[1]归巧娣,刘文康,任健康,等.鲍曼不动杆菌在ICU病房传播途径及耐药性研究[J].现代检验医学杂志,2017,32(06):109-111.[doi:10.3969/j.issn.1671-7414.2017.06.001]
 GUI Qiao-di,LIU Wen-kang,REN Jian-kang,et al.Transmission and Analysis of Drug Resistance of Acinetobacter Baumanii in ICU[J].Journal of Modern Laboratory Medicine,2017,32(06):109-111.[doi:10.3969/j.issn.1671-7414.2017.06.001]
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鲍曼不动杆菌在ICU病房传播途径及耐药性研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年06期
页码:
109-111
栏目:
论著
出版日期:
2017-12-25

文章信息/Info

Title:
Transmission and Analysis of Drug Resistance of Acinetobacter Baumanii in ICU
文章编号:
1671-7414(2017)06-109-03
作者:
归巧娣刘文康任健康苍金荣宫艳艳王 华
陕西省人民医院检验科,西安 710068
Author(s):
GUI Qiao-diLIU Wen-kangREN Jian-kangCANG Jin-rongGONG Yan-yanWANG Hua
Department of Clinical Laboratory,Shaanxi Provincial People'sHospital,Xi'an 710068,China
关键词:
鲍曼不动杆菌重症监护病房传播
分类号:
R378; R446.5
DOI:
10.3969/j.issn.1671-7414.2017.06.001
文献标志码:
A
摘要:
目的 通过检测鲍曼不动杆菌在ICU病房的分布及其同源性分析,明确鲍曼不动杆菌在ICU病房传播及途径,为控制医院内感染,采取有效措施提供理论依据。方法 对2016年1月新进入陕西省人民医院ICU,排除入组前感染鲍曼不动杆菌的20例患者作为研究对象,采用前瞻性方法定期采集病人痰标本和其周围环境标本进行培养,了解鲍曼不动杆菌在ICU病房的分布。同时采用MALDI-TOF质谱进行同源性分析及K-B法进行药敏试验。结果 共分离27株鲍曼不动杆菌,主要来源于痰、医护人员手和环境,同源性分析结果显示27株鲍曼不动杆菌分为2大簇(Ⅰ型11株,Ⅱ型16株),大多数鲍曼不动杆菌均为多重耐药菌,除多黏菌素B、米诺环素和头孢哌酮/舒巴坦外耐药率均超过90%。结论 鲍曼不动杆菌在ICU病房通过医护人员手、污染的医疗器械传播,加强消毒及合理应用抗菌药物,有利于防控鲍曼不动杆菌感染及传播。
Abstract:
Abstract:Objective By detecting the distribution and homology analysis of Acinetobacter baumanii in the ICU ward,to control nosocomial infection,provide theoretical basis to take effective measures.Methods From January 2016,20 patients in ICU of Shaanxi ProvincialPeople's Hospital were taken into group.The samples of sputum and surroundingenvironment samples were cultured.The homology of Acinetobacter baumannii was analyzed by MALDI-Biotyper software,antimicrobial susceptibility test was analyzed by K-B.Results 27 strains of Acinetobacter baumannii were detected,mainly comes from sputum,hands of medical staffs and the environment,homology analysis results showed that the 27 strains of Acinetobacter baumannii was divided into two clusters(Ⅰtype 11 strains,Ⅱ type 16strains),most of Acinetobacter baumannii were multi-resistant bacteria,except for the polymyxin B,minocycline and SCF.Conclusion The ways of transmission of Acinetobacter baumanii in ICU were by medicalpersonnel hand,pollution of the medical equipment and so on,strengthening thedisinfection and reasonable application of antimicrobial agents were taken advantageous for the prevention and control of acinetobacter baumannii infection andtransmission.

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备注/Memo

备注/Memo:
基金项目:2013省科技研究发展(攻关)计划项目《鲍曼不动杆菌在ICU病房传播的前瞻性研究》(2013K12-15-02)。 作者简介:归巧娣(1978-),女,硕士研究生,副主任医师,主要从事临床微生物和细菌耐药研究,E-mail:gqd1212@126.com。 通讯作者:刘文康(1972-),男,副研究员,主要从事感染性疾病诊断和治疗,E-mail:lwk2001@263.net。
更新日期/Last Update: 2017-12-26