[1]张 睿,叶阿里,孔令君,等.临床患者三种性传播疾病分子生物学检测分析[J].现代检验医学杂志,2015,30(03):107-110.[doi:10.3969/j.issn.1671-7414.2015.03.031]
　ZHANG Rui,YE A-li,KONG Ling-jun,et al.Clinical Molecular Biology Analysis of Three Kinds of Sexually Transmitted Diseases in Patients[J].Journal of Modern Laboratory Medicine,2015,30(03):107-110.[doi:10.3969/j.issn.1671-7414.2015.03.031]
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临床患者三种性传播疾病分子生物学检测分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年03期
页码:
107-110
栏目:
论著
出版日期:
2015-06-10

文章信息/Info

Title:
Clinical Molecular Biology Analysis of Three Kinds of Sexually Transmitted Diseases in Patients
文章编号:
1671-7414(2015)03-107-04
作者:
张 睿; 叶阿里; 孔令君; 陈 雨; 窦亚玲; 徐英春
中国医学科学院 北京协和医学院 北京协和医院检验科,北京 100730
Author(s):
ZHANG Rui; YE A-li; KONG Ling-jun; CHEN Yu; DOU Ya-ling; XU Ying-chun
Department of Clinical Laboratory, Peking Union Medical College Hospital,CAMS and PUMC,Beijing 100730,China
关键词:
解脲脲原体;  沙眼衣原体;  淋病奈瑟菌;  RNA;  恒温扩增检测技术
分类号:
R378.16; R374; R392.11
DOI:
10.3969/j.issn.1671-7414.2015.03.031
文献标志码:
A
摘要:
目的 分析就诊于北京协和医院患者沙眼衣原体(chlamydiatrachomatis,CT)、淋病奈瑟菌(neisseria gonorrhoeae,NG)、解脲脲原体(ureaplasmaurealyticum,UU)三种性传播疾病的检出情况以及相关因素。方法 收集2013年1月1日～2014年12月31日两年间样本,采用实时荧光核酸恒温扩增检测技术(simultaneous amplification and testing,SAT)进行CT-RNA,NG-RNA和UU-RNA的检测并分析。结果 6 262例送检样本中,2013年2 412例,2014年3 850例。CT-RNA,NG-RNA和UU-RNA的阳性率:2013年分别为:7.29%,3.44%和38.21%; 2014年分别为8.17%,4.15%和45.71%,三种病原体阳性率,2014年均高于2013年,其中UU-RNA的阳性率在两年间的差异具有统计学意义(χ2=12.66,P＜0.01)。两年间的CT-RNA,NG-RNA,UU-RNA的总阳性率分别为8.15%,3.89%,42.77%; UU-RNA在女性当中的阳性率为61.05%,远高于男性的阳性率24.50%,其差异具有统计学意义(χ2=316.13,P＜0.01)。CT-RNA,NG-RNA,UU-RNA阳性患者最多见于21～30岁; UU-RNA在宫颈拭子样本中检出率最高。结论 在这三种性传播疾病中UU感染率增高的趋势最为明显; CT和NG较易感染男性,UU则易感染女性; CT,NG,UU病原体在青年中的感染率最高。
Abstract:
Objective To analysis the related factors and the morbidity of patients with Chlamydia trachomatis(CT), Neisseria gonorrhea(NG), Ureaplasma urealyticum(UU)in Beijing Union Medical College Hospital.Methods Simultaneous Amplification and Testing(SAT)was usedto detect CT-RNA,NG-RNA,UU-RNA of patients from January of 2013 to Decemberof 2014.Results There were 6 262 cases in all and 2 412cases in 2013,and 3 850 cases in 2014.The positive rate of CT-RNA,NG-RNA and UU-RNA were 7.29%,3.44% and 38.21% in 2013.The positive rate of CT-RNA,NG-RNA and UU-RNA were 8.17%,4.15% and 45.71% in 2014 respectively,which were higher than those of in 2013.There was a significant difference in UU-RNA positive rate between the two years(χ2=12.66,P＜0.01).The positiverate of CT-RNA,NG-RNA and UU-RNA were 8.15%,3.89% and 42.77% respectively in two years.The positive rate of UU-RNA in women's(61.05%)was significantly higherthan the men's(24.50%)(χ2=316.13,P＜0.01).Most of the people withCT-RNA,NG-RNA and UU-RNA-positive were between 21 to 30 years old.The highest detection positive rate was in cervical swabs samples of UU-RNA.Conclusion There was a significantly increasing trend of the infection with UU.Male were more susceptible to CT and NG.However,female were moresusceptible to UU.There was the highest infection rate in youth(21～30 years)with CT,NG and UU.

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备注/Memo

备注/Memo:
作者简介:张 睿(1983-),女,硕士研究生,现任实习研究员,研究方向:感染与肿瘤相关分子生物学检测和诊断,E-mail: zhangrui_pumc@163.com。
通讯作者:窦亚玲,Tel:010-69159702,E-mail:douyling@163.com。
更新日期/Last Update: 2015-06-10