[1]杨本善,舒 杨,文江平,等.北京市老年人群血清铁、总铁结合力参考区间调查[J].现代检验医学杂志,2017,32(02):138-140.[doi:10.3969/j.issn.1671-7414.2017.02.038]
　YANG Ben-shan,SHU Yang,WEN Jiang-ping,et al.Investigation for the Reference Intervals of Serum Iron and Total Iron Binding Capacity among 60+ Years People in Beijing[J].Journal of Modern Laboratory Medicine,2017,32(02):138-140.[doi:10.3969/j.issn.1671-7414.2017.02.038]
点击复制

北京市老年人群血清铁、总铁结合力参考区间调查()
分享到：

《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年02期
页码:
138-140
栏目:
研究简报·实验技术
出版日期:
2017-03-25

文章信息/Info

Title:
Investigation for the Reference Intervals of Serum Iron and Total Iron Binding Capacity among 60+ Years People in Beijing
文章编号:
1671-7414(2017)02-138-03
作者:
杨本善; 舒 杨; 文江平; 刘向祎
首都医科大学附属北京同仁医院检验科,北京 100730
Author(s):
YANG Ben-shan; SHU Yang; WEN Jiang-ping; LIU Xiang-yi
Department of Medical Laboratory, Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing100730,China
关键词:
老年人;  血清铁;  总铁结合力;  参考值
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2017.02.038
文献标志码:
A
摘要:
目的 探讨北京市老年人群60～79岁血清铁、总铁结合力的参考区间,为临床提供诊断依据。方法 收集2014年9月～2015年3月首都医科大学附属北京同仁医院340例60～79岁老年健康体检者的血清标本,其中男性167例,女性173例,采用美国贝克曼库尔特公司的DXC-800(络合法)检测血清铁、总铁结合力,并对两种指标进行比较分析。结果 男性血清铁含量为17.45±5.67 μmol/L,女性血清铁含量为17.52±6.2 μmol/L,二者比较差异无统计学意义(t=1.32,P>0.05),北京市老年人群血清铁的参考区间为7.9～23.1 μmol/L; 男性总铁结合力的含量为50.78±9.17 μmol/L,女性总铁结合力的含量为52.17±9.75 μmol/L,二者比较差异无统计学意义(t=1.75,P>0.05),老年人群总铁结合力的参考区间为37.8～62.2 μmol/L。结论 北京地区老年人男女之间血清铁、总铁结合力无统计学差异,该研究调查得出北京市老年人血清铁、总铁结合力的参考区间,有一定的临床应用参考价值。
Abstract:
Objective To establish the reference intervalsof serum iron and total iron binding capacity(TIBC)among 60+ years people inBeijing.Methods Collected Beijing TongRen Hospital,Capital Medical University from 60 to 79 year-old male 167 cases,173 cases of female serum samples of healthy subjects using Beckman's DXC-800 serum iron,total iron binding capacity,and comparative analysis of two kinds of indicators.Results The normal reference range of serum iron in Beijing(60 to 79 years)was 7.9～23.1 μmol/L.The values were 17.45±5.67 μmol/L in male,and 17.52±6.2 μmol/L in female(t=1.32,P >0.05).The normal reference range of total iron binding capacity was 37.8～62.2 μmol/L.The values were 50.78±9.17 μmol/L in male,and 52.17±9.75 μmol/L in female(t=1.75,P>0.05).Conclusion There was no significant difference between serum iron and total iron binding capacity in elderlymen and women.The investigation gave the reference intervals of serum iron andtotal iron binding capacity in Beijing Han elderly(60 to 79 years),which can provide useful reference to clinical.

参考文献/References:

[1] 杨 阳,张 艳,罗 浪,等.铁代谢异常与人体疾病研究进展[J].吉林医学,2011,32(2):328-331.
[2] Zwart SR,Morgan JL,Smith SM,et al.Iron status and its relations with oxidative damage and bone loss during long-duration space flight onthe International Space Station[J].American Journal of Clinical Nutrition,2013,98(1):217-223.
[3] Liu K,Kaffes AJ.Iron deficiency anaemia:a review of diagnosis,investigation and management[J].Eur J Gastroenterol Hepatol,2012,24(2):109-116.
[4] Khanbhai M,Dubb S,Patel K,et al.The prevalence of iron deficiency anaemia in patients undergoing bariatric surgery[J].Obes Res Clin Pract,2015,9(1):45-49.
[5] 曾 洁,陈文祥,申子瑜.参考区间研究现状概述[J].中华检验医学杂志,2010,33(6):570-573.
[6] 王治国.临床检验生物学变异与参考区间[M].北京:人民卫生出版社,2012.
[7] Ludwing H,Müldür E,Endler G,et al.Prevalence of iron deficiency across different tumors and its association with poor performance status,diseasestatus and anemia[J].Ann Oncol,2013,24(7):1886-1892.
[8] 徐淑静,孙 雪,孙 燕,等.初发2型糖尿病患者铁代谢指标的变化及分析[J].中华内科杂志,2013,52(1):49-50.
[9] 王 薇,钟 堃,白 玉,等.全国常规化学检验项目参考区间现状调查分析[J].中华检验医学杂志,2011,34(12):1139-1143. Wang W,Zhong K,Bai Y,et al.Investigation and analysis of reference intervals of routine clinical assays in China[J].Chin J Lab Med,2011,34(12):1139-1143.

相似文献/References:

[1]段发兰a,李亚新b,杨飞翔a,等.2型糖尿病患者血清铁代谢相关指标检测意义[J].现代检验医学杂志,2015,30(03):151.[doi:10.3969/j.issn.1671-7414.2015.03.046]
　Study on Iron Metabolism in Type Diabetes Patients.Study on Iron Metabolism in Type 2 Diabetes Patients[J].Journal of Modern Laboratory Medicine,2015,30(02):151.[doi:10.3969/j.issn.1671-7414.2015.03.046]
[2]王艳霞,肖景华,李亚妮,等.孕妇血清铁、锌微量元素与妊娠期高血压疾病的关系[J].现代检验医学杂志,2019,34(02):130.[doi:10.3969/j.issn.1671-7414.2019.02.033]
　WANG Yan-xia,XIAO Jing-hua,LI Ya-ni,et al.Study on the Relationship between Serum Iron and Zinc Trace Elementsin Pregnant Women and Hypertensive Disorders in Pregnancy[J].Journal of Modern Laboratory Medicine,2019,34(02):130.[doi:10.3969/j.issn.1671-7414.2019.02.033]
[3]于　莉,张　敏,张小华,等.老年脓毒症患者血清miR-206及miR-451水平与疾病严重程度和预后的相关性研究[J].现代检验医学杂志,2022,37(03):96.[doi:10.3969/j.issn.1671-7414.2022.03.020]
　YU Li,ZHANG Min,ZHANG Xiao-hua,et al.Correlation of Serum miR-206 and miR-451 Levels with Disease Severity and Prognosis in Elderly Patients with Sepsis[J].Journal of Modern Laboratory Medicine,2022,37(02):96.[doi:10.3969/j.issn.1671-7414.2022.03.020]
[4]黄 英a,张 燕a,周朝琼a,等.基于生物学变异建立老年人血清总蛋白和清蛋白水平个性化参考区间及应用[J].现代检验医学杂志,2023,38(02):146.[doi:10.3969/j.issn.1671-7414.2023.02.027 ]
　HUANG Yinga,ZHANG Yana,ZHOU Chao-qionga,et al.Establish Serum Total Protein and Albumin Levels in the Elderly Based on Biological Variation Personalized Reference Interval and Application[J].Journal of Modern Laboratory Medicine,2023,38(02):146.[doi:10.3969/j.issn.1671-7414.2023.02.027 ]

备注/Memo

备注/Memo:

作者简介:杨本善(1964-),男,学士学位,中级职称,研究方向:生物化学和免疫学,E-mail:yangbenshan2004@163.com。
更新日期/Last Update: 2017-04-10