[1]杜 洁,杨 维,张桂侠,等.幽门螺杆菌感染与血脂代谢及动脉粥样硬化的相关性[J].现代检验医学杂志,2017,32(04):104-106.[doi:10.3969/j.issn.1671-7414.2017.04.029]
　DU Jie,YANG Wei,ZHANG Gui-xia,et al.Relationship between Helicobacter Pylori Infection and Blood Lipid Metabolism and Atherosclerosis[J].Journal of Modern Laboratory Medicine,2017,32(04):104-106.[doi:10.3969/j.issn.1671-7414.2017.04.029]
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幽门螺杆菌感染与血脂代谢及动脉粥样硬化的相关性()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年04期
页码:
104-106
栏目:
论著
出版日期:
2017-07-25

文章信息/Info

Title:
Relationship between Helicobacter Pylori Infection and Blood Lipid Metabolism and Atherosclerosis
文章编号:
1671-7414(2017)04-104-03
作者:
杜 洁1; 杨 维2; 张桂侠1; 何秋仙1; 李红艳1; 隋永杰1
1.陕西省人民医院健康体检中心, 西安 710068; 2.西安市中医医院检验科,西安 710021
Author(s):
DU Jie1; YANG Wei2; ZHANG Gui-xia1; HE Qiu-xian1; LI Hong-yan1; SUI Yong-jie1
1.Physical Examination Center,Shaanxi Provincial People's Hospital,Xi'an 710068,China; 2.Department of Clinical Laboratory,Xi'an Traditional Chinese Medicine Hospital,Xi'an 710021,China
关键词:
幽门螺杆菌;  血脂;  动脉粥样硬化
分类号:
R378.2; R446.112
DOI:
10.3969/j.issn.1671-7414.2017.04.029
文献标志码:
A
摘要:
目的 探讨幽门螺杆菌(Hp)感染与血脂代谢及动脉粥样硬化的相关性。方法 选取2015年10月～2016年10月200例检测Hp阳性体检者为观察组和200例Hp阴性体检者为对照组,对所有受检者进行血脂水平及血管超声等相关检查。结果 观察组患者的总胆固醇(TC)水平(5.68±1.46 mmol/L)、三酰甘油(TG)水平(1.58±0.76 mmol/L)及低密度脂蛋白胆固醇(LDL-C)水平(3.36±0.89 mmol/L)高于对照组(4.86±1.21,1.06±0.58,2.93±0.61 mmol/L),差异均具有统计学意义(t=6.12,7.69,5.64,均P<0.05); 观察组患者的颈动脉粥样硬化斑块的检出率为66.00%,明显高于对照组49.50%,差异具有统计学意义(χ2 =29.61,P<0.05),其中观察组患者的不稳定斑块检出率为44.5%,明显高于对照组(22.5%),差异具有统计学意义(χ2 =21.73,P<0.05)。结论 Hp感染与患者体内血脂代谢水平有一定的相关性,是动脉粥样硬化发生及发展的重要因素。
Abstract:
Objective To investigate the correlation between Helicobacter pylori(Hp)infection and blood lipid metabolism and atherosclerosis.Methods From October 2015 to October 2020,200 cases of Hp positive subjects were observed as observation group and 200 cases ofHp negative subjects as the control group,all subjects were blood lipid levelsof vascular ultrasound and other related checks.Results The levels of total cholesterol(TC)(5.68±1.46 mmol/L),triglyceride(TG)(1.58±0.76 mmol/L)and low density lipoprotein cholesterol(LDL-C),and the difference was statistically significant(t=6.12,7.69,5.64,all P<0.05).The detection rate of carotid atherosclerotic plaque in the observation group was 66.00%,which was significantly higher than that in the control group(49.50%),the difference was statistically significant(χ2=29.61,P<0.05),and the observation group.The detection rate of stable plaque was 44.5%,which was significantly higher than that of the control group 22.5%,the difference was statistically significant(χ2=21.73,P<0.05).Conclusion Hp infection can affect the level of lipid metabolism in patients,which is an important factor in the occurrence and development of atherosclerosis.

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备注/Memo

备注/Memo:
基金项目:中国健康促进基金会项目(项目编号:2010003)。 作者简介:杜 洁(1983-),女,硕士,主治医师,主要从事健康体检管理工作,E-mail:dujie123._@163.com。 通讯作者:杨 维,女,硕士,主管检验师,E-mail:95250473@qq.com。
更新日期/Last Update: 1900-01-01