[1]辛毅娟a,史皆然b,杨柳a,等.ICUs分离的三种重要病原菌的耐药特性与基因型分析[J].现代检验医学杂志,2015,30(05):24-27.[doi:10.3969/j.issn.1671-7414.2015.05.008]
　XIN Yi-juana,SHI Jie-ranb,YANG Liua,et al.Drug Resistance and Homological Analysis of Important Clinical Bacterial Pathogens[J].Journal of Modern Laboratory Medicine,2015,30(05):24-27.[doi:10.3969/j.issn.1671-7414.2015.05.008]
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ICUs分离的三种重要病原菌的耐药特性与基因型分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年05期
页码:
24-27
栏目:
论著
出版日期:
2015-12-10

文章信息/Info

Title:
Drug Resistance and Homological Analysis of Important Clinical Bacterial Pathogens
作者:
辛毅娟a; 史皆然b; 杨柳a; 杨玉琪a; 徐修礼a; 周珊a; 郝晓柯a; 马越云a
第四军医大学西京医院a.检验科；b.感染科，西安710032
Author(s):
XIN Yi-juana; SHI Jie-ranb; YANG Liua; YANG Yu-qia; XU Xiu-lia;  ZHOU Shana; HAO Xiao-kea; MA Yue-yuea
a.Department of Clinical Laboratories；b.Department of Infectious Disease，Xijing Hospital，Xi’an 710032，China
关键词:
病原菌; 耐药性; 基因型
分类号:
R378；R446.5
DOI:
10.3969/j.issn.1671-7414.2015.05.008
文献标志码:
A
摘要:
目的了解西京医院重症监护室分离的3种重要感染病原菌的耐药性和同源性。方法于2013年11月～2014年3月收集西京医院重症监护室分离到的15株金黄色葡萄球菌，24株鲍曼不动杆菌和22株铜绿假单胞菌，应用VITEK-32微生物鉴定药敏分析系统对感染病原菌进行菌种鉴定和药物敏感性试验；应用Diversilab基因分型系统对感染病原菌进行同源性分析。结果15株金黄色葡萄球菌分为A1，A2，B，C等4型；24株鲍曼不动杆菌分为A和C型两型。22株铜绿假单胞菌分为A1，A2，A3，A4，A5，B，C型等7型。相同菌株不同基因型之间存在不同的耐药性；来自不同区域的同型菌株存在不同的耐药性。结论同源区域明显相关，综合分析有助于了解院内感染病原菌的流行趋势和感控效果。
Abstract:
ObjectiveTo investigate the antimicrobial resistance and homology of the 3 clinical bacterial pathogens from the intensive care units of Xijing Hospital．MethodsCollected the clinical infectious pathogens，including 15 Staphylococcus aureus，24 Bauman acinetobacter and 22 Pseudomonas aeruginosa from November 2013 to March 2014．Pathogens were identified with VITEK-32 automatic microorganism analyzer．At the same time，the drug susceptibility testing was performed．The homology was identified by using automated DiversiLab System DNA fingerprinting．Results15 strains of Staphylococcus aureus could be divided into A1，A2，B and C genotypes．24 strains of Bauman acinetobacter could be divided into A and C genotypes．22 strains of Pseudomonas aeruginosa could be divided into A1，A2，A3，A4，A5，B，and C genotypes．There was different resistance among the same strains of different genotypes，and the same genotype strains from different areas had different drug resistance．ConclusionThere was a high relationship between the drug resistance，genotype and the area it was from．It was suggested that combined analysis these 3 factors might be helpful for full understand the control of the hospital infection．

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备注/Memo

备注/Memo:
作者简介：辛毅娟(1985-)，女，医学硕士，检验技师，从事病原微生物的流行病学及致病机制的研究，Tel：029-84771034，E-mail：xy850510@126.com。 通讯作者：马越云，博士，副教授，博士研究生导师，Tel： 029-84775959，E-mail：cmbmayy@fmmu.edu.cn。
更新日期/Last Update: 1900-01-01