[1]钟社兰,李功娟,樊阳阳,等.多囊卵巢综合征患者血清中Neudesin水平及其与多项生理生化指标的相关性分析[J].现代检验医学杂志,2021,36(02):98-100.[doi:doi:10.3969/j.issn.1671-7414.2021.02.023]
 ZHONG She-lan,LI Gong-juan,FAN Yang-yang,et al.Correlation Analysis of Serum Neudesin Level and Multiple Physiological and Biochemical Indexes in Patients with Polycystic Ovarian Syndrome[J].Journal of Modern Laboratory Medicine,2021,36(02):98-100.[doi:doi:10.3969/j.issn.1671-7414.2021.02.023]
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多囊卵巢综合征患者血清中Neudesin水平及其与多项生理生化指标的相关性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年02期
页码:
98-100
栏目:
论 著
出版日期:
2021-04-30

文章信息/Info

Title:
Correlation Analysis of Serum Neudesin Level and Multiple Physiological and Biochemical Indexes in Patients with Polycystic Ovarian Syndrome
文章编号:
1671-7414(2021)02-098-04
作者:
钟社兰李功娟樊阳阳
(1.安康市人民医院妇产科, 陕西安康 725000;2. 安康市汉滨区第一人民医院妇科,陕西安康 725000;3.陕西省人民医院产科,西安710068)
Author(s):
ZHONG She-lan LI Gong-juan FAN Yang-yang et al
(1.Department of Obstetrics and Gynecology, Ankang People’s Hospital, Shaanxi Ankang 725000, China;2. Department of Gynecology, the First People’s Hospital of Ankang Hanbin District, Shaanxi Ankang 725000, China;3.Department of Obstetrics, Shaanxi Provincial People’s Hospital, Xi’an 710068, China)
关键词:
多囊卵巢综合征生理指标生化指标身体质量指数
分类号:
R711.75;R446.11
DOI:
doi:10.3969/j.issn.1671-7414.2021.02.023
文献标志码:
A
摘要:
目的 探究多囊卵巢综合征(polycystic ovarian syndrome, PCOS)患者血清中Neudesin的水平及其与多项生理生化指标的相关性分析。方法 选取2018年9月至2019年10月安康市人民医院收治的53例PCOS患者为观察组,另选取同期50例体检健康女性为对照组。通过酶联免疫吸附测定法(ELISA)检测血清中Neudesin水平,电化学发光免疫分析法(ECLIA)检测血清卵泡刺激素(follicle-stimulating hormone, FSH)水平。结果 两组超敏C反应蛋白(high-sensitivity C-reactive protein, hs-CRP)和Neudesin水平比较差异具有统计学意义(t=11.63,12.69,均P<0.001),并且观察组的hs-CRP水平高于对照组(1.33±0.42mg/L vs 0.50±0.21mg/L),而观察组的Neudesin水平低于对照组(4.13±1.65ng/ml vs 6.83±2.19ng/ml)。Spearson相关性检验显示Neudesin与平均年龄、空腹血糖(fasting blood-glucose, FBG)、总胆固醇(total cholesterol, TC)、低密度脂蛋白胆固醇(low density lipoprotein cholesterin, LDL-C)、hs-CRP和FSH无显著相关性,而与身体质量指数(body mass index, BMI)呈显著负相关关系(r=-0.24,P=0.01)。结论 PCOS患者血清中Neudesin水平较低并且其受BMI的影响。

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备注/Memo

备注/Memo:
作者简介:钟社兰(1986-),女,本科,主治医师,研究方向:妇科内分泌,E-mail:ankangzhongshel@163.com。
通讯作者:王许锐(1989-),女,本科,住院医师,研究方向:妇科内分泌,E-mail:821487317@qq.com。
更新日期/Last Update: 2021-04-10