[1]张 华,詹 颉,苍金荣,等.TGC,MH和PB对泛耐药鲍曼不动杆菌的体外抗菌活性观察[J].现代检验医学杂志,2015,30(04):93-95.[doi:10.3969/j.issn.1671-7414.2015.04.026]
　ZHANG Hua,ZHAN Jie,CANG Jin-rong,et al.Antibacterial Activity Observation of TGC, MH and PB on the Pan-resistant Acinetobacter Baumannii in Vitro[J].Journal of Modern Laboratory Medicine,2015,30(04):93-95.[doi:10.3969/j.issn.1671-7414.2015.04.026]
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TGC,MH和PB对泛耐药鲍曼不动杆菌的体外抗菌活性观察()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年04期
页码:
93-95
栏目:
论著
出版日期:
2015-08-10

文章信息/Info

Title:
Antibacterial Activity Observation of TGC, MH and PB on the Pan-resistant Acinetobacter Baumannii in Vitro
文章编号:
1671-7414(2015)04-093-03
作者:
张 华1; 詹 颉1; 苍金荣1; 付 子2; 归巧娣1; 刘 英1; 陈 苗1; 宫艳艳1
陕西省人民医院检验科,西安 710068;
2.西安铁路工程医院,西安 710600
Author(s):
ZHANG Hua1; ZHAN Jie1; CANG Jin-rong1; FU Zi2; GUI Qiao-di1; LIU Ying1; CHEN Miao1;  Gong Yan-yan1
1.Department of Clinical Laboratory,Shaanxi Province People's Hospital, Xi'an 710068,China;
2.Xi'an Railway Engineering Hospital,Xi'an 710600,China
关键词:
替加环素;  米诺环素;  多黏菌素B;  泛耐药鲍曼不动杆菌;  体外抗菌活性
分类号:
R378; R446.5
DOI:
10.3969/j.issn.1671-7414.2015.04.026
文献标志码:
A
摘要:
目的 观察替加环素(TGC)、米诺环素(MH)和多黏菌素B(PB)对泛耐药鲍曼不动杆菌(PDR-Ab)的体外抗菌活性,为临床治疗和控制感染提供参考依据。方法 对2013年10月至2014年3月陕西省人民医院住院及门诊患者临床标本分离并鉴定的非重复计数的76株泛耐药鲍曼不动杆菌进行替加环素、米诺环素和多黏菌素B的纸片扩散法(K-B)药敏试验。结果 泛耐药鲍曼不动杆菌分布最多的是ICU,占总数的44.7%,其次是呼吸内科,占总数的22.4%。标本来源最多的是痰液,占总数的85.5%,其次是灌洗液,占总数的9.2%,尿液、脑脊液、关节液和腹腔积液各占总数的1.3%。76株泛耐药鲍曼不动杆菌,对替加环素和多黏菌素B的敏感率均为100%,对米诺环素敏感率和中介率分别为67.11% 和27.63%。结论 替加环素、米诺环素和多黏菌素B对泛耐药鲍曼不动杆菌具有良好的体外抗菌活性,可为临床泛耐药鲍曼不动杆菌引起的感染性疾病的治疗提供参考依据。
Abstract:
Objective To observe tigecycline(TGC),minocycline(MH)and polymyxin B(PB)in vitro antibacterial activity of pan-resistantAcinetobacter baumannii(PDR-Ab)for clinical treatment,provide the basisfor infection control.Methods Collected 76 patients' clinical specimens used for no repeat count of isolation and identification withpan-resistant Acinetobacter baumannii in Shaanxi Provincial People's Hospital from October 2013 to March 2013.Used tigecycline,minocycline and polymyxinB to do susceptibility testing with disk diffusion method(KB).Results 76 pan-resistant Acinetobacter baumannii,sensitive to the rate for tigecycline and polymyxin B were 100% sensitivity rate of minocyclineand intermediary rates were 67.11%,27.63%.Conclusion Tigecycline,minocycline and polymyxin B for the Pan-resistant Acinetobacter baumannii had good in vitro antibacterial activity.It provide a reference for clinical pan-resistant Acinetobacter baumannii infections caused by diseases treatment.

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备注/Memo

备注/Memo:
作者简介:张 华(1966-),女,大专,主管检验师。
通讯作者:苍金荣(1962-),女,副主任检验师,Tel:13892805820,E-mail:Cang1963@163.com。
更新日期/Last Update: 2015-08-10