[1]王 媛,李文生.淋巴组织增生性疾病患者外周血EBV DNA定量检测临床意义的研究进展[J].现代检验医学杂志,2021,36(02):155-160.[doi:doi:10.3969/j.issn.1671-7414.2021.02.037]
 WANG Yuan,LI Wen-sheng.Advances in the Clinical Significance of Quantitative Detection of EBV DNA in Peripheral Blood of Patients with Lymphoproliferative Diseases[J].Journal of Modern Laboratory Medicine,2021,36(02):155-160.[doi:doi:10.3969/j.issn.1671-7414.2021.02.037]
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淋巴组织增生性疾病患者外周血EBV DNA定量检测临床意义的研究进展()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年02期
页码:
155-160
栏目:
综 述
出版日期:
2021-04-30

文章信息/Info

Title:
Advances in the Clinical Significance of Quantitative Detection of EBV DNA in Peripheral Blood of Patients with Lymphoproliferative Diseases
文章编号:
1671-7414(2021)02-155-07
作者:
王 媛李文生
(1. 西安医学院,西安 710068;2. 陕西省人民医院病理科,西安 710068)
Author(s):
WANG Yuan LI Wen-sheng
(1. Xi’an Medical University, Xi’an 710068, China; 2. Department of Pathology, Shaanxi Provincial People’s Hospital, Xi’an 710068, China)
关键词:
爱泼斯坦巴尔病毒淋巴组织增生性疾病定量聚合酶链反应
分类号:
R733;R446
DOI:
doi:10.3969/j.issn.1671-7414.2021.02.037
文献标志码:
A
摘要:
目前发现爱泼斯坦巴尔病毒(Epstein-Barr virus,EBV)与多种淋巴组织增生性疾病的关系越来越密切,主要包括EBV相关淋巴瘤、EBV阳性淋巴组织增殖性疾病(EBV+LPD)以及传染性单核细胞增多症(infectious mononucleosis, IM)等,以往研究认为EBV+LPD及IM的外周血EBV DNA有高拷贝数,而EBV相关淋巴瘤的外周血EBV DNA拷贝数一般不高,而近几年有不少文献报道EBV相关淋巴瘤外周血EBV DNA也出现高拷贝数,同时一些研究已经证实EBV DNA载量的检测不仅可以用于EBV相关淋巴组织增生性疾病的诊断,还可用于评价患者对治疗的反应及预后。该文主要对各种不同类型淋巴组织增生性疾病患者外周血EBV DNA定量检测做一综述,并探讨在治疗反应、预后判断中的价值和意义。

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备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目 (2019SF-089)。
作者简介:王媛(1994-),女,研究生,研究方向:EBV相关淋巴瘤,E-mail:1357752993@qq.com。
通讯作者:李文生(1968-),男,医学博士,主任医师,研究方向:肿瘤病理诊断及淋巴瘤病理研究,E-mail: liwensheng263@sohu.com 。
更新日期/Last Update: 2021-04-10