[1]章晓燕,王 薇,王治国.临床检验正确度控制品-评估偏倚[J].现代检验医学杂志,2016,31(05):147-149.[doi:10.3969/j.issn.1671-7414.2016.05.044]
　ZHANG Xiao-yan,WANG Wei,WANG Zhi-guo.Trueness Controls of Clinical Laboratory to Assess Bias[J].Journal of Modern Laboratory Medicine,2016,31(05):147-149.[doi:10.3969/j.issn.1671-7414.2016.05.044]
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临床检验正确度控制品-评估偏倚()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年05期
页码:
147-149
栏目:
质量控制·实验室管理
出版日期:
2016-10-21

文章信息/Info

Title:
Trueness Controls of Clinical Laboratory to Assess Bias
文章编号:
1671-7414(2016)05-147-03
作者:
章晓燕; 王 薇; 王治国
北京医院 国家老年医学中心卫生部临床检验中心,北京 100730
Author(s):
ZHANG Xiao-yan; WANG Wei; WANG Zhi-guo
National Center for Clinical Laboratories of the Ministry of Health,Beijing Hospital,Beijing 100730,China
关键词:
正确度控制品;  偏倚;  统计质量控制;  系统误差
分类号:
R446
DOI:
10.3969/j.issn.1671-7414.2016.05.044
文献标志码:
A
摘要:
精密度控制监测分析随机误差; 准确度控制评估总误差,包括随机误差和系统误差; 而正确度(偏倚)评估的是系统误差。正确度控制品应具有计量学溯源性,最好通过使用参考物质或参考方法来确定靶值,如果没有溯源至参考测量系统,来自不同实验室的同一患者检测结果的可比性可能是不理想的。正确度控制品还应具有互换性,即控制品与患者标本一样,在不同测量程序上的结果具有一致性,可以显示相同的数值关系。同时正确度控制品定值更适合设置在医学决定水平(MDLs)或其他有临床意义的浓度上,由参考物质的提供者制备并以与校准品相同的方式进行生产。
Abstract:
Precision controls monitor assay random error(reproducibility),accuracy controls assess total error,both random error and systematic error,and trueness(bias)of an assay represents systematic error.A trueness control should be metrological traceable,ideally with a target value determined by use of a reference material or a reference method,without metrological traceable to a reference measurement system,patient test results for the same patient from different laboratories may not be comparable.A trueness controlshould be commutable and its analytical response to a reference method and a routine field method should be equivalent to that of a patient sample.And truenesscontrol values should generally be set at medical decision levels and be prepared by the providers of reference materials and manufactured in the same fashionas a calibrator.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介:章晓燕(1992-),女,硕士研究生,研究方向:实验室质量管理,E-mail:553434613@qq.com。
通讯作者:王治国,研究员,E-mail:zgwang@nccl.org.cn。
更新日期/Last Update: 2016-10-30