[1]丁聪聪,刘瑛琦,苏海鹏,等.西安地区0~~12 岁健康体检儿童血清25 羟维生素D 水平调查研究[J].现代检验医学杂志,2024,39(02):157-162.[doi:10.3969/j.issn.1671-7414.2024.02.029]
　DING Congcong,LIU Yingqi,SU Haipeng,et al.Research on Serum 25-Hydroxy Vitamin D Level in Healthy Children Aged 0~12 Years for Physical Examination in Xi’an Area[J].Journal of Modern Laboratory Medicine,2024,39(02):157-162.[doi:10.3969/j.issn.1671-7414.2024.02.029]
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西安地区0~~12 岁健康体检儿童血清25 羟维生素D 水平调查研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第39卷
期数:
2024年02期
页码:
157-162
栏目:
论著
出版日期:
2024-03-31

文章信息/Info

Title:
Research on Serum 25-Hydroxy Vitamin D Level in Healthy Children Aged 0~12 Years for Physical Examination in Xi’an Area
文章编号:
1671-7414（2024）02-157-06
作者:
丁聪聪1; 刘瑛琦2; 苏海鹏1; 张 靖1; 白重阳1
（1. 空军军医大学第二附属医院检验科，西安 710038；2. 空军军医大学基础医学院四大队，西安 710032）
Author(s):
DING Congcong1;  LIU Yingqi2;  SU Haipeng1;  ZHANG Jing1;  BAI Chongyang1
（1.Department of Laboratory Medicine, the Second Hospital of Air Force Medical University, Xi’an 710038, China; 2. No.4 Company, School of Basic Medical Sciences, Air Force Medical University, Xi’an 710032, China）
关键词:
血清25 羟维生素D; 西安地区; 儿童
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2024.02.029
文献标志码:
A
摘要:
目的　调查并评估西安地区0~12 岁体检儿童血清25 羟维生素D[25-hydroxy vitamin D，25（OH）D] 营养状况。方法　回顾性分析2020 年3 月1 日~2023 年7 月31 日空军军医大学第二附属医院儿童保健科进行常规体检的2 670 例西安市0~12 岁儿童的血清25（OH）D 资料，分析不同年龄、性别、季节儿童维生素D 的营养状况。结果　①该研究共纳入2 670 例西安市0~12 岁儿童，血清25（OH）D 均值为40.80 ± 18.00ng/ml，其中38 例（1.42%）存在血清25（OH）D 缺乏，333 例（12.47%）存在血清25（OH）D 不足，2 299 例（86.11%）血清25（OH）D 充足。②不同年龄段血清25（OH）D 差异有统计学意义（H=1 524.23，P=0.000）；1~<4 岁组最高，为52.51 ± 13.57ng/ml；8~12 岁组最低，为21.65 ± 6.75ng/ml。③夏季的血清25（OH）D 水平（39.44 ± 17.46ng/ml）低于春季（41.96 ± 17.76ng/ml）和秋季（42.71±18.15ng/ml），差异具有统计学意义（Z=101.57，-134.06，均P<0.01）。但冬季血清25（OH）D 缺乏、不足率（18.95%）高于春夏秋（13.52%，12.75%，12.36%）三季（χ2=14.32，P=0.026）。④不同性别血清25（OH）D 水平差异无统计学意义（H=0.933，P=0.351）。但男童血清25（OH）D 缺乏、不足率（12.51%）低于女童（15.46%），差异具有统计学意义（χ2=9.257，P=0.010）。结论　西安地区0~12 岁儿童维生素D 营养状况较好，应加强3 岁以上儿童维生素D 的摄入和补充。
Abstract:
Objective　To investigate and evaluate the nutrition status in serum 25-hydroxy vitamin D [25(OH)D] levels of 0~12 years old children in Xi’an. Methods　A total of 2 670 patients aged 0~12 years old who underwent routine physical examinations in Children’s Health Department of the Second Hospital of Air Force Medical University were selected from March 2020 to July 2023, and the 25(OH)D data of these patients were conducted in retrospective analysis. The nutritional status of vitamin D in these children of different genders, ages and seasons were also analyzed. Results　① This study included 2 670 children aged 0~12 years old in Xi'an, with the average level of serum 25(OH)D was 40.80 ± 18.00 ng/ml. Among them, 38 cases (1.42%) had serum 25(OH) D deficiency, 333 cases (12.47%) had serum 25(OH) D insufficience, and 2 299 cases (86.11%) had sufficient serum 25(OH)D. ② There was a statistically significant difference in serum 25(OH)D levels among different age groups (H=1 524.23, P=0.000). The group aged 1~<4 has the highest value of 52.51 ± 13.57 ng/ml, while the group aged 8~12 has the lowest value of 21.65 ± 6.75 ng/ml. ③ The levels of serum 25(OH)D in summer (39.44 ± 17.46 ng/ml) were lower than those in spring (41.96 ± 17.76 ng/ml) and autumn (42.71 ± 18.15 ng/ml), with statistical significant differences (Z=101.57, -134.06, all P<0.01). However, the deficiency and inadequate rate of serum 25(OH)D in winter (18.95%) was higher than those in spring, summer and autumn (13.52%, 12.75%, 12.36%), with statistical significant differences (χ2=14.32, P=0.026). ④ There was no statistically significant difference in serum 25(OH)D levels between genders (H=0.933, P=0.351). However, the deficiency and inadequate rate of serum 25(OH)D in boys (12.51%) was lower than that in girls (15.46%), and the difference was statistically significant (χ2=9.257, P=0.010). Conclusion　The nutritional status of serum 25(OH)D in children aged 0~12 years in Xi’an area is comparatively fine, and it is necessary to strengthen the intake and supplementation of vitamin D in over 3 years old children.

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备注/Memo

备注/Memo:
基金项目：唐都青年自主创新科学基金（2023CTDQN027）：CD73 通过STMN1 调控肝星状细胞自噬对肝纤维化的作用机制研究。
作者简介：丁聪聪（1994-），女，硕士，检验技师，主要从事临床检验工作，E-mail:1147240559@qq.com。
通讯作者：白重阳，男，副主任技师，E-mail：47213968@qq.com。
更新日期/Last Update: 2024-03-15