[1]李 栋,包安裕,宋 霖,等.血清蛋白与血脂检测结果实验室间互认的探讨[J].现代检验医学杂志,2015,30(01):159-162.[doi:10.3969/j.issn.1671-7414.2015.01.048]
 LI Dong,BAO An-yu,SONG Lin,et al.Exploration of Rutual Recognition of Results of Protein and Lipid ExamInation among Various Clinical Laboratories[J].Journal of Modern Laboratory Medicine,2015,30(01):159-162.[doi:10.3969/j.issn.1671-7414.2015.01.048]
点击复制

血清蛋白与血脂检测结果实验室间互认的探讨()
分享到:

《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年01期
页码:
159-162
栏目:
质量控制·实验室管理
出版日期:
2015-01-30

文章信息/Info

Title:
Exploration of Rutual Recognition of Results of Protein and Lipid ExamInation among Various Clinical Laboratories
文章编号:
1671-7414(2015)01-159-05
作者:
李 栋包安裕宋 霖陈 振
武汉大学人民医院检验科,武汉 430060
Author(s):
LI DongBAO An-yuSONG LinCHEN Zhen
Department of Clinical Laboratory, Renmin Hospital of Wuhan University,Wuhan 430060,China
关键词:
临床化学 血脂 互认
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2015.01.048
文献标志码:
A
摘要:
目的 通过在20家国家临床重点专科的检验科间开展蛋白与血脂检测结果的实验室间比对,探讨临床化学指标实验室间结果互认的可行性。方法 使用当前检测系统检测互认样品TP,ALB,TC和TG浓度,统计各实验室的检测结果,并比较使用校准品对各实验室结果进行公式校准前后的结果。根据校准前后百分差值、稳健Z比分数和医学决定水平处的偏倚评价互认可行性。结果 汇总检测数据,根据稳健Z比分数、校准前后百分差值、医学决定水平处的偏倚等指标反映检测结果。TG的百分差值变化大,可从-40%变化至30%; TC在3个浓度水平处均达到了适当允许偏倚的标准,TG主要满足最低的允许偏倚。结论 临床化学脂类指标在实验室间互认尚需完善检测系统标准化,才能保证实验室间互认的有效性。
Abstract:
Objective To explore the possibility and reliability of mutual recognition of renal indexs among 20 clinical laboratories entitled with state key clinical laboratory,and to supply reference for future national mutual recognition of laboratory examination results.Methods Determined the concentrations of TP,ALB,TC,TG and Roche multiple calibrators and submitted the results.The results were analyzed for robust Z score,percentage difference after calibration,bias at medical decision level to observe the possibility and reliability.Results The bias ofTG was out of the least allowable bias,thus they were not appropriate to mutual recognition.Conclusion It remains immature in the mutual recognition of lipids' determinations and much work needs to be done in field of internal quality control of the laboratory.

参考文献/References:

[1] 吴时耕,张 鹰,万本愿,等.县级以上医院实验室质量控制与检验结果相互认可的研究[J].实验与检验医学,2011,29(5):519-522.
[2] 雷良华,万本愿,吴时耕,等.医疗机构间检验结果互认的可行性研究[J].卫生经济研究,2013(4):39-42.
[3] 李 栋,包安裕,宋 霖,等.临床化学酶学指标实验室间结果互认的探讨[J].现代检验医学杂志,2012,27(5):83-88. Li D,Bao AY,Song L,et al.Exploration of mutual recognition of results of enzymatic determinations among various clinical laboratories[J].J Mod Lab Med,2012,27(5):83-88.
[4] 周 琦,谢 伟,徐建平,等.利用稳健Z比分数评价肌酐能力验证的数据[J].中华检验医学杂志,2011,34(12):1144-1148. Zhu Q,Xie W,Xu JP,et al.Use of robust Z-sore to assess creatinie proficiency testing data[J].Chinese Journal of Laboratory Medicine,2011,34(12):1144-1148.
[5] Rizk MM,El-Badawi NA,Moez PE,et al.Implementation of quality controlperformance criteria and approved guidelines for upgrading of clinical chemistry laboratory procedures in Alexandria University hospitals[J].Clin Biochem,2009,42(4/5):288-292.
[6] Ohno H.Significance and future prospects of the IS O15189 accreditationtopics on systems of operation in preparation for accreditation[J].Rinsho Byori,2010,58(1):69-72.
[7] Dobler CC,Marks GB.Medical decision making at the individual patient level[J].Arch Intern Med,2010,170(14):1275-1276.
[8] 杨振华.参考体系是检验结果通用的科学基础[J].中国医院,2006,10(6):4-6. Yang ZH.Reference system was the scientific fundamental for commonusing the examination result[J].Chinese Hospitals,2006,10(6):4-6.
[9] Simundic AM,Cornes MP,Grankvist K,et al.Standardization of collectionrequirements for fasting samples:For the working group on preanalytical phase(WG-PA)of the european federation of clinical chemistry and laboratory medicine(EFLM)[J].Clin Chim Acta,2014(432):33-37.

相似文献/References:

[1]陈 宇,倪二茹,杨 新,等.福州市公交司机血糖、尿酸和血脂的调查研究[J].现代检验医学杂志,2016,31(01):149.[doi:10.3969/j.issn.1671-7414.2016.01.044]
 CHEN-Yu,NI Er-ru,YANG Xin,et al.Investigation on Serum Glucose,Uric Acid and Lipid Profile of Professional Bus Drivers in Fuzhou City[J].Journal of Modern Laboratory Medicine,2016,31(01):149.[doi:10.3969/j.issn.1671-7414.2016.01.044]
[2]赵 佳a,左 林b,姚创利a,等.锰超氧化物歧化酶基因变异 与血脂和同型半胱氨酸水平的关系研究[J].现代检验医学杂志,2016,31(03):12.[doi:10.3969/j.issn.1671-7414.2016.03.004]
 ZHAO Jiaa,ZUO Linb,YAO Chuang-lia,et al.Study on the Relationship between Manganese Superoxide Dismutase Gene Variants and the Levels of Blood Lipid and Homocysteine[J].Journal of Modern Laboratory Medicine,2016,31(01):12.[doi:10.3969/j.issn.1671-7414.2016.03.004]
[3]张允奇a,陆学东b,张银辉b,等.SLE患者血清胱抑素C与血脂的相关性分析[J].现代检验医学杂志,2015,30(04):63.[doi:10.3969/j.issn.1671-7414.2015.04.017]
 ZHANG Yun-qia,LU Xue-dongb,ZHANG Yin-huib,et al.Correlation Analysis of Serum Cystatin C and Lipids Levels in Patients with Systemic Lupus Erythematosus[J].Journal of Modern Laboratory Medicine,2015,30(01):63.[doi:10.3969/j.issn.1671-7414.2015.04.017]
[4]李友建,顾桂兰,王志勇,等.同型半胱氨酸、糖化血红蛋白和血脂与后循环缺血的相关性研究[J].现代检验医学杂志,2015,30(02):132.[doi:10.3969/j.issn.1671-7414.2015.02.041]
 LI You-jian,GU Gui-lan,WANG Zhi-yong,et al.Relationship between Homocysteine,Glycosylated Hemoglobin, Lipids and Posterior Circulation Ischemia[J].Journal of Modern Laboratory Medicine,2015,30(01):132.[doi:10.3969/j.issn.1671-7414.2015.02.041]
[5]潘莉兰,邓 盼,祝卫平.湖北省临床化学常规检验项目不精密度分析[J].现代检验医学杂志,2015,30(02):160.[doi:10.3969/j.issn.1671-7414.2015.02.051]
 PAN Li-lan,DENG Pan,ZHU Wei-ping.Analysis of the Imprecision of Clinical Routine Chemistry Analysis Tests in Hubei Province[J].Journal of Modern Laboratory Medicine,2015,30(01):160.[doi:10.3969/j.issn.1671-7414.2015.02.051]
[6]宋令雄,张 燕,张明威,等.儿童原发性肾病综合征患者血清补体C1q水平变化及其临床意义[J].现代检验医学杂志,2017,32(04):1.[doi:10.3969/j.issn.1671-7414.2017.04.001]
 SONG Ling-xiong,ZHANG Yan,ZHANG Ming-wei,et al.Study on Serum Levels of C1q and Their Clinical Significance in Children with Nephrotic Syndrome[J].Journal of Modern Laboratory Medicine,2017,32(01):1.[doi:10.3969/j.issn.1671-7414.2017.04.001]
[7]杜 洁,杨 维,张桂侠,等.幽门螺杆菌感染与血脂代谢及动脉粥样硬化的相关性[J].现代检验医学杂志,2017,32(04):104.[doi:10.3969/j.issn.1671-7414.2017.04.029]
 DU Jie,YANG Wei,ZHANG Gui-xia,et al.Relationship between Helicobacter Pylori Infection and Blood Lipid Metabolism and Atherosclerosis[J].Journal of Modern Laboratory Medicine,2017,32(01):104.[doi:10.3969/j.issn.1671-7414.2017.04.029]
[8]张同庆,杨文东.急性脑梗死并发幽门螺旋杆菌感染者血脂水平及氧化应激反应的观察[J].现代检验医学杂志,2018,33(02):66.[doi:10.3969/j.issn.1671-7414.2018.02.001]
 ZHANG Tong-qing,YANG Wen-dong.Observation of Serum Lipid Level and Oxidative Stress Response in Patients with Acute Cerebral Infarction Complicated with Helicobacter Pylori Infection[J].Journal of Modern Laboratory Medicine,2018,33(01):66.[doi:10.3969/j.issn.1671-7414.2018.02.001]
[9]冯 杰,于 帆,高艳红,等.乙状结肠癌患者血脂水平变化及其诊断价值探究[J].现代检验医学杂志,2018,33(03):74.[doi:10.3969/j.issn.1671-7414.2018.03.019]
 FENG Jie,YU Fan,GAO Yan-hong,et al.Invesgation of the Serum Lipids Level Changes and Its' Diagnostic Value in Sigmoid Colon Cancer[J].Journal of Modern Laboratory Medicine,2018,33(01):74.[doi:10.3969/j.issn.1671-7414.2018.03.019]
[10]苗玉发,张河战.43家食品药品检测机构实验室检测6项生化指标能力验证评价[J].现代检验医学杂志,2018,33(03):158.[doi:10.3969/j.issn.1671-7414.2018.03.041]
 MIAO Yu-fa,ZHANG He-zhan.Proficiency Testing Evaluation on Determination of 6 BiochemicalIndices in 43 Chinese Laboratories of Food and Drug Control Institutions[J].Journal of Modern Laboratory Medicine,2018,33(01):158.[doi:10.3969/j.issn.1671-7414.2018.03.041]

备注/Memo

备注/Memo:
基金项目:国家临床检验重点专科建设项目资助,项目编号:财社
[2010]305。
作者简介:李 栋(1964-),男,本科,副主任技师,研究方向:临床化学检验、实验室管理,E-mail:dongdongli427@163.com。
更新日期/Last Update: 2015-01-30