complete Kawasaki Disease[J].Journal of Modern Laboratory Medicine,2020,35(06):38-41.[doi:doi:10.3969/j.issn.1671-7414.2020.06.010]
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外周血 NLR 与 PLR 对儿童完全型川崎病冠状动脉损伤的预测分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年06期
页码:
38-41
栏目:
论著
出版日期:
2020-12-30

文章信息/Info

Title:
Prediction Analysis of NLR and PLR for the Development of Coronary ArteryLesions in Patients with Complete Kawasaki Disease
文章编号:
1671-7414(2020)06-038-05
作者:
张书婉1 黄君华2 吴文婧3 祝撷英1 杨 立3 曹三成1
(1. 西安市儿童医院检验科,西安 710003;2. 西安医学院医学技术学院,西安 710021;3. 西安交通大学第一附属医院检验科,西安 710061)
Author(s):
ZHANG Shu-wan 1 HUANG Jun-hua 2 WU Wen-jing 3 ZHU Xie-ying 1 YANG Li 3 CAO San-cheng 1 .
(1.Department of Clinical Laboratory, Xi’an Children’s Hospital,Xi’an 710003, China; 2.Department of MedicalTechnology, Xi’an Medical University,Xi’an 710021, China; 3.Department of Clinical Laboratory, the First AffiliatedHospital of Xi’an Jiaotong Uni
关键词:
川崎病冠状动脉损伤中性粒细胞与淋巴细胞比值血小板与淋巴细胞比值
分类号:
R725.5;R446.11
DOI:
doi:10.3969/j.issn.1671-7414.2020.06.010
文献标志码:
A
摘要:
目的 探讨中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)预测完全型川崎病(CKD)患儿冠状动脉损伤(CAL)的价值。方法 回顾性分析 2018 年 1 月 1 日 ~12 月 31 日在西安市儿童医院和西安交通大学第一附属医院确诊为 CKD 的 185 例患儿的临床资料,其中发生 CAL 者 37 例,未发生 CAL 者 148 例;选取同时期93 例上呼吸道病毒感染儿童为发热对照组,60 例健康体检儿童为健康对照组。收集所有纳入对象的血细胞检测结果并进行统计学分析。结果 CKD 患儿中发生 CAL 者 NLR 和 PLR 均高于未发生 CAL 者,差异有统计学意义(χ 2 =3.69, 4.13,均P<0.01) ;NLR和PLR预测川崎病CAL的cut-off 值分别为4.13和126.82,敏感度和特异度分别为83.8%和76.1%(NLR)及81.1%和67.0%(PLR);NLR与PLR联合预测CAL的敏感度和特异度分别为86.5%和80.7%,ROC曲线下面积0.874。结论 CKD 急性期 NLR 与 PLR 对预测患儿是否发生 CAL 具有一定的价值。

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更新日期/Last Update: 2020-12-20