[1]王洋一,胡宏章.在不同性别及年龄间糖化血红蛋白水平差异分析[J].现代检验医学杂志,2017,32(02):123-125,130.[doi:10.3969/j.issn.1671-7414.2017.02.034]
 WANG Yang-yi,HU Hong-zhang.Differential Analysis of Glycosylated Hemoglobin in Different Sex and Age[J].Journal of Modern Laboratory Medicine,2017,32(02):123-125,130.[doi:10.3969/j.issn.1671-7414.2017.02.034]
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在不同性别及年龄间糖化血红蛋白水平差异分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年02期
页码:
123-125,130
栏目:
研究简报·实验技术
出版日期:
2017-03-25

文章信息/Info

Title:
Differential Analysis of Glycosylated Hemoglobin in Different Sex and Age
文章编号:
1671-7414(2017)02-123-04
作者:
王洋一胡宏章
四川大学华西医院实验医学科,成都610041
Author(s):
WANG Yang-yiHU Hong-zhang
Department of Laboratory Medicine, West Hospital of Sichuan University,Chengdu 610041,China
关键词:
糖尿病 糖化血红蛋白 年龄 性别
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2017.02.034
文献标志码:
A
摘要:
目的 研究糖化血红蛋白在不同年龄、性别间的水平差异,为糖尿病预防、早期的诊治提供参考依据。方法 选择9 094例门诊及住院人群资料,按照不同年龄组分为≤30岁(464例),31~40岁(715例),41~50岁(1 939例),51~60岁(1 754例),61~70(2 290例),71~80岁(1 497例)和>80岁(435例),分别对7组人群抽取静脉血检测并比对糖化血红蛋白,分析糖化血红蛋白在不同年龄段和性别间的水平差异。结果 全体受试人群糖化血红蛋白水平为:≤30岁(5.42±0.841)%,31~40岁(5.61±1.088)%,41~50岁(5.93±1.264)%,51~60岁(6.18±1.298)%,61~70(6.21±1.232)%,71~80岁(6.29±1.270)%和>80岁(6.35±1.314)%,均随年龄的增加而呈增高的趋势,差异具有统计学意义(F=63.81,P<0.001); 70岁以内糖化血红蛋白水平男性高于女性,18~50岁三个年龄组HbA1c水平男性与女性比较差异有统计学意义(P<0.05)。结论 糖化血红蛋白水平与年龄、性别存在一定的相关性,且随着年龄增长而增高,适合应用于体检筛查,尤其适合中老年人群的糖化血红蛋白水平的监测。
Abstract:
Objective To study the glycosylated hemoglobinin the level difference between different age,sex and provide a reference for the prevention,early diagnosis and treatment of diabetes.Methods 9 094 cases in clinic of population data were included in this study,according to the different age groups were divided into 30 years old or less group(464 cases),30~40 years old group(715 cases),41~50 years old group(1 939cases),51~60 years old group(1 754 cases),61~70(2 290 cases),71~80 years old group(1 497 cases)and >80 years old group(435 cases),7 groups of extraction of venous blood tested glycated hemoglobin and compared,analysis of glycosylated hemoglobin levels between different age groups and different gender differences.Results All subjects crowd glycosylated hemoglobin levels were ≤30 years old group(5.42±0.841)%,31~40 years old group(5.61±+1.088)%,41~50 years old group(5.93±1.264)%,51~60 years old group(6.18±1.298)%,61~70 years old group(6.21±1.232)%,71~80 years old group(6.29±1.270)%,>80 years old group(6.35±1.314)% all were a trend of increase with the increase of age,the difference was statistically significant(F=63.81,P<0.001).The level of glycosylated hemoglobin was significantly higher in male than in female within 70 years of age,and there was significant difference in HbA1c level between 18~50 years old(P<0.05).Conclusion There was a correlation between the level of glycosylated hemoglobin with different age,sex and increasing with age.It is suitable for physical examination and screening,and in particular,monitoring of glycosylated hemoglobin levels in middle aged and old age.

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备注/Memo

备注/Memo:

作者简介:王洋一(1987-),男,本科,检验技师,从事生化检验,Tel:028-62539087,E-mail:15882204120@163.com。
通讯作者:胡宏章(1972-),男,硕士,主管检验技师,从事血液学检验,Tel:13258295179,E-mail:hhhhzh110@163.com。
更新日期/Last Update: 2017-04-10