[1]施瑞洁,闫福堂,杨 娜,等.血清脂蛋白(a) 水平与胆囊结石并发胆囊炎的相关性研究[J].现代检验医学杂志,2020,35(03):78-80.[doi:10.3969/j.issn.1671-7414.2020.03.019]
 SHI Rui-jie,YAN Fu-tang,YANG Na,et al.Relationship between Serum Lipoprotein (a) Level and Gallstone Complicated by Cholecystitis[J].Journal of Modern Laboratory Medicine,2020,35(03):78-80.[doi:10.3969/j.issn.1671-7414.2020.03.019]
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血清脂蛋白(a) 水平与胆囊结石并发胆囊炎的相关性研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年03期
页码:
78-80
栏目:
论著
出版日期:
2020-07-20

文章信息/Info

Title:
Relationship between Serum Lipoprotein (a) Level and Gallstone Complicated by Cholecystitis
文章编号:
1671-7414(2020)03-078-03
作者:
施瑞洁闫福堂杨 娜苍金荣刘文康迟 洁袁 军
(陕西省人民医院检验科,西安 710068)
Author(s):
SHI Rui-jie YAN Fu-tang YANG Na CANG Jing-rong LIU Wen-kang CHI JieYUAN Jun
(Department of Clinical Laboratory, Shaanxi Provincial People’s Hospital, Xi’an 710068, China)
关键词:
脂蛋白(a)单纯胆囊炎 胆囊结石伴胆囊炎
分类号:
R575.6;R446.112
DOI:
10.3969/j.issn.1671-7414.2020.03.019
摘要:
目的 探讨血清脂蛋白(a) [lipoprotein(a), LP(a)] 在胆囊结石伴胆囊炎疾病中的临床意义。方法 收集2017 年3 月~2018 年9 月临床确诊为胆囊结石伴胆囊炎患者126 例和92 例胆囊炎患者的血清标本,以陕西省人民医院 健康体检中心的147 例健康体检者的血清标本作为对照组, 采用免疫透射比浊法并使用日立7170 全自动生化分析仪 检测受检者血清Lp(a) 水平。结果 胆囊结石伴胆囊炎患者组、单纯胆囊炎患者组和健康对照组血清中Lp(a) 分别为 369.2±258.5,168.6±110.3 和165.9±135.8 mg/L,胆囊结石伴胆囊炎患者组Lp(a) 水平均明显高于单纯胆囊炎患者 组和健康对照组(t=6.391,6.100, 均P<0.01),而单纯胆囊炎患者组与健康对照组之间血清Lp(a) 水平差异无统计学 意义(t=0.261, P>0.05)。各实验组中男性受检者和女性受检者的血清Lp(a) 水平的差异均无统计学意义(t=0.100 6, P>0.05);单纯胆囊炎男性患者和女性患者血清Lp(a) 水平与健康对照受检者的差异均无统计学意义(t=0.132 1,P>0.05), 但是胆囊结石伴胆囊炎男性和女性患者血清Lp(a) 水平均明显高于单纯胆囊炎患者组和健康对照组(t=6.100~6.391, P<0.01)。结论 相比单纯胆囊炎患者,胆囊结石伴胆囊炎患者血清Lp(a) 水平会升高,Lp(a) 对临床诊断胆囊结石伴 胆囊炎有指导作用。
Abstract:
Objective To explore the clinical significance of lipoprotein(a)[Lp(a)] in gallstone complicated by cholecystitis. Methods The serum specimens were collected from 126 cases of patients diagnosed as gallstone complicated by cholecystitis, 92 ones diagnosed as cholecystitis and 147 ones as control group from physical examination center of Shaanxi Province People’s Hospital from March 2017 to August 2018. The serum Lp(a) concentration was detected on the principle of transmitted turbidimetry by Hitachi 7170 Automatic Biochemical Analyzer. Results The means of serum Lp(a) concentration in gallstone complicated by cholecystitis group, cholecystitis one and healthy control one were 369.2±258.5, 168.6±110.3 and 165.9±135.8mg/L, respectively. The mean of serum Lp(a) concentration in gallstone complicated by cholecystitis group was higher than that in cholecystitis one and healthy control one, respectively(t=6.100, 6.391, P<0.01), but there was no statistical difference for serum Lp(a) concentration between cholecystitis group and healthy control one (t=0.261, P>0.05). The serum Lp(a) concentration in male examinees had no statistical difference from that in female ones in all groups, respectively( t=0.100 6, P>0.05).The serum Lp(a) concentration of males in cholecystitis group had no statistical difference from that of females, so did in healthy control group (t=0.132 1,P>0.05), but the mean of serum Lp(a) concentration of males in gallstone complicated by cholecystitis group was respectively higher than that of males in cholecystitis one and healthy control one, so was that of females(t=6.100~ 6.391, P<0.01). Conclusion The serum Lp(a) level increased in patients with gallstone complicated by cholecystitis compared with that in those with cholecystitis and it may be helpful to diagnose gallstone complicated by cholecystitis by mean of serum Lp(a) concentration.

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备注/Memo

备注/Memo:
收稿日期:2019-11-26 修回日期:2020-01-02基金项目:国家高技术研究发展计划(863 计划)项目(2014AA022304)。 作者简介:施瑞洁(1971-)女,本科,主管检验技师,研究方向:临床生化检验技术, E-mail: xasrj001@163.com。 通讯作者:刘文康(1972-)男,博士,副研究员,研究方向:临床生化、免疫检验及相关研究,E-mail: lwk2001@263.net
更新日期/Last Update: 2020-07-20