[1]潘秀林a,朱玩秀b.妊高症患者血清CysC,HCY及mALB联合检测的临床意义[J].现代检验医学杂志,2015,30(03):145-146.[doi:10.3969/j.issn.1671-7414.2015.03.044]
　PAN Xiu-lina,ZHU Wan-xiub.Clinical Significance of Serum Cys C,HCY and mALB Joint Detection to HDCP Patients[J].Journal of Modern Laboratory Medicine,2015,30(03):145-146.[doi:10.3969/j.issn.1671-7414.2015.03.044]
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妊高症患者血清CysC,HCY及mALB联合检测的临床意义()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年03期
页码:
145-146
栏目:
检验与临床
出版日期:
2015-06-10

文章信息/Info

Title:
Clinical Significance of Serum Cys C,HCY and mALB Joint Detection to HDCP Patients
文章编号:
1671-7414(2015)03-145-03
作者:
潘秀林a; 朱玩秀b
广西贺州广济医院 a.检验科; b.产科,广西贺州 542899
Author(s):
PAN Xiu-lina; ZHU Wan-xiub
a.Department of Clinical Laboratory;
b.Department of Obstetrics,Guangji Hospital of Hezhou,Guangxi Hezhou 542899,China
关键词:
妊高症;  肾功能;  增强比浊法;  免疫散射法
分类号:
R714.246; R446.112
DOI:
10.3969/j.issn.1671-7414.2015.03.044
文献标志码:
A
摘要:
目的 探讨妊娠高血压综合症患者血清Cys C,Hcy及mAlb联合检测的临床意义。方法 选取2011年6月～2014年6月广西贺州广济医院诊治的92例妊高症患者作为观察组,分为A,B,C三组(A组为HDCP患者43例,B组为轻度子痫前期患者32例,C组为重度子痫前期患者17例),另选该院同期50例健康产妇作为对照组。测定血清Cys C,Hcy(采用增强比浊法)以及尿mAlb(采用免疫散射法),对结果进行统计分析。结果 观察组血清Cys C,Hcy及尿mAlb水平随着肾功能受损害程度的加重而升高,以观察组C升高最为显著(F=4.567,P＜0.001); 观察组血清Cys C,Hcy及尿mAlb水平异常检出率随着肾功能受损害程度的加重而升高,以观察组C升高最为显著(χ2=12.842,P＜0.001); 三项联合检测指标异常检出率显著高于单项检测(χ2=5.869,P＜0.001),检测敏感度为95.70%,具有显著优势(χ2=15.992,P＜0.001)。结论 HDCP患者肾功能血清Cys C,Hcy及mAlb联合检测结果显著优于单项检测,有利于妊高症肾功能损伤的早期诊断,值得临床推广。
Abstract:
Objective To analysis clinical significance ofjoint detection of serum Cys C,Hcy and mAlb in HDCP patients.Methods Selected 92 cases of HDCP patients in Guangji hosipital of Hezhoufrom Jun 2011 to Jun 2014 as observation group.They were divided into three groups(43 patients of gestational hypertension as group A,32 patients with mild preeclampsia as group B,17 patients of severe preeclampsia as group C)and chose50 cases of healthy maternal the same period in the hospital as control group.Enhanced turbidimetric method for the determination of serum Cys C,Hcy,immunescattering method for urinary mAlb,the results were analyzed.Results Observation group with the level of serum Cys C,Hcy and urinary mAlb was rise with the damage degree aggravating,group C rise significantly(F=4.567,P＜0.001).Observation group serum Cys C,Hcy and abnormal detectionrate of urinary mAlb level was rise at the same time renal damage degree aggravating,group C rise significantly(χ2=12.842,P＜0.001).Three joint detection indices abnormal detection rate was significantly higher than that of single detection(χ2=5.869,P＜0.001),the detection sensitivity of 95.70% has significant advantage(χ2=15.992,P＜0.001).Conclusion The joint detection of renal function of serum Cys C,Hcy and mAlb in HDCP patients was better than the single detection,which is helpful for the early detection of HDCP patients with renal damage,it's worthy clinical promotion.

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备注/Memo

备注/Memo:
作者简介:潘秀林(1964-),男,大专学历,主管检验师,检验科主任,从事免疫检验工作,Tel:15077345337,E-mail:406228703@qq.com。
更新日期/Last Update: 2015-06-10