[1]侯 欣a,张 丽a,徐英春a,等.念珠菌耐药机制研究进展[J].现代检验医学杂志,2016,31(01):60-64.[doi:10.3969/j.issn.1671-7414.2016.01.017]
 HOU Xina,ZHANG Lia,XU Ying-chuna,et al.Research Review on Antifungal Drug Resistance Mechanisms in Candida Spp[J].Journal of Modern Laboratory Medicine,2016,31(01):60-64.[doi:10.3969/j.issn.1671-7414.2016.01.017]
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念珠菌耐药机制研究进展()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年01期
页码:
60-64
栏目:
综述
出版日期:
2016-01-25

文章信息/Info

Title:
Research Review on Antifungal Drug Resistance Mechanisms in Candida Spp
作者:
侯 欣a张 丽a徐英春a赵玉沛b
中国医学科学院北京协和医院 a.检验科; b.基本外科,北京 100730
Author(s):
HOU XinaZHANG LiaXU Ying-chunaZHAO Yu-peib
a.Department of Clinical Laboratory; b.Department of General Surgery,Peking Union Medical College Hospital Chinese Academy of Medical Sciences,Beijing 100730,China
关键词:
念珠菌 抗真菌药物耐药 药敏试验 耐药基因
分类号:
R379.4; R446
DOI:
10.3969/j.issn.1671-7414.2016.01.017
文献标志码:
A
摘要:
近年来念珠菌感染的流行病学发生改变,尽管白念珠菌仍是大多数医院引起侵袭性念珠菌病的主要病原体,但是非白念珠菌的感染比例有所增加。不同种念珠菌对不同药物的敏感性不同,耐药现象成为念珠菌感染治疗的主要问题,抗菌药物常导致临床念珠菌感染治疗失败。了解念珠菌耐药机制对提高患者预后和加强感染控制十分重要。该文对念珠菌的耐药机制做一综述。
Abstract:
In recent years,the epidemiology of Candidainfection has changed.Although Candida albicans is still the main pathogens causing invasive candidiasis,non-albicans Candida species are increasingly encountered.Different Candida species show distinct sensitivity of different drugs.The emergence of drug resistance has become the main problem of Candida infection treatment.Antifungal resistance of clinical Candida infections often lead to treatment failure.The review of resistance mechanisms and theeffect on clinical treatment is very significant to improve the prognosis of patients and strengthen the control of infection.This text reviews the present state of the detection of mechanisms of resistance in Candida spp.

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备注/Memo

备注/Memo:
基金项目:卫生公益性行业科研专项(项目编号:201402001)。 作者简介:侯 欣(1990-),女,博士研究生,主要从事微生物鉴定及耐药机制研究。 通讯作者:徐英春,研究员,E-mail:xycpumch@139.com
更新日期/Last Update: 2016-01-20