[1]林小平,刘晓良,余 瑶,等.支原体肺炎儿童与健康儿童血清拉曼光谱检测的差异性研究[J].现代检验医学杂志,2019,34(03):115-117,120.[doi:10.3969/j.issn.1671-7414.2019.03.028]
　LIN Xiao-ping,LIU Xiao-liang,YU Yao,et al.Study on the Difference of Serum Detection Technology of MycoplasmaPneumoniae Pneumonia(MPP)Based on Raman Spectroscopy in Children[J].Journal of Modern Laboratory Medicine,2019,34(03):115-117,120.[doi:10.3969/j.issn.1671-7414.2019.03.028]
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支原体肺炎儿童与健康儿童血清拉曼光谱检测的差异性研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年03期
页码:
115-117,120
栏目:
研究简报·实验技术
出版日期:
2019-06-20

文章信息/Info

Title:
Study on the Difference of Serum Detection Technology of MycoplasmaPneumoniae Pneumonia(MPP)Based on Raman Spectroscopy in Children
文章编号:
1671-7414(2019)03-115-04
作者:
林小平; 刘晓良; 余 瑶; 赵 芳; 苏艳丽
(商洛市中心医院检验科,陕西商洛 726000)
Author(s):
LIN Xiao-ping; LIU Xiao-liang; YU Yao; ZHAO Fang; SUYan-li
(Department of Clinical Laboratory,Shangluo Central Hospital,Shaanxi Shangluo 726000,China)
关键词:
光谱分析;  拉曼;  支原体肺炎;  早期诊断
分类号:
R563.15; Q503
DOI:
10.3969/j.issn.1671-7414.2019.03.028
文献标志码:
A
摘要:
目的 探讨血清拉曼光谱检测技术在支原体肺炎儿童与健康儿童的差异性。方法 收集商洛市中心医院2017年4～12月收治的支原体肺炎患儿血清100例作为实验组,选取同期健康儿童的血清100例作为对照组,使用全自动显微拉曼系统检测两组血清的拉曼光谱信号,对差异性进行分析。结果 与对照组相比,实验组血清在位移1 653.34 cm-1处拉曼光谱峰发生了减弱,差异有统计学意义(t=2.137,P<0.05),在位移1 152.93和1 515.33 cm-1处拉曼光谱峰得到了增强,差异有统计学意义(t=2.027和2.028,均P<0.05)。结论 初步研究表明支原体肺炎儿童与健康儿童血清拉曼光谱信号存在差异。
Abstract:
Objective To investigate the difference of serum Raman spectroscopy in children with Mycoplasma pneumoniae pneumonia(MPP)and healthy children.Methods The serum in 100 cases of children with MPP from April to December 2017 in the Shangluo Central Hospital were selected as experimental group,and 100 cases of healthy children's serum were selected as the control group.The Raman spectral signals from two groups of serum were detected using a fully automated micro Raman system,and the data wasanalyzed.Results Compared with control group,the experimental group children showed lower levels of the intensities at 1 653.34 cm-1(t=2.137,P<0.05),respectively,but higher levels of the intensitiesat 1 152.93 and 1 515.33 cm-1(t=2.027,2.028,all P<0.05).Conclusion This preliminary studies demonstrated that there was a difference in serum Raman spectral signals between children with MPP and healthy children.

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备注/Memo

备注/Memo:
作者简介:林小平(1987-),男,硕士,初级检验师,主要从事生化、微生物学检验,E-mail:lxpo7@outlook.com。 通讯作者:刘晓良(1971-),男,主任检验师,E-mail:shangluolxl@163.com。 收稿日期:2018-12-04 修回日期:2019-03-24
更新日期/Last Update: 2019-06-20