[1]闫海燕,杨云华,杨云秀,等.ARDS患者肺泡动脉氧分压差与死腔分数检测在病情判断和短期预后评估中的应用价值[J].现代检验医学杂志,2021,36(02):132-135.[doi:doi:10.3969/j.issn.1671-7414.2021.02.031]
　YAN Hai-yan,YANG Yun-hua,YANG Yun-xiu,et al.Application Value of Difference of Alveolar Arterial Oxygen Partial Pressure and Dead Volume Ratio in the ARDS Patients to Judge Disease Condition and Short-Term Prognosis Assessment[J].Journal of Modern Laboratory Medicine,2021,36(02):132-135.[doi:doi:10.3969/j.issn.1671-7414.2021.02.031]
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ARDS患者肺泡动脉氧分压差与死腔分数检测在病情判断和短期预后评估中的应用价值()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年02期
页码:
132-135
栏目:
检验与临床
出版日期:
2021-04-30

文章信息/Info

Title:
Application Value of Difference of Alveolar Arterial Oxygen Partial Pressure and Dead Volume Ratio in the ARDS Patients to Judge Disease Condition and Short-Term Prognosis Assessment
文章编号:
1671-7414（2021）02-132-05
作者:
闫海燕; 杨云华; 杨云秀; 等
（1.咸阳市第一人民医院呼吸与危重症医学科，陕西咸阳 712000；2.西安北车医院内科，西安 710085；3.陕西唐华四棉医院呼吸科，西安 710038；4.深圳市中医院，广东深圳 518033）
Author(s):
YAN Hai-yan;  YANG Yun-hua;  YANG Yun-xiu;  et al
(1.Pulmonary and Critical Care Medicine, the First People’s Hospital of Xianyang, Shaanxi Xianyang 712000, China;2. Department of Medicine, Xi’an Beichang Hospital, Xi’an 710085, China;3.Department of Respiration,Shaanxi Tanghua Simian Hospital, Xi’an 710038, China;4. Shenzhen Hospital of Traditional Chinese Medicine, Guangdong Shenzhen 518033, China)
关键词:
肺泡动脉氧分压差; 死腔分数; 急性呼吸窘迫综合征
分类号:
R563.8；R446.112
DOI:
doi:10.3969/j.issn.1671-7414.2021.02.031
文献标志码:
A
摘要:
目的　研究急性呼吸窘迫综合征（ARDS）患者肺泡动脉氧分压差[P(A-a)O2]和死腔分数（VD/VT）在病情判断和短期预后评估中的应用价值。方法　收集2018年7月～2020年7月咸阳市第一人民医院84例急诊ARDS患者作为研究对象，根据ARDS病情将84例患者分为A组（轻度，28例），B组（中度，30例）及C组（重度，26例）。比较三组急诊患者入院后P[(A-a)O2]和VD/VT水平，记录28天病死率，分析[P(A-a)O2]和VD/VT判断急诊ARDS病情程度和死亡风险的价值。结果　A，B，C三组VD/VT水平依次为0.49±0.07，0.54±0.10，0.59±0.08；P（A-a）O2（mmHg）水平依次为160.67±56.32，234.45±80.98，348.29±135.74。C组患者VD/VT和P(A-a)O2水平显著高于A,B两组，B组VD/VT和P(A-a)O2水平显著高于A组，差异均有统计学意义（F=9.381，26.389，均P<0.05）。84例患者中死亡28例，28天病死率为33.33%。P(A-a)O2判断重度ARDS的AUC为0.794（SE=0.071，95%=0.655～0.934），敏感度和特异度分别为0.769和0.690。入院4天时VD/VT预测ARDS死亡的AUC为0.824（SE=0.066，95%=0.694～0.953），敏感度和特异度分别为0.857和0.607。结论　P(A-a)O2, VD/VT与急诊ARDS病情程度和28天病死率相关，P(A-a)O2有助于判断病情程度，而入院4天时VD/VT水平对预测ARDS死亡准确性较高。

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备注/Memo

备注/Memo:
作者简介：闫海燕（1983-），女，本科，主治医师，研究方向：呼吸重症、肺心病、肺部感染，E-mail：xianyyanhaiy@163.com。
通讯作者：宋晓伟（1987-），男，本科，研究方向：气道肿瘤，E-mail：415510359@qq.com。
更新日期/Last Update: 2021-04-10