[1]田 琼,高田原,谢 航,等.早期带状疱疹、急性胆囊炎、急性心肌梗死患者血细胞计数检测结果比较的临床分析[J].现代检验医学杂志,2017,32(06):139-141,144.[doi:10.3969/j.issn.1671-7414.2017.06.001]
　TIAN Qiong,GAO Tian-yuan,XIE Hang,et al.Blood Routine Analysis of Patients with Herpes Zoster at Early Stage,Acute Cholecystitis and Acute Myocardial Infarction[J].Journal of Modern Laboratory Medicine,2017,32(06):139-141,144.[doi:10.3969/j.issn.1671-7414.2017.06.001]
点击复制

早期带状疱疹、急性胆囊炎、急性心肌梗死患者血细胞计数检测结果比较的临床分析()

《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年06期
页码:
139-141,144
栏目:
研究简报·实验技术
出版日期:
2017-12-25

文章信息/Info

Title:
Blood Routine Analysis of Patients with Herpes Zoster at Early Stage,Acute Cholecystitis and Acute Myocardial Infarction
文章编号:
1671-7414(2017)06-139-04
作者:
田 琼1a,高田原1a,谢 航1b,刘文丽1a,薛娟娟2,张 键1a
1.西安交通大学第一附属医院a.皮肤科; b.结构性心脏病科, 西安 710061; 2.横山县医院皮肤科,陕西榆林 719000
Author(s):
TIAN Qiong1a,GAO Tian-yuan1a,XIE Hang1b,LIU Wen-li1a,XUE Juan-juan2,ZHANG Jian1a
1a.Department of Dermatology; 1b.Department of Structural Cardiology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China; 2.Department of Dermatology,Hengshan Hospital,Shaanxi Yulin 719100,China
关键词:
带状疱疹;  血常规;  鉴别诊断
分类号:
R373.11; R446.111
DOI:
10.3969/j.issn.1671-7414.2017.06.001
文献标志码:
A
摘要:
目的 比较早期带状疱疹、急性胆囊炎和急性心肌梗死患者入院时血细胞计数检测结果的不同,分析不同指标变化在三种疾病鉴别诊断中的价值。方法 按一定的纳入排除标准,选取2013年10月～2017年3月于西安交通大学第一附属医院确诊的带状疱疹患者78例、急性胆囊炎患者59例、急性心肌梗死患者51例,比较其入院血常规检查各指标的结果,分析其受试者工作特征(ROC)曲线,寻找各指标的最佳截断值。结果 早期带状疱疹患者的白细胞计数(WBC)、血小板计数(PLT)、中性粒细胞百分比(NE%)三个指标均低于急性胆囊炎和急性心肌梗死患者(P<0.05); 淋巴细胞百分比(LYM%)和单核细胞百分比(MO%)指标均高于急性胆囊炎和急性心肌梗死患者(P<0.05)。其中做鉴别诊断价值最高的是NE%指标(AUC=0.848,95%CI:0.792～0.905); 特异度最高的指标是LYM%,在最佳截断值19.21%处,特异度可达0.963。结论 血细胞计数检查结果对早期带状疱疹的鉴别诊断具有一定的意义,可降低早期带状疱疹诊断的漏诊率和误诊率。
Abstract:
Abstract:Objective To evaluate the diagnostic value of these alternant indexes by compare the results of routine blood test of early herpes zoster(HZ),acute cholecystitis and acute myocardial infarction patients.Methods According to some inclusion and exclusion criteria,78 HZ patients,59 acute cholecystitis and 51 acute myocardial infarction patients from October 2013 to March 2017 were included.The receiver operator characteristics(ROC)were used to evaluate the diagnostic value of the blood corpuscle indexes.Results White blood cell count(WBC),blood platelet count(PLT)and neutrophilic granulocyte percentage(NE%)of HZ patientswere lower than the acute cholecystitis and acute myocardial infarction patients(P<0.001).Lymphocyte percentage(LYM%)and monocyte percentage(MO%)were higher than the others'.The NE% index had a certain diagnostic value(AUC=0.848,95%CI:0.792～0.905).There was a highest specificity in LYM% index(specificity=0.963).Conclusion There were some clinical significance of routine blood cell count results on the early HZ diagnosis,which can reduce the missed diagnosis and misdiagnosis rate of an early diagnosisherpes zoster.

参考文献/References:

[1] Varghese L,Standaert B,Olivieri A,et al.The temporal impact of aging on the burden of herpes zoster[J].BMC Geriatrics,2017,17(1):30.
[2] 罗志广,黄秀娟,杨国良,等.154例带状疱疹误诊原因分析[J].保健医学研究与实践, 2014,11(3):38-40. Luo ZG,Huang XJ,Yang GL,et al.Analysis on the cause of misdiagnosis in 154 cases of patients with herpes zoster[J].Health Medicine Research and Practice,2014,11(3):38-40.
[3] Kapoor U,Juneja M. Case reports:misdiagnosed herpes zoster[J].Br Dent J,2015,218(9):507.
[4] 郭向阳,严晓华,王 侠.儿童感染性疾病中降钙素原、超敏C-反应蛋白和白细胞联合检测的价值及相关性研究[J].现代检验医学杂志,2014,29(3):56-59. Guo XY,Yan XH,Wang X.Role and correlation of procalcitonin,hypersensitive C-reactive protein and white blood cell count in children infection diseases[J].Journal of Modern Laboratory Medicine,2014,29(3):56-59.
[5] 郭志雄,彭 政,陈 聪.白细胞VCS参数在细菌及病毒感染的鉴别临床应用研究[J].中华医院感染学杂志,2013,23(17):4327-4329. Guo ZX,Peng Z,Chen C.Study of leukocyte VCS parameters in differential diagnosis of bacterial or viral infections[J].Chinese Journal of Nosocomiology,2013,23(17):4327-4329.
[6] 胡道军,郁 淼,张洪磊,等.基于Logistic回归和ROC曲线综合评价IMA,NLR,hs-CRP和CK-MB联合检测对早期急性心肌梗死的诊断价值[J].现代检验医学杂志,2016,31(5):76-80. Hu DJ,Yu M,Zhang HL,et al.Comprehensive evaluation of the diagnostic value of the combined detection of IMA,NLR,hs-CRP and CK-MB for acute myocardial infarction based on ROC curve and Logistic regression analysis[J].Journal of Modern Laboratory Medicine,2016,31(5):76-80.
[7] Garcia-Gonzalez AI,Rosas-Carrasco O.Herpes zoster and post-herpetic neuralgia in the elderly:particularities in prevention,diagnosis,and treatment[J].Gaceta Medica de Mexico,2017,153(1):92-101.
[8] 宋郁河,李淑闽,林 甦,等.水痘患儿血浆C反应蛋白检测及意义[J].现代生物医学进展,2010,10(6):1151-1152. Song YH,Li SM,Lin S,et al.Determination and significance of serum CRP in children with varicella[J].Progress in Modern Biomwdicine,2010,10(6):1151-1152.
[9] Muta Y,Odaka A,Inoue S,et al.Acute acalculous cholecystitis with eosinophilic infiltration[J].Pediatr Int,2015,57(4):788-791.
[10] 白宏宇,叶剑飞,夏洪刚,等.CRP在炎症性急腹症与带状疱疹鉴别诊断中的应用价值[J].当代医学,2013,19(25):21-22. Bai HY,Ye JF,Xia HG,et al.The value of C-reactive protein(CRP)in differential diagnosis between in ammatory acute abdomen and herpes zoster[J].Contemporary Medicine,2013,19(25):21-22.
[11] 朱益佳,宁明哲,杨 平,等.血清炎症性肠病抗体谱的检测对IBD诊断及鉴别诊断的临床价值[J].现代检验医学杂志,2017,32(1):141-143. Zhu YJ,Ning MZ,Yang P,et al.Clinical value of diagnosis and differential diagnosis of detection of serum inflammatory bowel disease antibody spectrumin IBD[J].Journal of Modern Laboratory Medicine,2017,32(1):141-143. 收稿日期:2017-04-13 修回日期:2017-09-25

备注/Memo

备注/Memo:
基金项目:陕西省科技攻关项目,项目编号2014K11-02-03-13。 作者简介:田 琼(1988-),女,硕士研究生,住院医师,研究方向:银屑病,损容性皮肤病,E-mail:tianqiong198805@163.com。 通讯作者:张 键,硕士研究生,主治医师,E-mail:yiiling10@163.com。
更新日期/Last Update: 2017-12-26