[1]杜春娟,李 丹,王 岑,等.急性心肌梗死并发阿斯综合征患者血清和肽素与 Adropin 水平联合检测的早期诊断价值研究[J].现代检验医学杂志,2021,36(03):97-99.[doi:10.3969/j.issn.1671-7414.2021.03.022]
 DU Chun-juan,WANG Cen,HUYAN-Li,et al.Study on the Early Diagnostic Value of Serum Copeptin and Adropin Levels in Patients with Acute Myocardial Infarction Complicated with Adams-stokes Syndrome[J].Journal of Modern Laboratory Medicine,2021,36(03):97-99.[doi:10.3969/j.issn.1671-7414.2021.03.022]
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急性心肌梗死并发阿斯综合征患者血清和肽素与 Adropin 水平联合检测的早期诊断价值研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年03期
页码:
97-99
栏目:
论 著
出版日期:
2021-05-31

文章信息/Info

Title:
Study on the Early Diagnostic Value of Serum Copeptin and Adropin Levels in Patients with Acute Myocardial Infarction Complicated with Adams-stokes Syndrome
文章编号:
1671-7414(2021)03-097-04
作者:
杜春娟李 丹王 岑
(1. 西安高新医院急诊科,西安 710075;2. 西安交通大学第一附属医院呼吸与危重症医学科,西安 710061)
Author(s):
DU Chun-juan1 WANG Cen1 HUYAN-Li1 LI Dan2 ZHANG Zhen1
(1.Department of Emergency, Xi’an Gaoxin Hospital, Xi’an 710075, China;2. Department of Respiratory and CriticalCare Medicine, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China)
关键词:
急性心肌梗死阿斯综合征血清和肽素Adropin
分类号:
R542.22;R392.11
DOI:
10.3969/j.issn.1671-7414.2021.03.022
文献标志码:
A
摘要:
目的 探究急性心肌梗死 (acute myocardial infarction, AMI) 并发阿斯综合征 (Adams-stokes syndrome) 患者血清和肽素与 Adropin 水平联合检测的早期诊断价值研究。方法 选取西安高新医院急诊科 2016 年 1 月 ~2020 年 1 月收治的 70 例 AMI 并发阿斯综合征患者为观察组,另随机选取同期 70 例健康体检者为对照组。应用酶联免疫吸附法 (ELISA)检测两组血清和肽素和 Adropin 的水平,绘制受试者 ROC(receiver operating characteristic) 工作曲线,评估血清和肽素,Adropin 和两者联合检测的诊断特性。结果 血清 Adropin ≥ 170.4 pg/ml 为 AMI 并发阿斯综合征的临界值。两组AMI 并发阿斯综合征发病后 0,2,4 和 6 h 时和肽素和血清中 Adropin 水平差异均具有统计学意义 (U=5.325~294.457,均 P < 0.05)。不同发病时间点和肽素联合 Adropin 的异常率均高于其单独检测。和肽素灵敏度为 91.02%,特异度为 74.51%。血清中 Adropin 灵敏度为 86.83%,特异度为 77.98%,将两者联合灵敏度提高至 92.71%,特异度提高至82.65%。结论 血清和肽素联合 Adropin 在 AMI 并发阿斯综合征发病初期具有较高的异常率,其灵敏度和特异度均高于两者单独检测,可用于 AMI 并发阿斯综合征的早期识别和诊断。

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备注/Memo

备注/Memo:
作者简介:杜春娟(1984-),女,本科,主治医师,研究方向:脑卒中,E-mail:1402336710@qq.com。
通讯作者:张珍(1987-),女,本科,主治医师,研究方向:脑卒中,E-mail:luckzhangzhen@163.com。
更新日期/Last Update: 1900-01-01