[1]李 敏,孙江漫,孟祥兆,等.北京地区老年人群血浆维生素A，D 和E 水平检测结果分析[J].现代检验医学杂志,2022,37(05):159-163.[doi:10.3969/j.issn.1671-7414.2022.05.031]
　LI Min,SUN Jiang-man,MENG Xiang-zhao,et al.Analysis of Plasma Vitamin A，D and E Levels in Beijing Elderly Population[J].Journal of Modern Laboratory Medicine,2022,37(05):159-163.[doi:10.3969/j.issn.1671-7414.2022.05.031]
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北京地区老年人群血浆维生素A，D 和E 水平检测结果分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第37卷
期数:
2022年05期
页码:
159-163
栏目:
研究简报·实验技术
出版日期:
2022-09-15

文章信息/Info

Title:
Analysis of Plasma Vitamin A，D and E Levels in Beijing Elderly Population
文章编号:
1671-7414（2022）05-159-05
作者:
李 敏; 孙江漫; 孟祥兆; 邵 燕; 韩玉霞; 于洪远
北京航天总医院检验科，北京 100076
Author(s):
LI Min;  SUN Jiang-man;  MENG Xiang-zhao;  SHAO Yan; HAN Yu-xia; YU Hong-yuan
Department of Clinical Laboratory，Beijing Aerospace General Hospital, Beijing 100076,China
关键词:
维生素A; D; E; 高效液相色谱串联质谱法
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2022.05.031
文献标志码:
A
摘要:
目的　对北京地区60 岁以上老年人群血浆维生素A，D 和E 水平检测结果进行分析，了解性别、年龄和季节对维生素水平的影响。方法　回顾分析2020 年12 月～ 2021 年11 月在北京航天总医院就诊的2 043 例60 岁以上老人的血浆维生素A，D 和E 水平, 按照性别、年龄和季节进行分组分析。结果　2 043 例老年人群血浆维生素A，D 和E水平分别为438.20（328.40, 563.00）ng/ml，13.70(9.70, 19.55) ng/ml 和8 311.40(6 430.50, 10 602.70) ng/ml，缺乏/ 不足率分别为19.43%，92.61% 和10.13%。不同性别的维生素A 和E 水平及缺乏/ 不足率比较差异均无统计学意义（Z =-1.37，-0.27；χ2=0.49，4.33, 均P ＞ 0.05），女性维生素D水平低于男性，缺乏率高于男性，差异均有统计学意义（Z=-6.72，χ2=4.38, 均P ＜ 0.05）。不同年龄组间的维生素A，D 水平及维生素A，D，E 的缺乏/ 不足率比较差异均有统计学意义（H =40.82,18.21；χ2= 35.20, 20.08, 23.39, 均P ＜ 0.05），70 岁以上老人维生素A 和D 水平随着年龄增长呈下降趋势，缺乏/ 不足率明显升高。不同季节的维生素A，D 和E 水平及缺乏/ 不足率比较差异具有统计学意义（H=75.50 ～ 225.87，χ2=21.41 ～ 70.94，均P ＜ 0.05）。秋季维生素A 水平最低，缺乏率最高。春季维生素E 水平最低，冬季缺乏率最高。冬季维生素D 水平最低，缺乏率最高。结论　北京地区老年人群血浆维生素A，D 和E 的缺乏/ 不足较普遍，尤其是维生素D，并且维生素水平与性别、年龄和季节有关。提倡老年人合理补充维生素，以满足机体需要。
Abstract:
Objective　To investigate the effects of age，sex and season on the levels of vitamin A，D and E in plasma of the elderly population over 60 years old in Beijing. Methods　Plasma levels of vitamin A，D and E in 2 043 patients over 60 years old who were admitted to Beijing Aerospace General Hospital from December 2020 to November 2021 were retrospectively analyzed and grouped according to age，sex and season. Results　The plasma levels of vitamin A，D and E in 2 043 elderly population were 438.20 (328.40,563.00) ng/ml，13.70(9.70,19.55) μg/ml and 8 311.40(6 430.50,10 602.70) ng/ml. The deficiency rates were 19.43%，92.61% and 10.13%, respectively. There were no significant differences in vitamin A and E levels and deficiency rate among different genders (Z =-1.37，-0.27；χ2=0.49，4.33, all P ＞ 0.05). The vitamin D level of female was lower than that of male and the deficiency rate was higher than that of male with statistical significance (Z=-6.72，χ2=4.38, all P ＜ 0.05). There were statistically significant differences in vitamin A and D levels and deficiency rates of vitamin A， D and E among different age groups （H =40.82,18.21；χ2= 35.20, 20.08, 23.39, all P ＜ 0.05）. Vitamin A and D levels of people over 70 years old showed a decreasing trend with the increase of age and the deficiency rate increased significantly. There were statistically significant differences in vitamin A， D and E levels and deficiency rate in different seasons （H =75.50 ～ 225.87， χ2=21.41 ～ 70.94，all P ＜ 0.05）. The lowest vitamin A level and the highest deficiency rate were found in autumn. The vitamin E levels were the lowest in spring and deficiency rates were highest in winter. Vitamin D levels were lowest in winter and deficiency rates were highest. Conclusion　The deficiency of plasma vitamin A，D and E was common among the elderly in Beijing Area, especially vitamin D. Vitamin levels were related to gender，age and season.The elderly should be encouraged to supplement vitamins reasonably to meet the needs of the body.

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备注/Memo

备注/Memo:
作者简介：李敏（1991-），女，本科，检验技师，主要从事临床化学标准化研究，E-mail:1140368364@qq.com。
通讯作者：于洪远，副主任检验技师，E-mail:jyk711@sina.com。
更新日期/Last Update: 2022-09-15