[1]鲁作华,刘倩倩,赵晓静,等.尿干化学分析法、散射比浊法、酶法检测尿清蛋白与尿肌酐及比值结果的一致性分析[J].现代检验医学杂志,2018,33(02):111-113,117.[doi:10.3969/j.issn.1671-7414.2018.02.001]
　LU Zuo-hua,LIU Qian-qian,ZHAO Xiao-jing,et al.Consistency Analysis of Urine Albumin Results by Urinary Dry Chemical Analysis,Scatter Turbidimetry,Enzymatic Assays and Urine Creatinine and Albumin-to-Creatinine Ratio[J].Journal of Modern Laboratory Medicine,2018,33(02):111-113,117.[doi:10.3969/j.issn.1671-7414.2018.02.001]
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尿干化学分析法、散射比浊法、酶法检测尿清蛋白与尿肌酐及比值结果的一致性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年02期
页码:
111-113,117
栏目:
研究简报·实验技术
出版日期:
2018-04-05

文章信息/Info

Title:
Consistency Analysis of Urine Albumin Results by Urinary Dry Chemical Analysis,Scatter Turbidimetry,Enzymatic Assays and Urine Creatinine and Albumin-to-Creatinine Ratio
文章编号:
1671-7414(2018)02-111-04
作者:
鲁作华; 刘倩倩; 赵晓静; 陈聚盛; 孙 力; 刘兴晖
上海市浦东新区公利医院检验科,上海 200135
Author(s):
LU Zuo-hua; LIU Qian-qian; ZHAO Xiao-jing; CHEN Ju-sheng; SUN Li; LIU Xing-hui
Department of Clinical Laboratory,Gongli Hospital of Pudong New Area,Shanghai 200135,China
关键词:
尿干化学分析;  尿清蛋白;  尿肌酐;  尿清蛋白肌酐比
分类号:
R446.1
DOI:
10.3969/j.issn.1671-7414.2018.02.001
文献标志码:
A
摘要:
目的 评价使用尿干化学法和散射比浊法检测尿清蛋白(Alb)、使用尿干化学法和酶法检测尿肌酐(Cr)及尿清蛋白肌酐比(ACR)的结果一致性分析。方法 收集157例清晨第一次尿液样本,尿清蛋白使用尿干化学法和散射比浊法、尿肌酐使用尿干化学法和酶法分别进行测定。采用kappa检验评价结果的一致性。结果 尿清蛋白kappa值为0.837 9(95%可信区间:0.718 1～0.957 7); 尿肌酐kappa值为0.769 7(95%可信区间:0.665 2～0.874 2); 尿清蛋白肌酐比kappa值为0.756 6(95%可信区间:0.628 6～0.884 6)。结论 尿干化学法检测尿清蛋白,尿肌酐及ACR的结果和散射比浊法检测尿Alb,酶法检测尿Cr及ACR结果具有较高的一致性。可以用于早期肾脏疾病的筛查以及CKD的分级中,初筛患者或长期病情维持过程中复查的监控手段。
Abstract:
Abstract:Objective To analysis of consistency of resultsinevaluating urine dry chemical method and nephelometry in the detection of urinealbumin(UAlb)and urine dry chemical method and enzymatic method in the detection of urinary creatinine(Cr)and albumin-to-creatinine ratio(ACR).Methods In 157 urine samples collected firstly in the morning,urine microalbumin was determined by the urine dry chemistry method and nephelometry,and urine creatinine was determined by the urine dry chemistry method and the enzyme method respectively.The kappa was applied to evaluating the consistency.Results The results of UAlb showed that the kappa was0.837 9(95%CI:0.718 1～0.957 7),the results of urine creatinine showed that the kappa was 0.769 7(95%CI:0.665 2～0.874 2),and the results of albumin-to-creatinine ratio showed that the kappa was 0.756 6(95%CI:0.628 6～0.8846).Conclusion The results of urine Alb,urinary creatinine and ACR by urine dry chemistry method and urine albumin by nephelometry,andurine Cr by enzymatic method and ACR had high consistency.Urine dry chemicalmethod can be used for screening of early renal disease and for screening in CKDgrading,screening for early screening or for long-term maintenance.

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备注/Memo

备注/Memo:
基金项目:浦东新区卫生系统重点学科群建设资助(PWZxq2017-15)。 作者简介:鲁作华(1978-),男,本科,主管技师,主要从事血液体液临床检验及血液细胞的临床及基础研究,E-mail:zuohualu@sina.com。 通讯作者:刘兴晖,男,主任技师,E-mail:syliuxh@163.com。
更新日期/Last Update: 2018-04-16