[1]钟 堃,王 薇,何法霖,等.全国231家临床实验室23项干化学 与湿化学检验项目参考区间的比较和分析[J].现代检验医学杂志,2015,30(01):145-148.[doi:10.3969/j.issn.1671-7414.2015.01.044]
　ZHONG Kun,WANG Wei,HE Fa-lin,et al.Comparison of the Reference Intervals of 23 Analytes between Wet Chemistry and Dry Chemistry in 231 Clinical Laboratories in China[J].Journal of Modern Laboratory Medicine,2015,30(01):145-148.[doi:10.3969/j.issn.1671-7414.2015.01.044]
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全国231家临床实验室23项干化学 与湿化学检验项目参考区间的比较和分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年01期
页码:
145-148
栏目:
质量控制·实验室管理
出版日期:
2015-01-30

文章信息/Info

Title:
Comparison of the Reference Intervals of 23 Analytes between Wet Chemistry and Dry Chemistry in 231 Clinical Laboratories in China
文章编号:
1671-7414(2015)01-145-04
作者:
钟 堃; 王 薇; 何法霖; 王治国
北京医院 卫生部临床检验中心,北京 100730
Author(s):
ZHONG Kun; WANG Wei; HE Fa-lin; WANG Zhi-guo
Beijing Hospital,National Center for Clinical Laboratories,Beijing 100730,China
关键词:
干化学;  湿化学;  参考区间;  配对t检验;  中位数检验
分类号:
R446
DOI:
10.3969/j.issn.1671-7414.2015.01.044
文献标志码:
A
摘要:
目的 该研究拟对目前中国医院检验科干化学检验项目的参考区间与对应湿化学的参考区间进行比较,了解医院检验科干、湿化学检验项目参考区间的差异。方法 采用基于Web方式的室间质量评价(EQA)软件系统,收集参加2014年全国干化学和常规化学(湿化学)参考区间调查的实验室所上报的数据,利用配对t检验和中位数Yates'卡方检验进行统计分析,以确定在同一医疗机构内干化学和湿化学项目的参考区间,以及上下限的中位数之间是否存在差异。结果 231家临床实验室回报了23项干、湿化学检验项目。其中69.6%(32/46)的干、湿化学检验项目参考区间上下限配对比较结果差异存在统计学显著性意义。80.4%(37/46)的干、湿化学检验项目参考区间上下限中位数存在位置与分布的显著性统计学差异。结论 目前中国同一医疗机构干化学与湿化学检验项目参考区间存在一定差异,参考区间上下限的分布和中位数的位置不同,建议建立中国人群干化学检验项目的参考区间。
Abstract:
Objective To compare the current application status of reference intervals in dry chemistry to the reference intervals of anlytes of wet chemistry in the same hospital.Methods By using web-based external quality assessment(EQA)software system,collecting thesubmitted data from the laboratories which attended national reference intervalsinvestigation of reference intervals of analytes in dry chemistry and wet chemistry,using professional statistical software for analyzing the data,including paired-samples t test and Yates' Chi-square test.Results231 laboratories submitted their investigation results including thereference intervals of 23 analytes of dry and wet chemistry.69.6%(32/46)of reference intervals of analytes in dry chemistry have significant statistical differences compared with the wet chemistry in paired-samples t tests.80.4%(37/46)of medians of reference intervals of analytes in dry chemistry had significant statistical differences in locations and distributions compared with medians of reference intervals of wet chemistry in the same institute.Conclusion The reference intervals of analytes of dry chemistry havedifferences compared with the wet chemistry in the same hospital.The medians ofreference interval's lower and higher limits of dry and wet chemistry have difference in locations and distributions.Proposed to create our own reference intervals of dry chemistry in China.

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备注/Memo

备注/Memo:

作者简介:钟 堃(1984-),男,硕士,助理研究员,主要从事临床实验室管理工作。
通讯作者:王治国,Tel:010-58115054,E-mail:zgwang@nccl.org.cn。
更新日期/Last Update: 2015-01-30