[1]王 鑫,张 瑞,李雅静,等.白藜芦醇对葡萄球菌标准株抑菌作用研究[J].现代检验医学杂志,2015,30(02):91-93.[doi:10.3969/j.issn.1671-7414.2015.02.028]
 WANG Xin,ZHANG Rui,LI Ya-jing,et al.Antibacterial Effect of Resveratrol on Staphylococcus Aureus Standard Strains[J].Journal of Modern Laboratory Medicine,2015,30(02):91-93.[doi:10.3969/j.issn.1671-7414.2015.02.028]
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白藜芦醇对葡萄球菌标准株抑菌作用研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年02期
页码:
91-93
栏目:
研究简报·实验技术
出版日期:
2015-03-20

文章信息/Info

Title:
Antibacterial Effect of Resveratrol on Staphylococcus Aureus Standard Strains
作者:
王 鑫1张 瑞1李雅静1吴淑惠2
1.河北医科大学第二医院检验科,石家庄 050000; 2.河北医科大学基础课教学部病原与免疫教研室,石家庄 050012
Author(s):
WANG Xin1ZHANG Rui1LI Ya-jing1WU Shu-hui2
1.Department of Clinical Laboratory,the Second Hospital of Hebei Medical University, Shijiazhuang 050000,China; 2.Pathogen and Immune Teaching and Research Section of Basic Conrse Education,Hebei Medical University,Shijiazhuang 050012,China
关键词:
白藜芦醇 最低抑菌浓度 生长曲线 抑制作用
分类号:
R378.11; R446.5
DOI:
10.3969/j.issn.1671-7414.2015.02.028
文献标志码:
A
摘要:
目的 探讨白藜芦醇(resveratrol,简称RES)对金黄色葡萄球菌抑菌作用。方法 以金黄色葡萄球菌标准株ATCC 25923(金葡菌标准株)作为研究主体检测RES对其的最低抑菌浓度(MIC),绘制不同浓度RES作用下金黄色葡萄球菌的生长曲线。结果 RES对金黄色葡萄球菌标准株MIC为0.256 mg/ml; 在RES浓度为1/4 MIC和1/2 MIC时,生长明显受抑,生长曲线不典型,对数生长期比正常对照组减缓; RES浓度为1MIC和2MIC时金黄色葡萄球菌完全受抑制,生长曲线完全失去正常生长状态,趋于平缓。结论 RES对金黄色葡萄球菌标准株抑制作用明显。
Abstract:
Objective To evaluate the antibacterial activity of Resveratrol(RES)against Staphylococcus aureus standard strains.Methods Minimal inhibitory concentrations was tested.Growth curve of RES were used to study.Results The MIC of Staphylococus were 0.256 mg/ml.RES inhibit growth of Staphylococal referenceculture.Conclusion RES had strong antibacterial activity agains Staphylococal reference culture.

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备注/Memo

备注/Memo:
基金项目:河北省重点科技研究计划项目,课题号:20100076。 作者简介:王 鑫(1970-),女,学士,研究方向:病原微生物和分子生物学,E-mail:wx16136@163.com。 通讯作者:吴淑慧(1967-),女,硕导,研究方向:分子微生物学,E-mail:hbwushui@126.com。
更新日期/Last Update: 2015-03-20