[1]杨 斌,李 华.2016~2019年陕西省榆林市细菌耐药监测网成员单位金黄色葡萄球菌的临床分布与耐药性变迁[J].现代检验医学杂志,2021,36(01):81-84.[doi:10.3969/j.issn.1671-7414.2021.01.021]
 YANG Bin,LI Hua.Clinical Distribution and Drug Resistance Changes of Staphylococcus Aureus, A Member of the Bacterial Resistance Monitoring Network in Yulin, Shaanxi Province from 2016 to 2019[J].Journal of Modern Laboratory Medicine,2021,36(01):81-84.[doi:10.3969/j.issn.1671-7414.2021.01.021]
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2016~2019年陕西省榆林市细菌耐药监测网成员单位金黄色葡萄球菌的临床分布与耐药性变迁()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年01期
页码:
81-84
栏目:
论 著
出版日期:
2021-02-05

文章信息/Info

Title:
Clinical Distribution and Drug Resistance Changes of Staphylococcus Aureus, A Member of the Bacterial Resistance Monitoring Network in Yulin, Shaanxi Province from 2016 to 2019
文章编号:
1671-7414(2021)01-081-04
作者:
杨 斌李 华
(陕西省府谷县人民医院,陕西府谷 719400)
Author(s):
YANG Bin LI Hua
(Fugu County People’s Hospital of Shaanxi, Shaanxi Fugu 719400,China)
关键词:
金黄色葡萄球菌临床分布耐药性
分类号:
R378.11;R446.5
DOI:
10.3969/j.issn.1671-7414.2021.01.021
文献标志码:
A
摘要:
目的 分析 2016-2019年陕西省榆林市细菌耐药监测网成员单位金黄色葡萄球菌临床分布与耐药性变迁,为金黄色葡萄球菌感染合理用药提供依据。方法 收集 2016~2019年陕西省榆林市细菌耐药监测网成员单位(榆林市一院、榆林市二院、府谷县人民医院、神木市医院、榆林星元医院、定边县医院、靖边县医院、绥德县医院共 8家医院)常规分离、培养的 1 296株金黄色葡萄球菌的监测数据,所有检测按 CLSI2019规定的标准执行。结果 1 296株金黄色葡萄球菌( SAU)从科室分布看,主要分布在外科( 19.3%)、儿科( 13.1%)、重症医学科( 8.7%)和骨科( 8.2%);从标本类型分布看,主要分布在痰液( 23.8%)、分泌物( 22.7%)、脓液( 13.7%)和伤口( 11.9%)。在 1 296株 SAU中甲氧西林耐药金黄色葡萄球菌( MRSA)占比为 20.2%;MRSA比甲氧西林敏感金黄色葡萄球菌( MSSA)抗生素耐药率明显偏高,两组之间的差异有统计学意义( P<0.01);四年内对青霉素耐药率都在 93.3%以上;对红霉素耐药率都在 62.7%以上;对克林霉素耐药率都在 26.8%以上;对复方新诺明耐药率都在 25%以下,且有连续下降的趋势;对氯霉素、利福平、环丙沙星、莫西沙星和庆大霉素的耐药性都在 15%以下;对利奈唑胺、万古霉素、替考拉宁和呋喃妥因四类药物尚未产生耐药性。结论 利奈唑胺、万古霉素、替考拉宁及呋喃妥因均可作为 SAU感染的经验用药,除此外其他抗生素选用建议要参照药敏试验进行,以此来促进金黄色葡萄球菌感染的精准治疗并延缓耐药菌株的出现。

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备注/Memo

备注/Memo:
作者简介:杨斌(1973-),男,研究生,主任技师,研究方向:细菌耐药, E-mail:654675619@qq.com。
通讯作者:李华(1973-),女,本科,副主任技师,研究方向:临床检验, E-mail:512954051@qq.com。
更新日期/Last Update: 2021-02-05