[1]刘苑欢,刘爱胜,文 艳.不同类型慢性肝炎人群戊型病毒性肝炎感染率现状调查研究[J].现代检验医学杂志,2016,31(01):152-154.[doi:10.3969/j.issn.1671-7414.2016.01.045]
　LIU Yuan-huan,LIU Ai-sheng,WEN Yan.Prevalence Situation Investigation and Study on E Viral Hepatitis in Different Types of Chronic Hepatitis[J].Journal of Modern Laboratory Medicine,2016,31(01):152-154.[doi:10.3969/j.issn.1671-7414.2016.01.045]
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不同类型慢性肝炎人群戊型病毒性肝炎感染率现状调查研究()

《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年01期
页码:
152-154
栏目:
检验与临床
出版日期:
2016-01-25

文章信息/Info

Title:
Prevalence Situation Investigation and Study on E Viral Hepatitis in Different Types of Chronic Hepatitis
作者:
刘苑欢1,刘爱胜1,文 艳2
1.深圳市龙华新区人民医院检验科,广东深圳 518109; 2.深圳市光明新区人民医院ICU,广东深圳 518106
Author(s):
LIU Yuan-huan1,LIU Ai-sheng1,WEN Yan2
1.Department of Clinical Laboratory, Shenzhen Longhua New District People's Hospital,Guangdong Shenzhen 518109,China; 2.ICU Shenzhen Guangming New District People's Hospital,Guangdong Shenzhen518106,China
关键词:
戊型病毒性肝炎;  乙型病毒性肝炎;  丙型病毒性肝炎;  感染率
分类号:
R512.65; R446.6
DOI:
10.3969/j.issn.1671-7414.2016.01.045
文献标志码:
A
摘要:
目的 了解深圳地区不同类型慢性肝炎人群戊型病毒性(Hepatitis E/HE)肝炎(戊肝)感染现状,为戊肝的预防和治疗提供科学依据。方法随机收集2013年7月～2015年6月来深圳市龙华新区人民医院体检及就诊的无肝炎正常人群1 746例为对照组,慢性乙型病毒性肝炎(乙肝)人群1 320例为乙肝组,慢性丙型病毒性肝炎(丙肝)人群615例为丙肝组,分别应用酶联免疫吸附试验法(ELISA)检测血清中戊肝抗体-IgG(抗HEV-IgG),分析不同类型肝炎人群戊肝感染情况,并比较不同组间戊肝感染率是否存在差异性。结果 1 746例对照组血清中抗HEV-IgG阳性率为3.49%,其中男性4.22%,女性2.68%; 1 320例乙肝组为10.9%,其中男性12.29%,女性8.23%; 615例丙肝组为10.2%,其中男性12.35%,女性7.64%。乙肝组和丙肝组抗HEV-IgG阳性率与对照组比较差异有统计学意义(χ2=9.163～9.405,P<0.05),乙肝组与丙肝组抗HEV-IgG阳性率之间差异无统计学意义(χ2=0.614,P>0.05),戊肝男性感染率高于女性,差异有统计学意义(χ2 =2.873～4.025,P<0.05)。结论 慢性乙型病毒性肝炎和丙型病毒性肝炎人群抗HEV-IgG阳性率高于无肝炎正常人群,戊肝感染率男性高于女性。因此,加强对慢性乙型病毒性肝炎和丙型病毒性肝炎人群的早发现、早诊断和早治疗,对降低戊肝感染率有重要的意义。
Abstract:
Objective To understand the different types ofchronic hepatitis group in shenzhen area E viral hepatitis(hepatitis E infection status and provide scientific basis for the prevention and treatment of hepatitis E.Methods Randomly collected from July 2013 to June2015 in shenahen Longhua New District People's Hospital without hepatitis normal physical examination and treatment group 1746 cases as control group,chronichepatitis B viral hepatitis(hepatitis B)the crowd of 1 320 cases of hepatitisB,chronic viral hepatitis C(HCV)population group,615 cases of hepatitis C,respectively,the application method of enzyme-linked immunosorbent assay(ELISA)to detect serum hepatitis E antibody(anti HEV IgG)-IgG,analyzed of different types of hepatitis a crowd hepatitise infection status,and compared the hepatitise infection rate if there was a difference between the different groups.Results 1 746 cases of control group in serum anti HEV-IgGpositive rate was 3.49%(61/1 746),4.22% of men and women in 2.68%.1 320 cases of hepatitis B group was 10.9%,12.29% of men and women in 8.23%.615 cases of C group was 10.2%,12.35% of men and women in 7.64%.Hepatitis B and Cgroup of HEV-IgG positive rate compared with control group difference was statistically significant(χ2=9.163～9.405,P<0.05),and hepatitis B and hepatitis C group there was no statistically significant difference between positive HEV-resistant IgG(χ2=0.614,P>0.614),and hepatitis E infection rate than women,men was statistically significant difference(χ2=2.873～4.025,P<0.05).Conclusion Chronic hepatitis B and C viralhepatitis crowd anti HEV-IgG positive rate was higher than normal people,no hepatitis hepatitis E infection rate among men than women.Therefore,strengthensto the chronic hepatitis B and C viral hepatitis a crowd of early discovery,early diagnosis and early treatment,to reduce hepatitis E infection rate has an important significance.

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备注/Memo

备注/Memo:
作者简介:刘苑欢(1983-),女,本科,学士,主管技师,主要从事免疫生化与临检工作。
更新日期/Last Update: 2016-01-20