[1]吴汝香,黄林娟,林　珊,等.福州地区 0~3岁健康儿童外周血红细胞膜六项脂肪酸指标参考区间调查[J].现代检验医学杂志,2021,36(01):96-99.[doi:10.3969/j.issn.1671-7414.2021.01.024]
　WU Ru-xiang,HUANG Lin-juan,LIN Shan,et al.Investigation on Reference Intervals of Sixfatty Acids Indexes of Peripheral Blood Erythrocyte Membrane in Healthy Children Aged 0~3 Years in Fuzhou[J].Journal of Modern Laboratory Medicine,2021,36(01):96-99.[doi:10.3969/j.issn.1671-7414.2021.01.024]
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福州地区 0~3岁健康儿童外周血红细胞膜六项脂肪酸指标参考区间调查()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年01期
页码:
96-99
栏目:
研究简报 实验技术
出版日期:
2021-02-05

文章信息/Info

Title:
Investigation on Reference Intervals of Sixfatty Acids Indexes of Peripheral Blood Erythrocyte Membrane in Healthy Children Aged 0~3 Years in Fuzhou
文章编号:
1671-7414（2021）01-096-04
作者:
吴汝香; 黄林娟; 林　珊; 等
(福建医科大学附属福州儿童医院，福州 350005)
Author(s):
WU Ru-xiang; HUANG Lin-juan; LIN Shan; ZHANG Zhong-long; LIN Xiang-quan
（Fuzhou Children’s Hospital Affiliated to Fujian Medical University，Fuzhou 350005，China）
关键词:
红细胞膜脂肪酸; omega-6; omega-3; 单不饱和脂肪酸; 饱和脂肪酸; 参考区间
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2021.01.024
文献标志码:
A
摘要:
目的　对福州地区 0～ 3岁健康儿童外周血红细胞膜中脂肪酸含量 6项指标的参考区间进行调查。方法　选取 2019年 3月～ 2020年 2月来福州儿童医院体检的 0~3岁健康儿童 60例，分别检测 omega-6多不饱和脂肪酸（ PUFA）总量（简称 omega-6）（包括亚油酸、γ -亚麻酸、二十碳二烯酸、二十碳三烯酸、花生四烯酸和二十二碳四烯酸）， omega-3 PUFA总量（简称 omega-3）（包括 α -亚麻酸、二十碳五烯酸、二十二碳五烯酸和二十二碳六烯酸），单不饱和脂肪酸（ MUFA）总量（包括十六碳一烯酸、十八碳一烯酸、二十碳一烯酸和二十四一烯酸），饱和脂肪酸（ SFA）总量（包括十四烷酸、十六烷酸、十八烷酸、二十烷酸、二十二烷酸和二十四烷酸）， omega-6/omega-3比值和 omega-3指数（即二十碳五烯酸与二十二碳六烯酸总和）共 6项目，含量以百分比（ %）为单位，用于初步调查生物参考区间，均采用 x±1.96s表示。结果　6项指标不同性别、不同年龄差异均无统计学意义 (P>0.05)，初步建立 omega-6（25.43%~34.09%），omega-3（7.03%~16.68%），MUFA(14.02%~18.70%)，SFA（38.95%~46.35%），omega-6/omega-3（1.26~4.61）和 omega-3指数（ 4.62%~13.08%）六项指标参考区间。结论　种族、地域、性别、年龄及饮食结构的差异会影响六项目的参考区间，其不仅客观反映了人体内脂肪酸的分布状况，而且为 0~3岁健康儿童临床检测的结果提供参照；并为儿童补充 omega-3 PUFA提供科学依据，更为进一步建立中国健康人群 PUFA的参考区间打下基础。

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备注/Memo

备注/Memo:
作者简介：吴汝香（1980-），女，副主任检验技师，研究方向：生化、免疫， E-mail：41048382@qq.com。
通讯作者：林祥泉，副主任检验技师，E-mail：Lxq97@126.com。
更新日期/Last Update: 2021-02-05