参考文献/References:
[1] Javed F, Manzoor S, Khattak AA,et al.Molecular characterization and fluorescence analysis of HCV non-structural proteins NS3,NS3-4A and NS4A of genotype 3a[J].Acta Virol,2015,59(3):284-294.
[2] Mohd Hanafiah K, Groeger J, Flaxman AD,et al.Global epidemiology of hepatitis C virus infection:new estimates of age-specific antibody to HCV seroprevalence[J].Hepatology,2013,57(4):1333-1342.
[3] Aman W,Mousa S,Shiha G,et al.Current status and future directions inthe management of chronic hepatitis C[J].Virology Journal,2012(9):57.
[4] Lavanchy D.The global burden of hepatitis C[J].Liver Int,2009,29(Suppl1):74-81.
[5] Chen Y,Verfaillie CM.MicroRNAs:the fine modulators of liver development and function[J].Liver Int,2014,34(7):976-990.
[6] Friedman RC,Farh KK,Burge CB,et al.Most mammalian mRNAs are conservedtargets of microRNAs[J].Genome Res,2009,19(1):92-105.
[7] Tsang JS,Ebert MS,van Oudenaarden A.Genome-wide dissection of microRN-A functions and cotargeting networks using gene set signatures[J].Mol Cell,2010,38(1):140-153.
[8] Gao FB.Context-dependent functions of specific microRN-As in neuronaldevelopment[J].Neural Dev,2010(5):25.
[9] Yang B,Lin H,Xiao J,et al.The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2[J].Nat Med,2007,13(4):486-491.
[10] Small EM,Olson EN.Pervasive roles of microRNA-s in cardiovascular biology[J].Nature,2011,469(7330):336-342.
[11] O'Connell RM,Chaudhuri AA,Rao DS,et al.Inositol phosphatase SHIP1 is a primary target of miR-155[J].Proc Natl Acad Sci USA,2009,106(17):7113-7118.
[12] O'Connell RM,Rao DS,Chaudhuri AA,et al.Physiological and pathological roles for microRNAs in the immune system[J].Nat Rev Immunol,2010,10(2):111-122.
[13] Chiche J,Pommier S,Beneteau M,et al.GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependentinduction of HIF-1α[J].Leukemia,2015,29(5):1163-1176.
[14] Bandiera S,Hatem E,Lyonnet S,et al.MicroRNAs in diseases:from candidate to modifier genes[J].Clin Genet,2010,77(4):306-313.
[15] Hrdlickova B,de Almeida RC,Borek Z,et al.Genetic variation in the non-coding genome:involvement of micro-RNAs and long non-coding RNAs in disease[J].Biochim Biophys Acta,2014,1842(10):1910-1922.
[16] McManus DD,Freedman JE.MicroRNAs in platelet function and cardiovascular disease[J].Nat Rev Cardiol,2015,12(12):711-717.
[17] Feiersinger F, Nolte E, Wach S,et al.MiRNA-21 expression decreasesfrom primary tumors to liver metastases in colorectal carcinoma[J].PLoS One,2016,11(2):e0148580.
[18] Dong H,Lei J,Ding L,et al.MicroRNA:function,detection,and bioanalysis[J].Chem Rev,2013,113(8):6207-6233.
[19] Gupta P,Cairns MJ,Saksena NK.Regulation of ge-ne expression by microRNA in HCV infection and HCV-mediated hepatocellular carcinoma[J].Imperial College London,2014,11(4):1-14.
[20] Luna JM,Scheel TK,Danino T,et al.Hepatitis C virus RNA functionallysequesters miR-122[J].Cell,2015,160(6):1099-1110.
[21] Jopling CL,Yi M,Lancaster AM,et al.Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA[J].Science(New York,N.Y),2005,309(5740):1577-1581.
[22] Li Y,Masaki T,Shimakami T,et al.hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication[J].J Virol,2014,88(13):7199-7209.
[23] Janssen HL, Reesink HW, Lawitz EJ,et al.Treatment of HCV infection by targeting microRNA[J].N Engl J Med,2013,368(18):1685-1694.
[24] 晋 云,江 行,卿德科,等.MiR-122在肝细胞癌中的表达及其与肿瘤表型标志物的相关性研究[J].中华临床医师杂志(电子版),2013,7(24):11259-11262.
Jin Y,Jiang X,Qing DK,et al.Study of correlation between the expression of mir-122 and phenotype marker[J].Chin J Clinicians(Electronic Edition),2013,24(11):11259-11262.
[25] Tsai WC,Hsu PW,Lai TC,et al.MicroRNA-122,a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma[J].Hepatology,2009,49(5):1571-1582.
[26] Nakao K,Miyaaki H,Ichikawa T.Antitumor function of microRNA-122 against hepatocellular carcinoma[J].J Gastroenterol,2014,49(4):589-593.
[27] Hsu SH,Wang B,Kota J,et al.Essential metabolic,anti-inflammatory,and anti-tumorigenic functions of miR-122 in liver[J].J Clin Invest,2012,122(8):2871-2883.
[28] Li J,Ghazwani M,Zhang Y,et al.MiR-122 regulates collagen productionvia targeting hepatic stellate cells and suppressing P4HA1 expression[J].J Hepatol,2013,58(3):522-528.
[29] Spaniel C,Honda M,Selitsky SR,et al.MicroRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection[J].PLoS One,2013,8(10):e76867.