[1]王建彬,李雪萍,曾维英,等.性病门诊尖锐湿疣患者指尖HPV感染情况调查[J].现代检验医学杂志,2018,33(03):148-150.[doi:10.3969/j.issn.1671-7414.2018.03.038]
　WANG Jian-bin,LI Xue-ping,ZENG Wei-ying,et al.Investigation of Fingertip HPV Infection in Patients with Condylomata Acuminate in STD Clinic[J].Journal of Modern Laboratory Medicine,2018,33(03):148-150.[doi:10.3969/j.issn.1671-7414.2018.03.038]
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性病门诊尖锐湿疣患者指尖HPV感染情况调查()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年03期
页码:
148-150
栏目:
检验与临床
出版日期:
2018-07-17

文章信息/Info

Title:
Investigation of Fingertip HPV Infection in Patients with Condylomata Acuminate in STD Clinic
文章编号:
1671-7414(2018)03-148-03
作者:
王建彬1; 李雪萍1; 曾维英2; 程 庆2; 赖嘉希2; 陈惠茹2; 柯吴坚2
1.汕头市皮肤性病防治院,广东汕头 515041; 2.南方医科大学皮肤病医院,广州 510009
Author(s):
WANG Jian-bin1; LI Xue-ping1; ZENG Wei-ying2; CHENG Qing2; LAI Jia-xi2; CHEN Hui-ru2;  KE Wu-jian2
1.Shantou Hospital of Skin Disease Prevention and Cure,Guangdong Shantou 515041,China; 2.Dermatology Hospital of Southern Medical University,Guangzhou 510009,China
关键词:
尖锐湿疣;  指尖;  人乳头瘤病毒感染
分类号:
R752.53; R446.5
DOI:
10.3969/j.issn.1671-7414.2018.03.038
文献标志码:
A
摘要:
目的 明确尖锐湿疣(CA)患者手指尖人乳头瘤病毒(HPV)感染情况。方法 招募性病门诊确诊为CA的患者119例,采用PCR方法检测其指尖HPV感染情况。CA患者指尖HPV感染情况与性别比较采用卡方检验,与年龄、病程比较采用两个独立样本t检验。结果 119例指尖样本有31例HPV DNA阳性,阳性率为26.1%。男性CA患者中指尖HPV感染率为29.8%(17/57),高于女性的22.6%(14/62),差异无统计学意义(χ2=0.808,P=0.368)。指尖HPV阳性者平均年龄为31.74±6.79岁,低于阴性者的33.98±10.36岁,差异无统计学意义(t=1.119,P=0.266)。指尖HPV阳性者平均病程为5.74±4.40月,高于阴性者的4.41±2.12月,差异有统计学意义(t=2.213,P=0.029)。结论 CA患者指尖HPV感染率高,提示HPV可能经手间接感染。性别和年龄与指尖HPV感染无关,而与病程长短有关,病程越长感染率越高。
Abstract:
Abstract:Objective To investigate the fingertip human papillomavirus(HPV)infection in condylomata acuminate(CA)patients of sexuallytransmitted disease(STD)clinic.Methods 119 CA patientsin STD clinic were recruited.The PCR method was used to detect HPV infection in their fingertips.The chi-square test was used to compare the fingertip HPV infection with gender.The two independent samples t-test was used to compare the fingertip HPV infection with age and the course of disease.Results 31 CA patients' fingertip were infected with HPV DNA,and theinfection rate was 26.1%.The fingertip HPV infection rate in male CA patientswas 29.8%(17/57),which higher than in women of 22.6%(14/62),and the difference was not significant(χ2=0.808,P=0.368).The average age in the fingertip HPV positive patients were 31.74±6.79 years,which less than the negative patients of 33.98±10.36 years,and the difference was not significant(t=1.119,P=0.266).The average course of disease in the fingertip HPV positive patients were 5.74±4.40 months,which higher than the negative patientsof 4.41±2.12 months,and the difference was significant(t=2.213,P=0.029).Conclusion The fingertip HPV infection rate was highin CA patients,suggesting that HPV infection may be transmitted by hands.Gender and age fingertip HPV infection had nothing to do with the duration of disease-related,the longer the course of disease,the higher the fingertip HPV infection rate in CA patients.

参考文献/References:

[1] Rosenberg K,Mechcatie E.HPV vaccination and sexual behaviors inadolescents and young women[J].Am J Nurs,2018,118(4):69.
[2] Napolitano F,Navaro M,Vezzosi L,et al.Primary care pediatricians' attitudes and practice towards HPV vaccination: A nationwide survey in Italy[J].PLoS One,2018,13(3):e0194920.
[3] 赖嘉希,柯吴坚,刘 晗.人乳头状瘤病毒非性行为传播途径的研究现状[J].护理研究,2017,31(19):2319-2320. Lai JX,Ke WJ,Liu H.Research status quo of non-sexual transmission of human papilomaviruses[J].Nursing Research of China,2017,31(19):2319-2320.
[4] Hernandez BY,Wilkens LR,Zhu X,et al.Transmission of human papillomavirus in heterosexual couples[J].Emerg Infect Dis,2008,14(6):888-894.
[5] Winer RL,Hughes JP,Feng Q,et al.Detection of genital HPV types in fingertip samples from newly sexually active female university students[J].Cancer Epidemiol Biomarkers Prev,2010,19(7):1682-1685.
[6] Winer RL,Lee SK,Hughes JP,et al.Genital human papillomavirus infection:incidence and risk factors in a cohort of female university students[J].AmJ Epidemiol,2003,157(3):218-226.
[7] Scheller NM,Pasternak B,M(¨overo)lgaard-Nielsen D,et al.Quadrivalent HPV vaccination and the risk of adverse pregnancy outcomes[J].N Engl J Med,2017,376(13):1223-1233.
[8] Schuster M.Human papillomavirus vaccines:WHO position paper,October 2014-Recommendations[J].Vaccine,2015,33(36):4383-4384.
[9] Kulhan M,Kulhan NG,Seven Y,et al.Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women[J].Contemp Oncol(Pozn,Poland),2017,21(3):218-223.
[10] Han JJ,Beltran TH,Song JW,et al.Prevalence of genital humanpapillomavirus infection and human papillomavirus vaccination rates among US adult men:National health and nutrition examination survey(NHANES)2013～2014[J].JAMA Oncol,2017,3(6):810-816.
[11] 杜伟平,米思蓉,王 丽,等.延安地区妇女HPV基因分型及临床相关研究[J].现代检验医学杂志,2018,33(1):109-111,114. Du WP,Mi SR,Wang L,et al.HPV genotyping and clinical studies of women in Yan'an area[J].Journal of Modern Laboratory Medicine,2018,33(1):109-111,114.
[12] 原 荣,李 军,南 星,等.陕西省宝鸡和咸阳两地妇女HPV感染现状和类型分析[J].现代检验医学杂志,2017,32(6):145-146,150. Yuan R,Li J,Nan X,et al.HPV prevalence and subtypes analysis of womenin Baoji and Xianyang area of Shaanxi province[J].Journal of Modern Laboratory Medicine,2017,32(6):145-146,150.

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备注/Memo

备注/Memo:
基金项目:广东省医学科学技术研究基金项目(A2018248,A2017224)。 作者简介:王建彬(1982-),男,医学学士,主治医师,研究方向:性传播疾病,E-mail:247741373@qq.com。 通讯作者:柯吴坚,男,医学博士,研究方向:性传播疾病,E-mail:kewujianstauch@163.com。
更新日期/Last Update: 2018-04-16