[1]张 晨a,朱海平a,金凤玲b,等.两株对万古霉素敏感性减低金黄色葡萄球菌的透射电镜下超微结构观察[J].现代检验医学杂志,2020,35(04):109-112.[doi:10.3969/j.issn.1671-7414.2020.04.027]
 ZHANG Chena,ZHU Hai-pinga,JIN Feng-lingb,et al.Study on Ultrastructure of VISA and Hetero-VISA Strains[J].Journal of Modern Laboratory Medicine,2020,35(04):109-112.[doi:10.3969/j.issn.1671-7414.2020.04.027]
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两株对万古霉素敏感性减低金黄色葡萄球菌的透射电镜下超微结构观察()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年04期
页码:
109-112
栏目:
研究简报 实验技术
出版日期:
2020-09-05

文章信息/Info

Title:
Study on Ultrastructure of VISA and Hetero-VISA Strains
文章编号:
1671-7414(2020)04-109-04
作者:
张 晨a朱海平a金凤玲b孙虹佳a姚立琼a
(兰州大学第一医院a. 检验科;b. 感染管理科, 兰州 730000)
Author(s):
ZHANG ChenaZHU Hai-pingaJIN Feng-lingbSUN Hong-jiaaYAO Li-qionga
(a.Department of Clinical Laboratory;b.Department of Infection Control, the First Hospital of Lanzhou University,Lanzhou 730000,China)
关键词:
万古霉素耐药万古霉素中介金黄色葡萄球菌异质性耐万古霉素金黄色葡萄球菌超微结构
分类号:
R378.11
DOI:
10.3969/j.issn.1671-7414.2020.04.027
文献标志码:
A
摘要:
目的 对前期课题筛选出的万古霉素中介金黄色葡萄球菌(vancomycin intermediate Stapylococcus aureus,VISA)及异质性耐万古霉素金黄色葡萄球菌(heterogeneous vancomycin resistant Stapylococcus aureus,hetero-VISA)进行透射电镜下的超微结构观察。方法 用KB法、琼脂稀释法和E-test 法、菌谱分析法对分离出的VISA 和h-VISA 进行确认,并用透射电镜法对其进行超微结构观察。结果 检测到的VISA 和h-VISA 经透射电镜观察发现菌株较标准菌株细胞壁增厚,细胞表面粗糙。结论 VISA 和h-VISA 等万古霉素敏感性减低金黄色葡萄球菌对万古霉素耐药很可能是由于细菌细胞壁增厚所引起的。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2020-03-21 修回日期:2020-05-13基金项目:甘肃省科技支撑计划项目( 项目编号:1011FKCA086)。作者简介:张晨(1984-),女,硕士研究生,主管检验师,研究方向为临床微生物检验,E-mail:happyjocelyn@163.com。通讯作者:朱海平,E-mail:13919178960@163.com。
更新日期/Last Update: 2020-10-08