[1]于国慧,吕志勇,宋文琪.儿童疑似肺炎支原体感染者血清、支气管灌洗液、胸腔积液、脑脊液MP-Ab-IgM检测的结果分析[J].现代检验医学杂志,2018,33(02):93-96.[doi:10.3969/j.issn.1671-7414.2018.02.001]
　YU Guo-hui,L(¨overU)Zhi-yong,SONG Wen-qi.1671-7414(2018)02-093-04[J].Journal of Modern Laboratory Medicine,2018,33(02):93-96.[doi:10.3969/j.issn.1671-7414.2018.02.001]
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儿童疑似肺炎支原体感染者血清、支气管灌洗液、胸腔积液、脑脊液MP-Ab-IgM检测的结果分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年02期
页码:
93-96
栏目:
论著
出版日期:
2018-04-05

文章信息/Info

Title:
1671-7414(2018)02-093-04
文章编号:
1671-7414(2018)02-093-04
作者:
于国慧; 吕志勇; 宋文琪
首都医科大学附属北京儿童医院,北京 100045
Author(s):
YU Guo-hui; L(¨overU)Zhi-yong; SONG Wen-qi
Beijing Children's Hospital Affiliated to Capital Medical University,Beijing 100045,China
关键词:
肺炎支原体;  儿童;  肺炎支原体肺炎
分类号:
R375.2; R392.11
DOI:
10.3969/j.issn.1671-7414.2018.02.001
文献标志码:
A
摘要:
目的 分析肺炎支原体肺炎(MPP)患儿血清、支气管灌洗液、胸腔积液及脑脊液的肺炎支原体(MP)MP-Ab-IgM检测结果。方法 选取2013年3月～6月在首都医科大学附属北京儿童医院疑似MP感染的278例住院患儿的血清、支气管灌洗液、胸腔积液及脑脊液标本,采用颗粒凝集的方法检测MP-Ab-IgM。结果181例患儿(男孩104例,女孩77例)的不同标本中MP呈阳性反应。278例患儿均进行了血清标本检测,共检出阳性血清标本170例,总检出率为61.2%(170/278),144例同时进行了支气管灌洗液检测,检出阳性62例,检出率为43.1%(62/144); 19例同时进行了胸腔积液标本检测,检出阳性13例,检出率为68.4%(13/19); 15例同时进行了脑脊液标本检测,检出阳性1例,检出率为6.7%(1/15)。各年龄组间检出率分别为:6个月～1岁组29.0%(9/31),～3岁组51.0%(25/49),～5岁组56.1%(23/41),～16岁组79.0%(124/157),6个月～1岁组与其他年龄组比较差异有统计学意义(P<0.05); ～3岁与～5岁组间差异无统计学意义(P>0.05),而与～16岁组间差异有统计学意义(P<0.05)。在6个月～1岁,～3岁,～5岁,～16岁四个年龄组中,同一患儿检测的不同类型MP-Ab-IgM阳性标本,其对应结果为A:血清类(111例)7,21,13和70; B:血清-支气管灌洗液类(45例)0,2,5和38; C:血清+胸腔积液类(7例)0,1,2和4; D:血清+脑脊液(1例)0,0,0和1; E:血清+支气管灌洗液+胸腔积液类(6例)0,0,2和4; F:支气管灌洗液类(11)2,1,1和7。结论 MP感染多种多样,有低龄化趋势,且有逐年增多的趋势。不同年龄组间血清阳性检出率随年龄增长逐渐增加,婴幼儿阳性检出率明显升高,重症患儿多发于年龄较大的患儿。
Abstract:
Abstract:Objective To study the infection of MP-Ab-IgM(MP)in serum,bronchial lavage fluid,pleural effusion and cerebrospinal frompediatric patients with Mycoplasma Pneumoniae Pneumonia(MPP).Methods From March to June 2013,278 cases of patients suspected MP infection in Children's Hospital Affiliated to Capital Medical University were selected and the MP -Ab-IgM of theire serum,bronchial lavage fluid,pleural effusion and cerebrospinal fluid specimens were detected with the method of particle agglutination test.Results 181 cases(104 cases of boys,77 cases of girls)of different specimens in(MP)were positive.All the serum samples,278 cases were detected positive serum specimen of 170 cases,the overall detection rate was 61.2%(170/278),144 cases of bronchial lavage fluid was investigated at the same time,check out the positive 62 cases,and the detection rate was 43.1%(62/144).19 cases for pleural effusion samples at the sametime,checked out the positive 13 cases,and detection rate was 68.4%(13/19).15 cases of cerebrospinal fluid specimens was investigated at the same time,checked out the positive in 1 case,and the detection rate was 6.7%(1/15).Positive rate between different age groups was respectively:6 months～1 year group 29.0%(9/31),～3 year group 51.0%(25/49),～5 year group 56.1%(23/41),～16 year group 79.0%(124/157),6 months～1 year with other age groups was statistically significant difference(P<0.05).In 0.5～1 year,～3 year,～5 year,16 year～four age groups,different types of MP-Ab-IgM positive specimens of the same patients,the corresponding results for A:serum type(111 cases)7,21,13,70.B:serum and bronchoalveolar lavage fluid type(45 cases)0,2,5,38.C:Serum pleural effusion(7 cases)0,1,2,4.D:serum and cerebrospinal fluid(1 cases)0,0,0,1; E:serum and bronchoalveolar lavage fluid and pleural effusiontype(6 cases):0,0,2,4.F:bronchoalveolar lavage fluid type(11)2,1,1,7.Conclusion MP infection varied,have atrend of youngerage,and has a tendency to increase year by year,and the patient's infection rates have different characteristics.Positive serum of different age groups wasgradually increased with age,infants and young children positive detection rateincreased significantlychildren with severe multiple in older children.

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备注/Memo

备注/Memo:
作者简介:于国慧(1962-),女,大专,主管检验师,从事血清免疫学及临床检验学,E-mail:ygh0608@hotmail.com。 通讯作者:宋文琪(1962-),女,主任技师/硕士生导师,社会兼职:中国医师协会检验医师分会儿科疾病检验医学专业委员会主任委员,中华医学会儿科学分会临床检验学组副组长,国家卫计委妇幼健康研究会检验医学专业委员会副主任委员。专业特长:主持和参与“十二五”重大课题、国家自然科学基金面上项目、省部级、北京市卫计委等课题7项,建立中国儿童临床常规检验指标参考区间及相关行业标准。
更新日期/Last Update: 2018-04-16